lazabemide

monoamine oxidase B ; Homo sapiens







30 Article(s)
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1 34641548 Selected Class of Enamides Bearing Nitro Functionality as Dual-Acting with Highly Selective Monoamine Oxidase-B and BACE1 Inhibitors. 2021 Oct 3 1
2 32443652 Novel Class of Chalcone Oxime Ethers as Potent Monoamine Oxidase-B and Acetylcholinesterase Inhibitors. 2020 May 18 1
3 31550216 Ethyl Acetohydroxamate Incorporated Chalcones: Unveiling a Novel Class of Chalcones for Multitarget Monoamine Oxidase-B Inhibitors Against Alzheimer's Disease. 2019 1
4 29195801 Discovery of potent and reversible MAO-B inhibitors as furanochalcones. 2018 Mar 1
5 29958546 Neuroimaging-pathological correlations of [18F]THK5351 PET in progressive supranuclear palsy. 2018 Jun 29 1
6 30143367 Design, synthesis and biological evaluation of lazabemide derivatives as inhibitors of monoamine oxidase. 2018 Sep 15 1
7 17570647 Specific binding of [3H]Ro 19-6327 (lazabemide) to monoamine oxidase B is increased in frontal cortex of suicide victims after controlling for age at death. 2008 Jan 2
8 12359039 Lazabemide, a selective, reversible monoamine oxidase B inhibitor, as an aid to smoking cessation. 2002 Oct 2
9 10688633 Imidazoline-binding domains on monoamine oxidase B and subpopulations of enzyme. 2000 Mar 1
10 10927030 Antioxidant activity of the monoamine oxidase B inhibitor lazabemide. 2000 Sep 1 3
11 10408736 Recent developments in the drug treatment of Alzheimer's disease. 1999 May 1
12 10626094 Safety study of lazabemide (Ro19-6327), a new MAO-B inhibitor, on cardiac arrhythmias and blood pressure of patients with Parkinson's disease. 1999 Nov-Dec 1
13 9466361 In vivo properties of N-(2-aminoethyl)-5-halogeno-2-pyridinecarboxamide 18F- and 123I-labelled reversible inhibitors of monoamine oxidase B. 1998 Jan 2
14 9056051 Pharmacokinetics and pharmacodynamics of single and multiple doses of the MAO-B inhibitor lazabemide in healthy subjects. 1997 Jan 4
15 9116589 Densities of I2-imidazoline receptors, alpha 2-adrenoceptors and monoamine oxidase B in brains of suicide victims. 1997 Jan 1
16 9394121 The density of monoamine oxidase B sites is not altered in the postmortem brain of alcoholics. 1997 Nov 2
17 8665924 Investigation on the structure of the active site of monoamine oxidase-B by affinity labeling with the selective inhibitor lazabemide and by site-directed mutagenesis. 1996 Mar 15 2
18 7601156 Structure/function relationships of mitochondrial monoamine oxidase A and B chimeric forms. 1995 Jun 15 1
19 7816197 Increased monoamine oxidase B activity in plaque-associated astrocytes of Alzheimer brains revealed by quantitative enzyme radioautography. 1994 Sep 2
20 7917773 Pharmacodynamics of lazabemide, a reversible and selective inhibitor of monoamine oxidase B. 1994 Jun 3
21 8155011 A controlled trial of lazabemide (Ro 19-6327) in levodopa-treated Parkinson's disease. Parkinson Study Group. 1994 Apr 3
22 8374913 Symptomatic anti-parkinsonian effects of monoamine oxidase-B inhibition: comparison of selegiline and lazabemide. 1993 Aug 2
23 8395564 Opposite age-dependent changes of alpha 2A-adrenoceptors and nonadrenoceptor [3H]idazoxan binding sites (I2-imidazoline sites) in the human brain: strong correlation of I2 with monoamine oxidase-B sites. 1993 Sep 1
24 8413955 Monoamine oxidase B (MAO B) inhibitor therapy in Parkinson's disease: the degree and reversibility of human brain MAO B inhibition by Ro 19 6327. 1993 Oct 5
25 8489205 A controlled trial of lazabemide (RO19-6327) in untreated Parkinson's disease. Parkinson Study Group. 1993 Apr 3
26 1904879 Measurement of cerebral monoamine oxidase B activity using L-[11C]deprenyl and dynamic positron emission tomography. 1991 Jul 1
27 1906004 Measurement of human cerebral monoamine oxidase type B (MAO-B) activity with positron emission tomography (PET): a dose ranging study with the reversible inhibitor Ro 19-6327. 1991 1
28 2122653 Ro 19-6327, a reversible and highly selective monoamine, oxidase B inhibitor: a novel tool to explore the MAO-B function in humans. 1990 1
29 2380287 Determination of the monoamine oxidase B inhibitor Ro 19-6327 in plasma by high-performance liquid chromatography using precolumn derivatization with fluorescamine and fluorescence detection. 1990 May 16 2
30 3126263 [3H]Ro 16-6491, a selective probe for affinity labelling of monoamine oxidase type B in human brain and platelet membranes. 1988 Apr 2