4-oxofenretinide

haptoglobin-related protein ; Homo sapiens







8 Article(s)
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1 28448568 Inhibitory effects of fenretinide metabolites N-[4-methoxyphenyl]retinamide (MPR) and 4-oxo-N-(4-hydroxyphenyl)retinamide (3-keto-HPR) on fenretinide molecular targets β-carotene oxygenase 1, stearoyl-CoA desaturase 1 and dihydroceramide Δ4-desaturase 1. 2017 1
2 27135197 Water-soluble derivatives of 4-oxo-N-(4-hydroxyphenyl) retinamide: synthesis and biological activity. 2016 Oct 1
3 21543327 Identification of dihydroceramide desaturase as a direct in vitro target for fenretinide. 2011 Jul 15 3
4 20976277 4-oxo-N-(4-hydroxyphenyl)retinamide: two independent ways to kill cancer cells. 2010 Oct 14 3
5 19996280 Antimitotic effect of the retinoid 4-oxo-fenretinide through inhibition of tubulin polymerization: a novel mechanism of retinoid growth-inhibitory activity. 2009 Dec 3
6 18066548 Pharmacokinetics of oral fenretinide in neuroblastoma patients: indications for optimal dose and dosing schedule also with respect to the active metabolite 4-oxo-fenretinide. 2008 Sep 1
7 16540676 4-oxo-fenretinide, a recently identified fenretinide metabolite, induces marked G2-M cell cycle arrest and apoptosis in fenretinide-sensitive and fenretinide-resistant cell lines. 2006 Mar 15 2
8 15448016 Identification of the fenretinide metabolite 4-oxo-fenretinide present in human plasma and formed in human ovarian carcinoma cells through induction of cytochrome P450 26A1. 2004 Sep 15 2