Urea

argininosuccinate synthase 1 ; Homo sapiens







34 Article(s)
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1 35016033 Citrulline depletion by ASS1 is required for proinflammatory macrophage activation and immune responses. 2022 Feb 3 1
2 32949613 Multi-omics analysis reveals that co-exposure to phthalates and metals disturbs urea cycle and choline metabolism. 2021 Jan 1
3 33478587 Intracellular arginine-dependent translation sensor reveals the dynamics of arginine starvation response and resistance in ASS1-negative cells. 2021 Jan 21 2
4 34606567 Anesthetic Management of a Patient With Citrullinemia Type I During Dental Treatment. 2021 Oct 1 1
5 34861885 ASS1 and ASL suppress growth in clear cell renal cell carcinoma via altered nitrogen metabolism. 2021 Dec 3 3
6 30573518 Acid-Induced Downregulation of ASS1 Contributes to the Maintenance of Intracellular pH in Cancer. 2019 Feb 1 3
7 31208364 Citrullinemia type I is associated with a novel splicing variant, c.773 + 4A > C, in ASS1: a case report and literature review. 2019 Jun 17 2
8 31784108 Type I Interferon Signaling Disrupts the Hepatic Urea Cycle and Alters Systemic Metabolism to Suppress T Cell Function. 2019 Dec 17 1
9 29247816 Generation of an ASS1 heterozygous knockout human embryonic stem cell line, WAe001-A-13, using CRISPR/Cas9. 2018 Jan 2
10 29754953 Arginase 2 Suppresses Renal Carcinoma Progression via Biosynthetic Cofactor Pyridoxal Phosphate Depletion and Increased Polyamine Toxicity. 2018 Jun 5 2
11 30108309 Sensitivity of Colorectal Cancer to Arginine Deprivation Therapy is Shaped by Differential Expression of Urea Cycle Enzymes. 2018 Aug 14 2
12 30155941 Recombinant human arginase induces apoptosis through oxidative stress and cell cycle arrest in small cell lung cancer. 2018 Nov 1
13 28097854 [Citrullinemia type I with recurrent liver failure in a child]. 2017 Feb 1 1
14 28587924 PRMT7 Interacts with ASS1 and Citrullinemia Mutations Disrupt the Interaction. 2017 Jul 21 1
15 28750687 Extracellular vesicles from human liver stem cells restore argininosuccinate synthase deficiency. 2017 Jul 27 3
16 27555199 General anesthesia in a patient with citrullinemia using Precedex as an adjunct to prevent delayed emergence. 2016 Sep 1
17 25634685 Effect of high-fat diet on hepatic proteomics of hamsters. 2015 Feb 18 1
18 26560030 Diversion of aspartate in ASS1-deficient tumours fosters de novo pyrimidine synthesis. 2015 Nov 19 5
19 24285724 Prognostic and therapeutic impact of argininosuccinate synthetase 1 control in bladder cancer as monitored longitudinally by PET imaging. 2014 Feb 1 3
20 25039902 Diagnosis and treatment of urea cycle disorder in Japan. 2014 Aug 1
21 24380022 Modulation of formation of the 3'-end of the human argininosuccinate synthetase mRNA by GT-repeat polymorphism. 2013 1
22 23430935 Molecular epidemiology of citrullinemia type I in a risk region of Argentina: a first step to preconception heterozygote detection. 2012 2
23 21494411 Argininosuccinate synthase: at the center of arginine metabolism. 2011 1
24 18666241 Genetic variation in the urea cycle: a model resource for investigating key candidate genes for common diseases. 2009 Jan 1
25 19217439 Evaluation of endogenous nitric oxide synthesis in congenital urea cycle enzyme defects. 2009 Mar 2
26 18840401 Identification of a liver-specific cAMP response element in the human argininosuccinate synthetase gene. 2008 Dec 5 2
27 16199199 Metabolic derangements in deficiency of citrin, a liver-type mitochondrial aspartate-glutamate carrier. 2005 Oct 2
28 12709047 Argininosuccinate synthetase from the urea cycle to the citrulline-NO cycle. 2003 May 3
29 12815590 Identification of 16 novel mutations in the argininosuccinate synthetase gene and genotype-phenotype correlation in 38 classical citrullinemia patients. 2003 Jul 1
30 10709858 The preferred source of arginine for high-output nitric oxide synthesis in blood vessels. 2000 Feb 2
31 8792870 Characterization of human wild-type and mutant argininosuccinate synthetase proteins expressed in bacterial cells. 1994-1995 1
32 1467433 Elevated gene expression of argininosuccinate synthetase in peripheral lymphocytes from systemic lupus erythematosus (SLE) patients. 1992 2
33 1568044 Lysinuric protein intolerance presenting deficiency of argininosuccinate synthetase. 1992 Jan 2
34 2235124 Development of ornithine metabolism in the mouse intestine. 1990 Sep 1