Cysteine

rhodopsin ; Homo sapiens







45 Article(s)
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1 28536260 Functional role of the three conserved cysteines in the N domain of visual arrestin-1. 2017 Jul 28 2
2 24692562 Intramolecular interactions that induce helical rearrangement upon rhodopsin activation: light-induced structural changes in metarhodopsin IIa probed by cysteine S-H stretching vibrations. 2014 May 16 2
3 24724832 Rhodopsin TM6 can interact with two separate and distinct sites on arrestin: evidence for structural plasticity and multiple docking modes in arrestin-rhodopsin binding. 2014 May 27 1
4 27493492 Mapping of the local environmental changes in proteins by cysteine scanning. 2014 1
5 24106275 Retinitis pigmentosa mutants provide insight into the role of the N-terminal cap in rhodopsin folding, structure, and function. 2013 Nov 22 1
6 22352709 Rhodopsin forms a dimer with cytoplasmic helix 8 contacts in native membranes. 2012 Mar 6 1
7 22842041 Spatial arrangement of rhodopsin in retinal rod outer segment membranes studied by spin-labeling and pulsed electron double resonance. 2012 Aug 24 1
8 19934058 Cone photoreceptor mosaic disruption associated with Cys203Arg mutation in the M-cone opsin. 2009 Dec 8 1
9 18067244 Porphyrinmaleimides: towards thiol probes for cysteine residues in proteins. 2008 Jan 2
10 17009319 Predisposition of the dark state of rhodopsin to functional changes in structure. 2006 Dec 1 1
11 17014882 Metarhodopsin-II stabilization by crosslinked Gtalpha C-terminal peptides and implications for the mechanism of GPCR-G protein coupling. 2006 Dec 3
12 15840841 Cysteine 2.59(89) in the second transmembrane domain of human CB2 receptor is accessible within the ligand binding crevice: evidence for possible CB2 deviation from a rhodopsin template. 2005 Jul 1
13 14744159 NMR spectroscopy of phosphorylated wild-type rhodopsin: mobility of the phosphorylated C-terminus of rhodopsin in the dark and upon light activation. 2004 Feb 3 1
14 12590586 An opsin mutant with increased thermal stability. 2003 Feb 25 1
15 11866527 X-ray diffraction of heavy-atom labelled two-dimensional crystals of rhodopsin identifies the position of cysteine 140 in helix 3 and cysteine 316 in helix 8. 2002 Feb 22 2
16 12065750 Design, synthesis and pharmacological evaluation of 5-hydroxytryptamine(1a) receptor ligands to explore the three-dimensional structure of the receptor. 2002 Jul 1
17 12081478 Evidence that helix 8 of rhodopsin acts as a membrane-dependent conformational switch. 2002 Jul 2 1
18 12359230 Retinitis pigmentosa-associated rhodopsin mutations in three membrane-located cysteine residues present three different biochemical phenotypes. 2002 Oct 4 1
19 11320236 Structure and function in rhodopsin: Mass spectrometric identification of the abnormal intradiscal disulfide bond in misfolded retinitis pigmentosa mutants. 2001 Apr 24 2
20 11320237 Mapping of contact sites in complex formation between transducin and light-activated rhodopsin by covalent crosslinking: use of a photoactivatable reagent. 2001 Apr 24 1
21 11408595 Structural mimicry in G protein-coupled receptors: implications of the high-resolution structure of rhodopsin for structure-function analysis of rhodopsin-like receptors. 2001 Jul 1
22 11601970 Probing the dark state tertiary structure in the cytoplasmic domain of rhodopsin: proximities between amino acids deduced from spontaneous disulfide bond formation between Cys316 and engineered cysteines in cytoplasmic loop 1. 2001 Oct 23 1
23 11601971 Probing the dark state tertiary structure in the cytoplasmic domain of rhodopsin: proximities between amino acids deduced from spontaneous disulfide bond formation between cysteine pairs engineered in cytoplasmic loops 1, 3, and 4. 2001 Oct 23 1
