2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one

early growth response 1 ; Homo sapiens







35 Article(s)
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1 26922429 Epigallocatechin-3-gallate inhibits transforming-growth-factor-β1-induced collagen synthesis by suppressing early growth response-1 in human buccal mucosal fibroblasts. 2017 Feb 1
2 26084532 Early Growth Response Protein-1 Expression by Insulin-Like Growth Factor-1 Requires ROS-Dependent Activation of ERK1/2 and PKB Pathways in Vascular Smooth Muscle Cells. 2016 Jan 1
3 24436257 Arecoline stimulated early growth response-1 production in human buccal fibroblasts: suppression by epigallocatechin-3-gallate. 2015 Apr 1
4 25591955 Angiotensin II-induced Egr-1 expression is suppressed by peroxisome proliferator-activated receptor-γ ligand 15d-PGJ₂ in macrophages. 2015 1
5 25981695 Iron deficiency upregulates Egr1 expression. 2015 Jul 1
6 21212994 TNF-α induces early growth response gene-1 expression via ERK1/2 activation in endothelial cells. 2013 Feb 1
7 20959155 Formononetin accelerates wound repair by the regulation of early growth response factor-1 transcription factor through the phosphorylation of the ERK and p38 MAPK pathways. 2011 Jan 1
8 22593802 Transcriptional Regulation of EGR1 by EGF and the ERK Signaling Pathway in Prostate Cancer Cells. 2011 Sep 3
9 20018936 Phosphorylation and acetylation of histone H3 and autoregulation by early growth response 1 mediate interleukin 1beta induction of early growth response 1 transcription. 2010 Mar 1
10 19526316 Hepatocyte growth factor induced up-regulations of VEGF through Egr-1 in hepatocellular carcinoma cells. 2009 1
11 19557503 Egr-1 upregulates OPN through direct binding to its promoter and OPN upregulates Egr-1 via the ERK pathway. 2009 Dec 1
12 19562672 A new mechanism of gastric epithelial injury induced by acid exposure: the role of Egr-1 and ERK signaling pathways. 2009 Sep 1 1
13 17911534 FP prostanoid receptor-mediated induction of the expression of early growth response factor-1 by activation of a Ras/Raf/mitogen-activated protein kinase signaling cascade. 2008 Jan 2
14 17230532 Neurotensin stimulates expression of early growth response gene-1 and EGF receptor through MAP kinase activation in human colonic epithelial cells. 2007 Apr 15 1
15 17474086 P2X(7) receptor stimulation upregulates Egr-1 biosynthesis involving a cytosolic Ca(2+) rise, transactivation of the EGF receptor and phosphorylation of ERK and Elk-1. 2007 Oct 1
16 17715378 Activation of nonsteroidal anti-inflammatory drug-activated gene-1 via extracellular signal-regulated kinase 1/2 mitogen-activated protein kinase revealed a isochaihulactone-triggered apoptotic pathway in human lung cancer A549 cells. 2007 Nov 2
17 16079301 Transcriptional regulation of activating transcription factor 3 involves the early growth response-1 gene. 2005 Nov 2
18 15075204 Calcium-regulated changes in mitochondrial phenotype in skeletal muscle cells. 2004 May 1
19 15292961 The zinc finger transcription factor Egr-1 is upregulated in arsenite-treated human keratinocytes. 2004 Aug 1
20 15449318 Egr-1 is activated by 17beta-estradiol in MCF-7 cells by mitogen-activated protein kinase-dependent phosphorylation of ELK-1. 2004 Nov 15 1
21 12457461 Early stimulation and late inhibition of peroxisome proliferator-activated receptor gamma (PPAR gamma) gene expression by transforming growth factor beta in human aortic smooth muscle cells: role of early growth-response factor-1 (Egr-1), activator protein 1 (AP1) and Smads. 2003 Mar 15 1
22 11948693 Epidermal growth factor and thrombin induced proliferation of immortalized human keratinocytes is coupled to the synthesis of Egr-1, a zinc finger transcriptional regulator. 2002 1
23 12384223 Substance P induced biosynthesis of the zinc finger transcription factor Egr-1 in human glioma cells requires activation of the epidermal growth factor receptor and of extracellular signal-regulated protein kinase. 2002 Oct 31 1
24 12483323 Functional role of Egr-1 mediating VEGF-induced tissue factor expression in the retinal capillary endothelium. 2002 Dec 1
25 11121417 Induction of early growth response-1 gene expression by calmodulin antagonist trifluoperazine through the activation of Elk-1 in human fibrosarcoma HT1080 cells. 2001 Mar 16 2
26 11520792 Lipopolysaccharide activation of the MEK-ERK1/2 pathway in human monocytic cells mediates tissue factor and tumor necrosis factor alpha expression by inducing Elk-1 phosphorylation and Egr-1 expression. 2001 Sep 1 1
27 11550093 Induction of Egr-1 expression by the retinoid AHPN in human lung carcinoma cells is dependent on activated ERK1/2. 2001 Apr 1
28 10753834 Granulocyte-macrophage colony-stimulating factor stimulation results in phosphorylation of cAMP response element-binding protein through activation of pp90RSK. 2000 Apr 15 1
29 9950805 Epithelial injury induces egr-1 and fos expression by a pathway involving protein kinase C and ERK. 1999 Feb 1
30 10079272 Early growth response factor-1 induction by injury is triggered by release and paracrine activation by fibroblast growth factor-2. 1999 Mar 1
31 10205148 Modulation of Ras/Raf/extracellular signal-regulated kinase pathway by reactive oxygen species is involved in cyclic strain-induced early growth response-1 gene expression in endothelial cells. 1999 Apr 16 1
32 10446131 Angiotensin II (ATII)-inducible platelet-derived growth factor A-chain gene expression is p42/44 extracellular signal-regulated kinase-1/2 and Egr-1-dependent and mediated via the ATII type 1 but not type 2 receptor. Induction by ATII antagonized by nitric oxide. 1999 Aug 20 1
33 10501181 Cholinergic stimulation of early growth response-1 DNA binding activity requires protein kinase C and mitogen-activated protein kinase kinase activation and is inhibited by sodium valproate in SH-SY5Y cells. 1999 Oct 1
34 9616225 Fluid shear stress activation of egr-1 transcription in cultured human endothelial and epithelial cells is mediated via the extracellular signal-related kinase 1/2 mitogen-activated protein kinase pathway. 1998 Jun 1 1
35 9755064 Hypotonicity activates transcription through ERK-dependent and -independent pathways in renal cells. 1998 Oct 1