| 1 |
34772733 | EP300 Selectively Controls the Enhancer Landscape of MYCN-Amplified Neuroblastoma. | 2022 Mar 1 |
1 |
| 2 |
34974819 | Investigation of intermolecular interactions and binding mechanism of PU139 and PU141 molecules with p300 HAT enzyme via molecular docking, molecular dynamics simulations and binding free energy analysis. | 2022 Jan 3 |
1 |
| 3 |
35119862 | Dynamics of the Histone Acetyltransferase Lysine-Rich Loop in the Catalytic Core of the CREB-Binding Protein. | 2022 Feb 28 |
1 |
| 4 |
35500056 | Chiral Posttranslational Modification to Lysine ε-Amino Groups. | 2022 May 17 |
1 |
| 5 |
35512565 | Structure-activity relationship and antitumor activity of 1,4-pyrazine-containing inhibitors of histone acetyltransferases P300/CBP. | 2022 Jul 5 |
1 |
| 6 |
35551465 | Intrinsic epigenetic control of angiogenesis in induced pluripotent stem cell-derived endothelium regulates vascular regeneration. | 2022 May 12 |
1 |
| 7 |
35569250 | Discovery of novel benzimidazole derivatives as potent p300 bromodomain inhibitors with anti-proliferative activity in multiple cancer cells. | 2022 Jul 15 |
1 |
| 8 |
33187986 | A conserved acetylation switch enables pharmacological control of tubby-like protein stability. | 2021 Jan-Jun |
1 |
| 9 |
33313896 | Identification of lysine isobutyrylation as a new histone modification mark. | 2021 Jan 11 |
1 |
| 10 |
33400925 | Targeted degradation of the enhancer lysine acetyltransferases CBP and p300. | 2021 Apr 15 |
3 |
| 11 |
34019788 | Targeting histone acetylation dynamics and oncogenic transcription by catalytic P300/CBP inhibition. | 2021 May 20 |
1 |
| 12 |
34044126 | Cigarette smoke extract-induced downregulation of p300 is responsible for the impaired inflammatory cytokine response of macrophages. | 2021 Sep |
1 |
| 13 |
34071322 | Histone Deacetylase Inhibitors Ameliorate Morphological Defects and Hypoexcitability of iPSC-Neurons from Rubinstein-Taybi Patients. | 2021 May 28 |
2 |
| 14 |
34179622 | Co-occurrence of Protein Crotonylation and 2-Hydroxyisobutyrylation in the Proteome of End-Stage Renal Disease. | 2021 Jun 22 |
1 |
| 15 |
34201346 | CBP/p300: Critical Co-Activators for Nuclear Steroid Hormone Receptors and Emerging Therapeutic Targets in Prostate and Breast Cancers. | 2021 Jun 8 |
1 |
| 16 |
34251718 | Leukemogenesis via aberrant self-renewal by the MLL/AEP-mediated transcriptional activation system. | 2021 Oct |
1 |
| 17 |
34255515 | Controlling Intramolecular Interactions in the Design of Selective, High-Affinity Ligands for the CREBBP Bromodomain. | 2021 Jul 22 |
3 |
| 18 |
34331108 | Repurposing proscillaridin A in combination with decitabine against embryonal rhabdomyosarcoma RD cells. | 2021 Nov |
3 |
| 19 |
34369620 | Acetylation of Abelson interactor 1 at K416 regulates actin cytoskeleton and smooth muscle contraction. | 2021 Sep |
1 |
| 20 |
34385547 | Interplay between p300 and HDAC1 regulate acetylation and stability of Api5 to regulate cell proliferation. | 2021 Aug 12 |
1 |
| 21 |
34758305 | Interplay between protein acetylation and ubiquitination controls MCL1 protein stability. | 2021 Nov 9 |
1 |
| 22 |
34801827 | Design, synthesis and biological evaluation of a novel spiro oxazolidinedione as potent p300/CBP HAT inhibitor for the treatment of ovarian cancer. | 2021 Dec 15 |
1 |
| 23 |
32173363 | A novel histone acetyltransferase inhibitor A485 improves sensitivity of non-small-cell lung carcinoma cells to TRAIL. | 2020 May |
1 |
| 24 |
32181984 | Early Drug-Discovery Efforts towards the Identification of EP300/CBP Histone Acetyltransferase (HAT) Inhibitors. | 2020 Jun 4 |
1 |
| 25 |
