| 1 |
34980160 | Bilirubin ameliorates murine atherosclerosis through inhibiting cholesterol synthesis and reshaping the immune system. | 2022 Jan 3 |
2 |
| 2 |
35184357 | Targeted inhibition of PPARα ameliorates CLA-induced hypercholesterolemia via hepatic cholesterol biosynthesis reprogramming. | 2022 Jun |
1 |
| 3 |
35428331 | L-Arabinose improves hypercholesterolemia via regulating bile acid metabolism in high-fat-high-sucrose diet-fed mice. | 2022 Apr 15 |
2 |
| 4 |
35562083 | Defective AMPK regulation of cholesterol metabolism accelerates atherosclerosis by promoting HSPC mobilization and myelopoiesis. | 2022 Jul |
1 |
| 5 |
33222146 | Simvastatin Enhances Muscle Regeneration Through Autophagic Defect-Mediated Inflammation and mTOR Activation in G93ASOD1 Mice. | 2021 Apr |
1 |
| 6 |
33483533 | Genetic deletion of Abcc6 disturbs cholesterol homeostasis in mice. | 2021 Jan 22 |
3 |
| 7 |
33650825 | Impact of Methyl-β-Cyclodextrin and Apolipoprotein A-I on The Expression of ATP-Binding Cassette Transporter A1 and Cholesterol Depletion in C57BL/6 Mice Astrocytes. | 2021 Apr |
1 |
| 8 |
33740503 | Acetaldehyde Dehydrogenase 2 regulates HMG-CoA reductase stability and cholesterol synthesis in the liver. | 2021 May |
4 |
| 9 |
33905408 | HMGCR inhibition stabilizes the glycolytic enzyme PKM2 to support the growth of renal cell carcinoma. | 2021 Apr |
2 |
| 10 |
34258925 | RNA-binding protein hnRNPR reduces neuronal cholesterol levels by binding to and suppressing HMGCR. | 2021 Jun 30 |
1 |
| 11 |
34286573 | Novel Metabolic Regulation of Bile Acid Responses to Low Cholesterol in Whole-Grain-Diet-Fed Mice. | 2021 Aug 4 |
2 |
| 12 |
34431998 | LH Induces De Novo Cholesterol Biosynthesis via SREBP Activation in Granulosa Cells During Ovulation in Female Mice. | 2021 Nov 1 |
2 |
| 13 |
34600072 | SIRT-1 Activity Sustains Cholesterol Synthesis in the Brain. | 2021 Nov 10 |
1 |
| 14 |
34626855 | The hepatocyte IKK:NF-κB axis promotes liver steatosis by stimulating de novo lipogenesis and cholesterol synthesis. | 2021 Dec |
2 |
| 15 |
31058344 | Simvastatin enhances chemotherapy in cervical cancer via inhibition of multiple prenylation-dependent GTPases-regulated pathways. | 2020 Feb |
1 |
| 16 |
31690648 | Myeloid HMG-CoA Reductase Determines Adipose Tissue Inflammation, Insulin Resistance, and Hepatic Steatosis in Diet-Induced Obese Mice. | 2020 Feb |
2 |
| 17 |
31968646 | Chitooligosaccharides Modulate Glucose-Lipid Metabolism by Suppressing SMYD3 Pathways and Regulating Gut Microflora. | 2020 Jan 20 |
2 |
| 18 |
32071155 | MicroRNA 27a Is a Key Modulator of Cholesterol Biosynthesis. | 2020 Apr 13 |
1 |
| 19 |
32118581 | Enhanced ER-associated degradation of HMG CoA reductase causes embryonic lethality associated with Ubiad1 deficiency. | 2020 Mar 2 |
2 |
| 20 |
32250344 | Parental metabolic syndrome epigenetically reprograms offspring hepatic lipid metabolism in mice. | 2020 May 1 |
2 |
| 21 |
32528976 | LDL Receptor Pathway Regulation by miR-224 and miR-520d. | 2020 |
1 |
| 22 |
32976883 | NPY stimulates cholesterol synthesis acutely by activating the SREBP2-HMGCR pathway through the Y1 and Y5 receptors in murine hepatocytes. | 2020 Dec 1 |
1 |
| 23 |
33050202 | The Crucial Role of Xanthine Oxidase in CKD Progression Associated with Hypercholesterolemia. | 2020 Oct 9 |
1 |
| 24 |
33177714 | Feeding induces cholesterol biosynthesis via the mTORC1-USP20-HMGCR axis. | 2020 Dec |
4 |
| 25 |
33274012 | Quinovic Acid Impedes Cholesterol Dyshomeostasis, Oxidative Stress, and Neurodegeneration in an Amyloid-β-Induced Mouse Model. | 2020 |
2 |
| 26 |
33363473 | Cis- and Trans-Palmitoleic Acid Isomers Regulate Cholesterol Metabolism in Different Ways. | 2020 |
1 |
| 27 |
33424933 | Sleep Disturbance Induces Increased Cholesterol Level by NR1D1 Mediated CYP7A1 Inhibition. | 2020 |
