Nicotine

cytochrome P450, family 2, subfamily a, polypeptide 5 ; Mus musculus







13 Article(s)
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Pub. Year
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1 33375250 Postnatal Smoke Exposure Further Increases the Hepatic Nicotine Metabolism in Prenatally Smoke Exposed Male Offspring and Is Linked with Aberrant Cyp2a5 Methylation. 2020 Dec 26 1
2 30876690 Suppressed hepatocyte proliferation via a ROS-HNE-P21 pathway is associated with nicotine- and cotinine-enhanced alcoholic fatty liver in mice. 2019 Apr 23 1
3 30222954 Nicotine enhances alcoholic fatty liver in mice: Role of CYP2A5. 2018 Nov 1 12
4 28298240 Interstrain differences in the expression and activity of Cyp2a5 in the mouse liver. 2017 Mar 15 2
5 25998026 Altered cytochrome P450 activities and expression levels in the liver and intestines of the monosodium glutamate-induced mouse model of human obesity. 2015 Jul 15 1
6 24859605 Effects of methoxsalen, a CYP2A5/6 inhibitor, on nicotine dependence behaviors in mice. 2014 Oct 1
7 24045421 Impact of nicotine metabolism on nicotine's pharmacological effects and behavioral responses: insights from a Cyp2a(4/5)bgs-null mouse. 2013 Dec 1
8 21051534 Ethanol induction of CYP2A5: permissive role for CYP2E1. 2011 Feb 2
9 21395539 CYP2A5 induction and hepatocellular stress: an adaptive response to perturbations of heme homeostasis. 2011 Feb 1
10 19923441 Role of CYP2A5 in the clearance of nicotine and cotinine: insights from studies on a Cyp2a5-null mouse model. 2010 Feb 7
11 18098062 Nicotine metabolism and urinary elimination in mouse: in vitro and in vivo. 2008 Jan 1
12 17158199 Characterization and comparison of nicotine and cotinine metabolism in vitro and in vivo in DBA/2 and C57BL/6 mice. 2007 Mar 5
13 16485141 Nicotine self-administration in mice is associated with rates of nicotine inactivation by CYP2A5. 2006 Mar 9