32314924 | Discovery, Structure-Activity Relationship, and Biological Activity of Histone-Competitive Inhibitors of Histone Acetyltransferases P300/CBP. | 2020 May 14 |
1 |
| 26 |
32457045 | Regulation of poly(a)-specific ribonuclease activity by reversible lysine acetylation. | 2020 Jul 24 |
1 |
| 27 |
32460017 | Pyruvate Kinase M2 Promotes the Activation of Dendritic Cells by Enhancing IL-12p35 Expression. | 2020 May 26 |
1 |
| 28 |
32522824 | p300-Mediated Acetylation of Histone Demethylase JMJD1A Prevents Its Degradation by Ubiquitin Ligase STUB1 and Enhances Its Activity in Prostate Cancer. | 2020 Aug 1 |
1 |
| 29 |
32763975 | Acetylation modulates the Fanconi anemia pathway by protecting FAAP20 from ubiquitin-mediated proteasomal degradation. | 2020 Oct 2 |
1 |
| 30 |
32765954 | p300 in Cardiac Development and Accelerated Cardiac Aging. | 2020 Jul |
2 |
| 31 |
32979659 | Computational insights into the binding mode of curcumin analogues against EP300 HAT domain as potent acetyltransferase inhibitors. | 2020 Dec |
1 |
| 32 |
33457194 | p300-Catalyzed Lysine Crotonylation Promotes the Proliferation, Invasion, and Migration of HeLa Cells via Heterogeneous Nuclear Ribonucleoprotein A1. | 2020 |
6 |
| 33 |
30856481 | CBP/p300 in brain development and plasticity: disentangling the KAT's cradle. | 2019 Dec |
4 |
| 34 |
30877109 | Regulation of miRNA Biogenesis and Histone Modification by K63-Polyubiquitinated DDX17 Controls Cancer Stem-like Features. | 2019 May 15 |
1 |
| 35 |
30962627 | Bromodomain inhibition of the coactivators CBP/EP300 facilitate cellular reprogramming. | 2019 May |
1 |
| 36 |
31054974 | Acetylation of PHF5A Modulates Stress Responses and Colorectal Carcinogenesis through Alternative Splicing-Mediated Upregulation of KDM3A. | 2019 Jun 20 |
1 |
| 37 |
29584949 | A Chemical Probe for Protein Crotonylation. | 2018 Apr 11 |
1 |
| 38 |
29629903 | ZMYND8 acetylation mediates HIF-dependent breast cancer progression and metastasis. | 2018 May 1 |
1 |
| 39 |
29775581 | p300-Mediated Lysine 2-Hydroxyisobutyrylation Regulates Glycolysis. | 2018 May 17 |
4 |
| 40 |
29932303 | Quantitative Crotonylome Analysis Expands the Roles of p300 in the Regulation of Lysine Crotonylation Pathway. | 2018 Aug |
7 |
| 41 |
29944992 | Generation of the Rubinstein-Taybi syndrome type 2 patient-derived induced pluripotent stem cell line (IAIi001-A) carrying the EP300 exon 23 stop mutation c.3829A > T, p.(Lys1277*). | 2018 Jul |
1 |
| 42 |
30060157 | Oocyte-Derived Factors (GDF9 and BMP15) and FSH Regulate AMH Expression Via Modulation of H3K27AC in Granulosa Cells. | 2018 Sep 1 |
1 |
| 43 |
30089272 | Deficiency of PKD2L1 (TRPP3) Exacerbates Pathological Cardiac Hypertrophy by Augmenting NCX1-Mediated Mitochondrial Calcium Overload. | 2018 Aug 7 |
1 |
| 44 |
30135206 | The proto-oncogene Bcl3 induces immune checkpoint PD-L1 expression, mediating proliferation of ovarian cancer cells. | 2018 Oct 5 |
1 |
| 45 |
30140938 | MicroRNA 675 cooperates PKM2 to aggravate progression of human liver cancer stem cells induced from embryonic stem cells. | 2018 Oct |
1 |
| 46 |
30263097 | STAT3 is constitutively acetylated on lysine 685 residues in chronic lymphocytic leukemia cells. | 2018 Sep 14 |
1 |
| 47 |
30323286 | Transcription factor dimerization activates the p300 acetyltransferase. | 2018 Oct |
2 |
| 48 |
27820805 | Structure of p300 in complex with acyl-CoA variants. | 2017 Jan |
1 |
| 49 |
27989401 | CBP/p300 Bromodomains Regulate Amyloid-like Protein Aggregation upon Aberrant Lysine Acetylation. | 2017 Jan 19 |
1 |
| 50 |
28260048 | Octreotide inhibits the proliferation of gastric cancer cells through P300-HAT activity and the interaction of ZAC and P300. | 2017 Apr |
2 |