| 1 |
31087493 | Cyclooxygenase-2 is acutely induced by CCAAT/enhancer-binding protein β to produce prostaglandin E 2 and F 2α following gonadotropin stimulation in Leydig cells. | 2019 Jul |
1 |
| 2 |
29636862 | Cyclooxygenase-2 deficiency causes delayed ossification of lumbar vertebral endplates. | 2018 |
1 |
| 3 |
23042097 | Hypoxia-inducible factor-2α is essential in activating the COX2/mPGES-1/PGE2 signaling axis in colon cancer. | 2013 Jan |
1 |
| 4 |
23046379 | Immune-induced expression of lipocalin-2 in brain endothelial cells: relationship with interleukin-6, cyclooxygenase-2 and the febrile response. | 2013 Mar |
1 |
| 5 |
23053397 | The role of PGE2-associated inflammatory responses in gastric cancer development. | 2013 Mar |
3 |
| 6 |
23420676 | Endogenous PGE(2) induces MCP-1 expression via EP4/p38 MAPK signaling in melanoma. | 2013 Feb |
2 |
| 7 |
23639875 | Prostaglandin E2 acts via bone marrow macrophages to block PTH-stimulated osteoblast differentiation in vitro. | 2013 Sep |
1 |
| 8 |
23943621 | Coordinate functional regulation between microsomal prostaglandin E synthase-1 (mPGES-1) and peroxisome proliferator-activated receptor γ (PPARγ) in the conversion of white-to-brown adipocytes. | 2013 Sep 27 |
1 |
| 9 |
21881002 | Lithium reduces aquaporin-2 transcription independent of prostaglandins. | 2012 Jan 1 |
1 |
| 10 |
22082586 | β-catenin represses expression of the tumour suppressor 15-prostaglandin dehydrogenase in the normal intestinal epithelium and colorectal tumour cells. | 2012 Sep |
2 |
| 11 |
22522619 | PTGS-2-PTGER2/4 signaling pathway partially protects from diabetogenic toxicity of streptozotocin in mice. | 2012 Jul |
1 |
| 12 |
22548186 | Capsaicin, a TRPV1 Ligand, Suppresses Bone Resorption by Inhibiting the Prostaglandin E Production of Osteoblasts, and Attenuates the Inflammatory Bone Loss Induced by Lipopolysaccharide. | 2012 |
1 |
| 13 |
22571318 | Multi-walled carbon nanotubes induce COX-2 and iNOS expression via MAP kinase-dependent and -independent mechanisms in mouse RAW264.7 macrophages. | 2012 May 9 |
1 |
| 14 |
22573380 | Temporal expression of the PGE2 synthetic system in the kidney is associated with the time frame of renal developmental vulnerability to cyclooxygenase-2 inhibition. | 2012 Jul 15 |
1 |
| 15 |
22628037 | Activation of the MyD88 signaling pathway inhibits ischemia-reperfusion injury in the small intestine. | 2012 Aug 1 |
1 |
| 16 |
22648443 | Effect of mifepristone on COX-2 both in eutopic and ectopic endometrium in mouse endometriotic model. | 2012 Oct |
1 |
| 17 |
22728095 | Saikosaponin a and its epimer saikosaponin d exhibit anti-inflammatory activity by suppressing activation of NF-κB signaling pathway. | 2012 Sep |
1 |
| 18 |
22970288 | Synergistic suppression of early phase of adipogenesis by microsomal PGE synthase-1 (PTGES1)-produced PGE2 and aldo-keto reductase 1B3-produced PGF2α. | 2012 |
1 |
| 19 |
21075851 | Anti-inflammatory role of microsomal prostaglandin E synthase-1 in a model of neuroinflammation. | 2011 Jan 21 |
1 |
| 20 |
21272610 | Anti-inflammatory activity of Angelica dahurica ethanolic extract on RAW264.7 cells via upregulation of heme oxygenase-1. | 2011 May |
1 |
| 21 |
21419570 | The soluble EP2 receptor FuEP2/Ex2 suppresses endometrial cancer cell growth in an orthotopic xenograft model in nude mice. | 2011 Jul 1 |
1 |
| 22 |
21716255 | Cyclooxygenase-2-dependent phosphorylation of the pro-apoptotic protein Bad inhibits tonicity-induced apoptosis in renal medullary cells. | 2011 Nov |
1 |
| 23 |
21873451 | Airway remodeling in murine asthma correlates with a defect in PGE2 synthesis by lung fibroblasts. | 2011 Nov |
1 |
| 24 |
22012553 | The role of the EP receptors for prostaglandin E2 in skin and skin cancer. | 2011 Dec |
2 |
| 25 |
20001844 | Compressive force induces osteoclast differentiation via prostaglandin E(2) production in MC3T3-E1 cells. | 2010 Apr |
1 |
