rasagiline

monoamine oxidase B ; Homo sapiens







179 Article(s)
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1 34977548 Rasagiline does not exacerbate autonomic blood pressure dysregulation in early or mild Parkinson's disease. 2022 1
2 35203982 Rasagiline Withdrawal Syndrome in Parkinson's Disease. 2022 Feb 5 2
3 35447344 The evaluation of N-propargylamine-2-aminotetralin as an inhibitor of monoamine oxidase. 2022 Jul 1 2
4 33818516 Evaluation of the combined activity of benzimidazole arylhydrazones as new anti-Parkinsonian agents: monoamine oxidase-B inhibition, neuroprotection and oxidative stress modulation. 2021 Nov 1
5 33887441 Novel 1-(prop-2-yn-1-ylamino)-2,3-dihydro-1H-indene-4-thiol derivatives as potent selective human monoamine oxidase B inhibitors: Design, SAR development, and biological evaluation. 2021 Jul 1 1
6 34290084 Monoamine Oxidase-B Inhibition Facilitates α-Synuclein Secretion In Vitro and Delays Its Aggregation in rAAV-Based Rat Models of Parkinson's Disease. 2021 Sep 1 1
7 34352710 Biphenylpiperazine Based MAO Inhibitors: Synthesis, Biological Evaluation, Reversibility and Molecular Modeling Studies. 2021 Oct 1
8 34562673 Discovery of 3,4-dichloro-N-(1H-indol-5-yl)benzamide: A highly potent, selective, and competitive hMAO-B inhibitor with high BBB permeability profile and neuroprotective action. 2021 Nov 1
9 34784871 How to optimize the effectiveness and safety of Parkinson's disease therapy? - a systematic review of drugs interactions with food and dietary supplements. 2021 Nov 16 1
10 32037726 Coumarin-Rasagiline Hybrids as Potent and Selective hMAO-B Inhibitors, Antioxidants, and Neuroprotective Agents. 2020 Mar 18 1
11 32250219 Exploring the Multifunctional Neuroprotective Promise of Rasagiline Derivatives for Multi-Dysfunctional Alzheimer's Disease. 2020 1
12 32378642 [Pharmacological properties and clinical efficacy of rasagiline mesylate (Azilect®)]. 2020 1
13 32652406 Design, synthesis and biological evaluation of rasagiline-clorgyline hybrids as novel dual inhibitors of monoamine oxidase-B and amyloid-β aggregation against Alzheimer's disease. 2020 Sep 15 1
14 32752896 Discovery of N-(1-(3-fluorobenzoyl)-1H-indol-5-yl)pyrazine-2-carboxamide: a novel, selective, and competitive indole-based lead inhibitor for human monoamine oxidase B. 2020 Dec 1
15 32858935 Hydride Abstraction as the Rate-Limiting Step of the Irreversible Inhibition of Monoamine Oxidase B by Rasagiline and Selegiline: A Computational Empirical Valence Bond Study. 2020 Aug 26 1
16 33375412 First Synthesis of Racemic Trans Propargylamino-Donepezil, a Pleiotrope Agent Able to Both Inhibit AChE and MAO-B, with Potential Interest against Alzheimer's Disease. 2020 Dec 27 1
17 30160213 Different Generations of Type-B Monoamine Oxidase Inhibitors in Parkinson's Disease: From Bench to Bedside. 2019 1
18 30192007 Rasagiline for amyotrophic lateral sclerosis: A randomized, controlled trial. 2019 Feb 2
19 30205936 Rasagiline monotherapy in early Parkinson's disease: A phase 3, randomized study in Japan. 2019 Mar 1
20 30689042 Long-term, open-label, phase 3 study of rasagiline in Japanese patients with early Parkinson's disease. 2019 Mar 1
21 30877626 Polycaprolactone-based neurotherapeutic delivery of rasagiline targeting behavioral and biochemical deficits in Parkinson's disease. 2019 Oct 1
22 31264403 Computational Insight into the Mechanism of the Irreversible Inhibition of Monoamine Oxidase Enzymes by the Antiparkinsonian Propargylamine Inhibitors Rasagiline and Selegiline. 2019 Aug 21 2
23 31421966 Rasagiline derivatives combined with histamine H3 receptor properties. 2019 Oct 1 2
24 31795034 Rasagiline, a monoamine oxidase B inhibitor, reduces in vivo [18F]THK5351 uptake in progressive supranuclear palsy. 2019 2
