Cholesterol

low density lipoprotein receptor ; Mus musculus







461 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 33576385 Deficiency of inactive rhomboid protein 2 (iRhom2) attenuates diet-induced hyperlipidaemia and early atherogenesis. 2022 Jan 7 1
2 34036816 Pcsk9 Knockout Aggravated Experimental Apical Periodontitis via LDLR. 2022 Jan 2
3 34816633 Pcsk9 Deletion Promotes Murine Nonalcoholic Steatohepatitis and Hepatic Carcinogenesis: Role of Cholesterol. 2022 Apr 1
4 34975320 GPR43 activation-mediated lipotoxicity contributes to podocyte injury in diabetic nephropathy by modulating the ERK/EGR1 pathway. 2022 2
5 35065166 Hepatocellular BChE as a therapeutic target to ameliorate hypercholesterolemia through PRMT5 selective degradation to restore LDL receptor transcription. 2022 Mar 15 2
6 35101425 Comparison between genetic and pharmaceutical disruption of Ldlr expression for the development of atherosclerosis. 2022 Mar 1
7 35120132 Oxidant resistant human apolipoprotein A-I functions similarly to the unmodified human isoform in delaying atherosclerosis progression and promoting atherosclerosis regression in hyperlipidemic mice. 2022 1
8 35130916 Lowering blood cholesterol does not affect neuroinflammation in experimental autoimmune encephalomyelitis. 2022 Feb 7 3
9 35189703 Ablation of Plasma Prekallikrein Decreases Low-Density Lipoprotein Cholesterol by Stabilizing Low-Density Lipoprotein Receptor and Protects Against Atherosclerosis. 2022 Mar 2
10 35369785 Niacin promotes the efflux of lysosomal cholesterol from macrophages via the CD38/NAADP signaling pathway. 2022 Apr 2 1
11 35428331 L-Arabinose improves hypercholesterolemia via regulating bile acid metabolism in high-fat-high-sucrose diet-fed mice. 2022 Apr 15 2
12 35552680 The Multifaceted Biology of PCSK9. 2022 May 12 2
13 35567428 Alteration in Rab11-mediated endocytic trafficking of LDL receptor contributes to angiotensin II-induced cholesterol accumulation and injury in podocytes. 2022 Jun 2
14 35571088 Di'ao Xinxuekang Capsule Improves the Anti-Atherosclerotic Effect of Atorvastatin by Downregulating the SREBP2/PCSK9 Signalling Pathway. 2022 2
15 32931583 Adoptive transfer of CX3CR1 transduced-T regulatory cells improves homing to the atherosclerotic plaques and dampens atherosclerosis progression. 2021 Jul 27 1
16 33190783 Inhibition of microRNA-128-3p attenuates hypercholesterolemia in mouse model. 2021 Jan 1 1
17 33369150 Combination of hyperglycaemia and hyperlipidaemia induces endothelial dysfunction: Role of the endothelin and nitric oxide systems. 2021 Feb 1
18 33456582 Exosome-based Ldlr gene therapy for familial hypercholesterolemia in a mouse model. 2021 2
19 33500241 Mutation in the distal NPxY motif of LRP1 alleviates dietary cholesterol-induced dyslipidemia and tissue inflammation. 2021 1
20 33658436 Increased Hepatic Lipogenesis Elevates Liver Cholesterol Content. 2021 Feb 28 1
21 33667684 Beneficial effects of brown fat activation on top of PCSK9 inhibition with alirocumab on dyslipidemia and atherosclerosis development in APOE*3-Leiden.CETP mice. 2021 May 1
22 33761762 Sexually Dimorphic Relationships Among Saa3 (Serum Amyloid A3), Inflammation, and Cholesterol Metabolism Modulate Atherosclerosis in Mice. 2021 Jun 1
23 33815271 Cholesterol Accumulation as a Driver of Hepatic Inflammation Under Translational Dietary Conditions Can Be Attenuated by a Multicomponent Medicine. 2021 1
24 33977967 Sterol sulfate alleviates atherosclerosis via mediating hepatic cholesterol metabolism in ApoE-/- mice. 2021 Jun 8 1
25 33992809 Substantial PCSK9 inactivation in β-cells does not modify glucose homeostasis or insulin secretion in mice. 2021 Aug 2