24 11697851 Chemical modification of transducin with iodoacetic acid: transducin-alpha carboxymethylated at Cys(347) allows transducin binding to Light-activated rhodopsin but prevents its release in the presence of GTP. 2001 Nov 15 1
25 11106502 Light-induced conformational changes of rhodopsin probed by fluorescent alexa594 immobilized on the cytoplasmic surface. 2000 Dec 12 2
26 9880548 Conformational changes in rhodopsin. Movement of helix f detected by site-specific chemical labeling and fluorescence spectroscopy. 1999 Jan 15 1
27 10051572 Structure and function in rhodopsin: further elucidation of the role of the intradiscal cysteines, Cys-110, -185, and -187, in rhodopsin folding and function. 1999 Mar 2 6
28 10387035 Structural features and light-dependent changes in the sequence 306-322 extending from helix VII to the palmitoylation sites in rhodopsin: a site-directed spin-labeling study. 1999 Jun 22 1
29 10387036 Single-cysteine substitution mutants at amino acid positions 55-75, the sequence connecting the cytoplasmic ends of helices I and II in rhodopsin: reactivity of the sulfhydryl groups and their derivatives identifies a tertiary structure that changes upon light-activation. 1999 Jun 22 2
30 10508406 State-dependent disulfide cross-linking in rhodopsin. 1999 Sep 14 1
31 10508407 Tertiary interactions between transmembrane segments 3 and 5 near the cytoplasmic side of rhodopsin. 1999 Sep 14 1
32 10570143 NMR spectroscopy in studies of light-induced structural changes in mammalian rhodopsin: applicability of solution (19)F NMR. 1999 Nov 23 2
33 9477956 Disulfide bond exchange in rhodopsin. 1998 Feb 3 1
34 9797678 Ocular signs associated with a rhodopsin mutation (Cys-167-->Arg) in a family with autosomal dominant retinitis pigmentosa. 1998 Jun 1
35 9405601 Structure and function in rhodopsin: topology of the C-terminal polypeptide chain in relation to the cytoplasmic loops. 1997 Dec 23 1
36 8823930 Spin-labeling analysis of structure and dynamics in octopus rhodopsin. 1996 Aug 1
37 8864113 Requirement of rigid-body motion of transmembrane helices for light activation of rhodopsin. 1996 Nov 1 1
38 7612621 Mapping of the amino acids in the cytoplasmic loop connecting helices C and D in rhodopsin. Chemical reactivity in the dark state following single cysteine replacements. 1995 Jul 11 2
39 7972030 The palmitoylated cysteine of the cytoplasmic tail of alpha 2A-adrenergic receptors confers subtype-specific agonist-promoted downregulation. 1994 Nov 8 1
40 8052635 Structure and function in rhodopsin: covalent crosslinking of the rhodopsin (metarhodopsin II)-transducin complex--the rhodopsin cytoplasmic face links to the transducin alpha subunit. 1994 Aug 2 4
41 8075342 Photoactivation of rhodopsin involves alterations in cysteine side chains: detection of an S-H band in the Meta I-->Meta II FTIR difference spectrum. 1994 Jun 5
42 8171030 Structure and function in rhodopsin: replacement by alanine of cysteine residues 110 and 187, components of a conserved disulfide bond in rhodopsin, affects the light-activated metarhodopsin II state. 1994 Apr 26 5
43 8218279 Formation of the meta II photointermediate is accompanied by conformational changes in the cytoplasmic surface of rhodopsin. 1993 Nov 16 1
44 8469290 Projection structure of rhodopsin. 1993 Apr 22 1
45 3192520 Mapping of the carboxyl terminus within the tertiary structure of transducin's alpha subunit using the heterobifunctional cross-linking reagent, 125I-N-(3-iodo-4-azidophenylpropionamido-S-(2-thiopyridyl) cysteine. 1988 Dec 5 3