Guanosine Triphosphate

GNAS complex locus ; Homo sapiens







47 Article(s)
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Pub. Year
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1 34587755 Constitutively Activating GNAS Somatic Mutation in Right Ventricular Outflow Tract Tachycardia. 2021 Oct 2
2 32700107 The biological basis and function of GNAS mutation in pseudomyxoma peritonei: a review. 2020 Sep 9
3 29491039 The N54-αs Mutant Has Decreased Affinity for βγ and Suggests a Mechanism for Coupling Heterotrimeric G Protein Nucleotide Exchange with Subunit Dissociation. 2018 May 1
4 23288949 Intragenic suppression of a constitutively active allele of Gsα associated with McCune-Albright syndrome. 2013 Apr 1
5 19550078 Prevalence of TSH receptor and Gsalpha mutations in 45 autonomously functioning thyroid nodules in Japan. 2009 1
6 18258741 The same mutation in Gsalpha and transducin alpha reveals behavioral differences between these highly homologous G protein alpha-subunits. 2008 Feb 19 2
7 18373982 Structural model of a complex between the heterotrimeric G protein, Gsalpha, and tubulin. 2008 Jun 1
8 19189654 Lack of involvement of the GNAS1 T393C polymorphism in prostate cancer risk in a Japanese population. 2008 Nov-Dec 2
9 17727271 What is the role of the helical domain of Gsalpha in the GTPase reaction? 2007 Sep 25 2
10 15368366 Mutation of the highly conserved Arg165 and Glu168 residues of human Gsalpha disrupts the alphaD-alphaE loop and enhances basal GDP/GTP exchange rate. 2004 Oct 1 1
11 11318657 Inhibition of GDP/GTP exchange on G alpha subunits by proteins containing G-protein regulatory motifs. 2001 May 1 1
12 10649434 Mutagenesis in the switch IV of the helical domain of the human Gsalpha reduces its GDP/GTP exchange rate. 2000 Jan 2
13 10714366 Gs alpha mutations in hyperfunctioning thyroid adenomas. 1999 Nov-Dec 1
14 9419378 Gsalpha-selective G protein antagonists. 1998 Jan 6 1
15 9729456 Restricting mobility of Gsalpha relative to the beta2-adrenoceptor enhances adenylate cyclase activity by reducing Gsalpha GTPase activity. 1998 Sep 15 1
16 9744820 GTP analogue hydrolysis by the Gs protein: implication for the role of catalytic glutamine in the GTPase reaction. 1998 Aug 21 1
17 9876352 GNAS1 mutational analysis in pseudohypoparathyroidism. 1998 Oct 1
18 9296350 Evidence for the shuttle model for Gs alpha activation of adenylyl cyclase. 1997 Jul 1 1
19 9328353 A novel mutation adjacent to the switch III domain of G(S alpha) in a patient with pseudohypoparathyroidism. 1997 Oct 1
20 9362361 Alterations in guanine nucleotide regulatory protein expression and activity in human hepatocellular carcinoma. 1997 Nov 1
21 9363787 Rescue of a mutant G-protein by substrate-assisted catalysis. 1997 Oct 1 4
22 9395396 Crystal structure of the adenylyl cyclase activator Gsalpha. 1997 Dec 12 1
23 9447300 Mutations in exon 7 of the GTP-binding protein Gs alpha were not a common cause of pseudohypoparathyroidism with Albright's hereditary osteodystrophy in Japanese. 1997 Aug 1
24 8621516 Chloride effects on Gs subunit dissociation. Fluoroaluminate binding to Gs does not cause subunit dissociation in the absence of chloride ion. 1996 Apr 12 1
25 8694741 [Changes in platelet adenylyl cyclase system in alcoholics]. 1996 Apr 1
26 8698339 Sporadic cardiac myxomas and tumors from patients with Carney complex are not associated with activating mutations of the Gs alpha gene. 1996 Aug 2
27 8736705 GTP binding to Gs does not promote subunit dissociation. 1996 Mar 3
28 8762039 G protein expression in human fetoplacental vascularization. Functional evidence for Gs alpha and Gi alpha subunits. 1996 May 1
29 8777140 Altered Gs alpha N-terminus affects Gs activity and interaction with the G beta gamma subunit complex in cell membranes but not in solution. 1996 Jan 4
30 8865363 GTP synthases. Proton pumping and phosphorylation in ligand-receptor-G alpha-protein complexes. 1996 1
31 7545394 Identification of alpha-subunits of trimeric GTP-binding proteins in human platelets by RT-PCR. 1995 Sep 5 1
32 7768948 Tissue inhibitor of metalloproteinase-2 stimulates fibroblast proliferation via a cAMP-dependent mechanism. 1995 Jun 2 1
33 7961906 Requirement for intramolecular domain interaction in activation of G protein alpha subunit by aluminum fluoride and GDP but not by GTP gamma S. 1994 Nov 25 1
34 7989376 2',3'-Dialdehyde GTP as an irreversible G protein antagonist. Disruption and reconstitution of G protein-mediated signal transduction in cells and cell membranes. 1994 Dec 16 2
35 8063706 Mutation of valine residue unique to alpha subunit of Gs abolishes activation. 1994 Aug 19 1
36 8204622 Subtype-specific binding of azidoanilido-GTP by purified G protein alpha subunits. 1994 Jun 7 1
37 8974338 Alterations of receptor-G protein-adenylyl cyclase coupling in alcoholics. 1994 1
38 9063827 Reduced sensitivity to ethanol of Gs alpha and Gi/o alpha in the cerebral cortex of alcoholic patients. 1994 1
39 8102365 ADP-ribosylation of Gs by cholera toxin is potentiated by agonist activation of beta-adrenergic receptors in the absence of GTP. 1993 Aug 15 1
40 8380163 Mutagenesis of the amino-terminal glycine to alanine in Gs alpha subunit alters beta gamma-dependent properties and decreases adenylylcyclase activation. 1993 Jan 5 1
41 8396579 Activating mutations of the Gs alpha-gene in nonfunctioning pituitary tumors. 1993 Sep 2
42 8402195 Alterations of guanine nucleotide-binding proteins in post-mortem human brain in alcoholics. 1993 Aug 20 1
43 8485230 [Signal-conducting and low molecular weight GTP-binding proteins from the lung and endothelium: localization in membranes and cytosol, interaction with F-actin]. 1993 Mar 2
44 1861140 Splicing pattern of Gs alpha mRNA in human and rat brain. 1991 Sep 1
45 1906270 GTP-binding membrane proteins in activated and differentiating T cells. 1991 Jul 15 1
46 1938104 A synthetic peptide corresponding to a sequence in the GTPase activating protein inhibits p21ras stimulation and promotes guanine nucleotide exchange. 1991 Jul 2
47 3141007 Regional distribution of the expression of a human stimulatory GTP-binding protein alpha-subunit in the human brain studied by in situ hybridization. 1988 Aug 1