8 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
1 | 21310277 | Dihydrofolate reductase deficiency due to a homozygous DHFR mutation causes megaloblastic anemia and cerebral folate deficiency leading to severe neurologic disease. | 2011 Feb 11 | 1 |
2 | 19666584 | Pivotal role of dihydrofolate reductase knockdown in the anticancer activity of 2-hydroxyoleic acid. | 2009 Aug 18 | 1 |
3 | 16712799 | Leucovorin-induced resistance against FDH growth suppressor effects occurs through DHFR up-regulation. | 2006 Jul 14 | 1 |
4 | 12467717 | Non-classical antifolates, 5-(N-phenylpyrrolidin-3-yl)-2,4,6-triaminopyrimidines and 2,4-Diamino-6(5H)-oxopyrimidines, synthesis and antitumor studies. | 2003 Jan 2 | 2 |
5 | 10499129 | Screening for inhibitors of dihydrofolate reductase using pulsed ultrafiltration mass spectrometry. | 1998 Apr | 1 |
6 | 7562910 | Effect of bridge region variation on antifolate and antitumor activity of classical 5-substituted 2,4-diaminofuro[2,3-d]pyrimidines. | 1995 Sep 15 | 1 |
7 | 2260989 | Mechanism of leucovorin reversal of methotrexate cytotoxicity in human MCF-7 breast cancer cells. | 1990 Dec 15 | 4 |
8 | 2448654 | Biochemical factors in the selectivity of leucovorin rescue: selective inhibition of leucovorin reactivation of dihydrofolate reductase and leucovorin utilization in purine and pyrimidine biosynthesis by methotrexate and dihydrofolate polyglutamates. | 1987 | 5 |