1 |
| 28 |
30169110 | Atorvastatin, but not pravastatin, inhibits cardiac Akt/mTOR signaling and disturbs mitochondrial ultrastructure in cardiac myocytes. | 2019 Jan |
1 |
| 29 |
30384071 | Pubertal exposure to the endocrine disruptor mono-2-ethylhexyl ester at body burden level caused cholesterol imbalance in mice. | 2019 Jan |
2 |
| 30 |
30504232 | Hepatic transcriptome analysis from HFD-fed mice defines a long noncoding RNA regulating cellular cholesterol levels. | 2019 Feb |
2 |
| 31 |
30592221 | Hypocholesterolemic Effect of the Lignin-Rich Insoluble Residue of Brewer's Spent Grain in Mice Fed a High-Fat Diet. | 2019 Jan 30 |
1 |
| 32 |
30609251 | Reactive oxygen species-induced changes in glucose and lipid metabolism contribute to the accumulation of cholesterol in the liver during aging. | 2019 Apr |
1 |
| 33 |
30619997 | Inhibition of Adenosine Monophosphate-Activated Protein Kinase-3-Hydroxy-3-Methylglutaryl Coenzyme A Reductase Signaling Leads to Hypercholesterolemia and Promotes Hepatic Steatosis and Insulin Resistance. | 2019 Jan |
3 |
| 34 |
30700846 | Anti-cancer effect of doxorubicin is mediated by downregulation of HMG-Co A reductase via inhibition of EGFR/Src pathway. | 2019 Jul |
1 |
| 35 |
30785396 | Schnyder corneal dystrophy-associated UBIAD1 inhibits ER-associated degradation of HMG CoA reductase in mice. | 2019 Feb 20 |
2 |
| 36 |
30821074 | A functional interaction between Hippo-YAP signalling and SREBPs mediates hepatic steatosis in diabetic mice. | 2019 May |
1 |
| 37 |
30882716 | Treadmill exercise inhibits amyloid-β generation in the hippocampus of APP/PS1 transgenic mice by reducing cholesterol-mediated lipid raft formation. | 2019 May 1 |
1 |
| 38 |
30953750 | Elimination of adrenocortical apolipoprotein E production does not impact glucocorticoid output in wild-type mice. | 2019 Jun 15 |
1 |
| 39 |
31472226 | Red raspberry extract (Rubus idaeus L shrub) intake ameliorates hyperlipidemia in HFD-induced mice through PPAR signaling pathway. | 2019 Nov |
1 |
| 40 |
31670354 | Whole barley prevents obesity and dyslipidemia without the involvement of the gut microbiota in germ free C57BL/6J obese mice. | 2019 Nov 1 |
3 |
| 41 |
31676775 | Characterizing the Role of HMG-CoA Reductase in Aryl Hydrocarbon Receptor-Mediated Liver Injury in C57BL/6 Mice. | 2019 Nov 1 |
5 |
| 42 |
29278865 | Simvastatin activates single skeletal RyR1 channels but exerts more complex regulation of the cardiac RyR2 isoform. | 2018 Mar |
1 |
| 43 |
29678744 | Long noncoding RNA lncARSR promotes hepatic cholesterol biosynthesis via modulating Akt/SREBP-2/HMGCR pathway. | 2018 Jun 15 |
6 |
| 44 |
29738536 | Statins impact primary embryonic mouse neural stem cell survival, cell death, and fate through distinct mechanisms. | 2018 |
1 |
| 45 |
29853881 | Beta-Arrestin 1 Mediates Liver Thyrotropin Regulation of Cholesterol Conversion Metabolism via the Akt-Dependent Pathway. | 2018 |
1 |
| 46 |
30310412 | Protective Effects of Yinchenhao Decoction on Cholesterol Gallstone in Mice Fed a Lithogenic Diet by Regulating LXR, CYP7A1, CYP7B1, and HMGCR Pathways. | 2018 |
1 |
| 47 |
30354246 | Myeloid HMG-CoA (3-Hydroxy-3-Methylglutaryl-Coenzyme A) Reductase Determines Atherosclerosis by Modulating Migration of Macrophages. | 2018 Nov |
2 |
| 48 |
30400147 | Effects of Metformin Combined with Lactoferrin on Lipid Accumulation and Metabolism in Mice Fed with High-Fat Diet. | 2018 Nov 2 |
1 |
| 49 |
30401401 | Graft Protective Effect of HMG-CoA Reductase Inhibitor Pravastatin in Murine Cardiac Allograft Transplantation. | 2018 Nov |
1 |
| 50 |
28112179 | Dicer1/miR-29/HMGCR axis contributes to hepatic free cholesterol accumulation in mouse non-alcoholic steatohepatitis. | 2017 May |
4 |