26 34107900 ERK activation via A1542/3 limonoids attenuates erythroleukemia through transcriptional stimulation of cholesterol biosynthesis genes. 2021 Jun 9 1
27 34251816 LXR-Mediated Regulation of Marine-Derived Piericidins Aggravates High-Cholesterol Diet-Induced Cholesterol Metabolism Disorder in Mice. 2021 Jul 22 2
28 34311268 LDLR expression in the cochlea suggests a role in endolymph homeostasis and cochlear amplification. 2021 Sep 15 3
29 34422975 Hepatic paraoxonase 1 ameliorates dysfunctional high-density lipoprotein and atherosclerosis in scavenger receptor class B type I deficient mice. 2021 Jul 2
30 34461308 Hormone-sensitive lipase deficiency affects the expression of SR-BI, LDLr, and ABCA1 receptors/transporters involved in cellular cholesterol uptake and efflux and disturbs fertility in mouse testis. 2021 Dec 1
31 34606887 The PCSK9 discovery, an inactive protease with varied functions in hypercholesterolemia, viral infections, and cancer. 2021 1
32 34615375 Turnover Rates of the Low-Density Lipoprotein Receptor and PCSK9: Added Dimension to the Cholesterol Homeostasis Model. 2021 Dec 7
33 34638955 Mouse Liver Compensates Loss of Sgpl1 by Secretion of Sphingolipids into Blood and Bile. 2021 Sep 30 1
34 34680102 Rosmarinic Acid Exhibits a Lipid-Lowering Effect by Modulating the Expression of Reverse Cholesterol Transporters and Lipid Metabolism in High-Fat Diet-Fed Mice. 2021 Oct 6 1
35 34796210 Dietary-Induced Elevations of Triglyceride-Rich Lipoproteins Promote Atherosclerosis in the Low-Density Lipoprotein Receptor Knockout Syrian Golden Hamster. 2021 2
36 34901211 Wnt2 Contributes to the Development of Atherosclerosis. 2021 1
37 34927009 PCSK9 Axis-Targeting Pseurotin A as a Novel Prostate Cancer Recurrence Suppressor Lead. 2021 Dec 10 2
38 31815695 LDL Receptor Deficiency Does not Alter Brain Amyloid-β Levels but Causes an Exacerbation of Apoptosis. 2020 2
39 31870234 Vaccine Against PCSK9 Improved Renal Fibrosis by Regulating Fatty Acid β-Oxidation. 2020 Jan 7 1
40 31975555 Methionine sulfoxide reductase A attenuates atherosclerosis via repairing dysfunctional HDL in scavenger receptor class B type I deficient mice. 2020 Mar 1
41 31996466 A dual apolipoprotein C-II mimetic-apolipoprotein C-III antagonist peptide lowers plasma triglycerides. 2020 Jan 29 1
42 32027669 Cyp1b1 directs Srebp-mediated cholesterol and retinoid synthesis in perinatal liver; Association with retinoic acid activity during fetal development. 2020 1
43 32244519 Evaluation of the Potential Role of Proprotein Convertase Subtilisin/Kexin Type 9 (PCSK9) in Niemann-Pick Disease, Type C1. 2020 Mar 31 1
44 32295848 LDL uptake-dependent phosphatidylethanolamine translocation to the cell surface promotes fusion of osteoclast-like cells. 2020 May 27 1
45 32412785 Lactobacillus reuteri attenuates cardiac injury without lowering cholesterol in low-density lipoprotein receptor-deficient mice fed standard chow. 2020 Jul 1 2
46 32423823 Loss of core fucosylation reduces low-density lipoprotein receptor expression in hepatocytes by inducing PCSK9 production. 2020 Jun 30 1
47 32466086 Impact of the Gut Microbiota on Atorvastatin Mediated Effects on Blood Lipids. 2020 May 25 1
48 32475913 8-HEPE-Concentrated Materials from Pacific Krill Improve Plasma Cholesterol Levels and Hepatic Steatosis in High Cholesterol Diet-Fed Low-Density Lipoprotein (LDL) Receptor-Deficient Mice. 2020 1
49 32495699 LDL Receptor Regulates the Reverse Transport of Macrophage-Derived Unesterified Cholesterol via Concerted Action of the HDL-LDL Axis: Insight From Mouse Models. 2020 Aug 28 1
50 32522007 SR-BI (Scavenger Receptor BI), Not LDL (Low-Density Lipoprotein) Receptor, Mediates Adrenal Stress Response-Brief Report. 2020 Aug 2