| 26 |
20034551 | Anti-inflammatory and anti-arthritic activity of total flavonoids of the roots of Sophora flavescens. | 2010 Feb 17 |
2 |
| 27 |
20167866 | Cooperation of TLR2 with MyD88, PI3K, and Rac1 in lipoteichoic acid-induced cPLA2/COX-2-dependent airway inflammatory responses. | 2010 Apr |
2 |
| 28 |
20435922 | Resolution of inflammation in murine autoimmune arthritis is disrupted by cyclooxygenase-2 inhibition and restored by prostaglandin E2-mediated lipoxin A4 production. | 2010 Jun 1 |
2 |
| 29 |
20530000 | Targeted deletions of cyclooxygenase-2 and atherogenesis in mice. | 2010 Jun 22 |
1 |
| 30 |
20970329 | Sulfonamide derivatives of styrylheterocycles as a potent inhibitor of COX-2-mediated prostaglandin E2 production. | 2010 Dec 1 |
1 |
| 31 |
19097981 | Persistent inactivation of macrophage cyclooxygenase-2 in mycobacterial pulmonary inflammation. | 2009 Aug |
2 |
| 32 |
19318548 | Induction of prostaglandin E2 pathway promotes gastric hamartoma development with suppression of bone morphogenetic protein signaling. | 2009 Apr 1 |
1 |
| 33 |
19357295 | Renal and cardiovascular characterization of COX-2 knockdown mice. | 2009 Jun |
1 |
| 34 |
19643929 | Distinct roles for basal and induced COX-2 in podocyte injury. | 2009 Sep |
2 |
| 35 |
19739103 | Thrombin induces cyclooxygenase-2 expression and prostaglandin E2 release via PAR1 activation and ERK1/2- and p38 MAPK-dependent pathway in murine macrophages. | 2009 Dec 1 |
1 |
| 36 |
19776176 | Delphinidin suppresses ultraviolet B-induced cyclooxygenases-2 expression through inhibition of MAPKK4 and PI-3 kinase. | 2009 Nov |
2 |
| 37 |
19923455 | Matrix metalloproteinase (MMP)-1 and MMP-3 induce macrophage MMP-9: evidence for the role of TNF-alpha and cyclooxygenase-2. | 2009 Dec 15 |
1 |
| 38 |
19929415 | COX-2 inhibitors are contraindicated for treatment of combined injury. | 2009 Dec |
4 |
| 39 |
18055759 | Antitumorigenic effects of peroxisome proliferator-activated receptor-gamma in non-small-cell lung cancer cells are mediated by suppression of cyclooxygenase-2 via inhibition of nuclear factor-kappaB. | 2008 Mar |
1 |
| 40 |
18096720 | High-glucose-induced prostaglandin E(2) and peroxisome proliferator-activated receptor delta promote mouse embryonic stem cell proliferation. | 2008 Mar |
2 |
| 41 |
18157587 | The role of heme oxygenase-1 in down regulation of PGE2 production by taurine chloramine and taurine bromamine in J774.2 macrophages. | 2008 Aug |
2 |
| 42 |
18329054 | The cyclooxygenase-2/prostaglandin E2 pathway is involved in the somatostatin-induced decrease of epileptiform bursting in the mouse hippocampus. | 2008 Apr |
1 |
| 43 |
18355636 | Altered GABAergic neurotransmission is associated with increased kainate-induced seizure in prostaglandin-endoperoxide synthase-2 deficient mice. | 2008 Mar 28 |
1 |
| 44 |
18391113 | Absence of cyclooxygenase-2 exacerbates hypoxia-induced pulmonary hypertension and enhances contractility of vascular smooth muscle cells. | 2008 Apr 22 |
2 |
| 45 |
18419601 | Consequences of altered eicosanoid patterns for nociceptive processing in mPGES-1-deficient mice. | 2008 Apr |
2 |
| 46 |
18596135 | Age-associated changes in immune and inflammatory responses: impact of vitamin E intervention. | 2008 Oct |
2 |
| 47 |
18762248 | PGE(2) induces COX-2 expression in podocytes via the EP(4) receptor through a PKA-independent mechanism. | 2008 Nov |
3 |
| 48 |
16820798 | Cyclooxygenase-2 does not contribute to postischemic production of reactive oxygen species. | 2007 Mar |
3 |
| 49 |
17049841 | Liver X receptor ligands inhibit the lipopolysaccharide-induced expression of microsomal prostaglandin E synthase-1 and diminish prostaglandin E2 production in murine peritoneal macrophages. | 2007 Jan |
2 |
| 50 |
17109078 | Inhibitory effects of neoandrographolide on nitric oxide and prostaglandin E2 production in LPS-stimulated murine macrophage. | 2007 Apr |
2 |