11 Article(s)Download |
PMID | Title | Pub. Year | #Total Relationships |
1 | 21206056 | Structural analysis of Pneumocystis carinii and human DHFR complexes with NADPH and a series of five potent 6-[5'-(ω-carboxyalkoxy)benzyl]pyrido[2,3-d]pyrimidine derivatives. | 2011 Jan | 2 |
2 | 17346178 | Dihydrofolate reductase as a target for chemotherapy in parasites. | 2007 | 2 |
3 | 12110313 | QSAR studies on biological activity of piritrexim analogues against pc DHFR. | 2002 Sep | 5 |
4 | 11996001 | Computer modeling studies of the structural role of NADPH binding to active site mutants of human dihydrofolate reductase in complex with piritrexim. | 2001 | 3 |
5 | 10683342 | Dihydrofolate reductase from Kaposi's sarcoma-associated herpesvirus. | 2000 Mar 1 | 1 |
6 | 7799402 | 2,4-Diamino-5-chloroquinazoline analogues of trimetrexate and piritrexim: synthesis and antifolate activity. | 1994 Dec 23 | 2 |
7 | 8431372 | Oral piritrexim, an effective treatment for metastatic urothelial cancer. | 1993 Feb | 3 |
8 | 2967669 | Potent antipneumocystis and antitoxoplasma activities of piritrexim, a lipid-soluble antifolate. | 1988 Apr | 2 |
9 | 3323908 | Initial clinical studies of piritrexim. | 1987 | 4 |
10 | 3431588 | Preclinical biochemical pharmacology and toxicology of piritrexim, a lipophilic inhibitor of dihydrofolate reductase. | 1987 | 1 |
11 | 7155133 | Metabolic inhibition by a new antifolate, 2,4-diamino-6-(2,5-dimethoxybenzyl)-5-methyl-pyrido[2,3-d]pyrimidine (BW3O1U), an effective inhibitor of human lymphoid and dihydrofolate reductase-overproducing mouse cell lines. | 1982 Nov | 1 |