25 29159774 Pharmacokinetics, Pharmacodynamics, and Safety of Rasagiline Transdermal Patch: A Preliminary Study in Healthy Chinese Subjects. 2018 Feb 1
26 29279995 Type A and B monoamine oxidases distinctly modulate signal transduction pathway and gene expression to regulate brain function and survival of neurons. 2018 Nov 1
27 29339253 Design, synthesis and bioevalucation of novel 2,3-dihydro-1H-inden-1-amine derivatives as potent and selective human monoamine oxidase B inhibitors based on rasagiline. 2018 Feb 10 4
28 29417334 Pharmacological aspects of the neuroprotective effects of irreversible MAO-B inhibitors, selegiline and rasagiline, in Parkinson's disease. 2018 Nov 2
29 29464559 Monoamine Oxidases. 2018 1
30 29477356 Simultaneous controlled iontophoretic delivery of pramipexole and rasagiline in vitro and in vivo: Transdermal polypharmacy to treat Parkinson's disease. 2018 Jun 1
31 29748109 Efficacy and safety of adjunctive rasagiline in Japanese Parkinson's disease patients with wearing-off phenomena: A phase 2/3, randomized, double-blind, placebo-controlled, multicenter study. 2018 Aug 1
32 29847694 A multiple treatment comparison meta-analysis of monoamine oxidase type B inhibitors for Parkinson's disease. 2018 Sep 1
33 29955193 Interaction between Monoamine Oxidase B Inhibitors and Selective Serotonin Reuptake Inhibitors. 2018 May-Jun 1
34 29956417 Rasagiline, an inhibitor of MAO-B, decreases colonic motility through elevating colonic dopamine content. 2018 Nov 1
35 30341696 Monoamine oxidase inhibitors, and iron chelators in depressive illness and neurodegenerative diseases. 2018 Nov 1
36 30534374 Efficacy and safety of rasagiline in Chinese patients with early Parkinson's disease: a randomized, double-blind, parallel, placebo-controlled, fixed-dose study. 2018 1
37 28148284 Rasagiline-induced severe recurrent hypoglycemia in a young woman without diabetes: a case report. 2017 Feb 2 1
38 28293967 Efficacy of rasagiline for the treatment of Parkinson's disease: an updated meta-analysis. 2017 Aug 1
39 28299453 Simultaneous determination of MAO-A and -B activity following first time intake of an irreversible MAO-B inhibitor in patients with Parkinson's disease. 2017 Jun 1
40 28301816 MAO enzymes inhibitory activity of new benzimidazole derivatives including hydrazone and propargyl side chains. 2017 May 5 1
41 28550482 Efficacy of rasagiline and selegiline in Parkinson's disease: a head-to-head 3-year retrospective case-control study. 2017 Jun 2
42 28577058 Type B and A monoamine oxidase and their inhibitors regulate the gene expression of Bcl-2 and neurotrophic factors in human glioblastoma U118MG cells: different signal pathways for neuroprotection by selegiline and rasagiline. 2017 Sep 5
43 28682929 Determination of Monoamine Oxidase A and B Activity in Long-Term Treated Patients With Parkinson Disease. 2017 Sep/Oct 3
44 28923922 TrkB neurotrophic activities are blocked by α-synuclein, triggering dopaminergic cell death in Parkinson's disease. 2017 Oct 3 1
45 30566307 Anti-parkinsonian drugs today. 2017 Jan 1
46 25604428 Modulation of monoamine oxidase (MAO) expression in neuropsychiatric disorders: genetic and environmental factors involved in type A MAO expression. 2016 Feb 2
47 26897020 Erratum to: Prescribing pattern and resource utilization of monoamine oxidase-B inhibitors in Parkinson treatment: comparison between rasagiline and selegiline. 2016 Apr 1
48 27060436 Simultaneous bioanalysis of rasagiline and its major metabolites in human plasma by LC-MS/MS: Application to a clinical pharmacokinetic study. 2016 Jun 5 2
49 27089850 Free-water and BOLD imaging changes in Parkinson's disease patients chronically treated with a MAO-B inhibitor. 2016 Aug 1
50 27230855 PROSPERA: a randomized, controlled trial evaluating rasagiline in progressive supranuclear palsy. 2016 Aug 1