Reactive Oxygen Species

haptoglobin-related protein ; Homo sapiens







30 Article(s)
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1 27367907 Fenretinide (4-HPR) Targets Caspase-9, ERK 1/2 and the Wnt3a/β-Catenin Pathway in Medulloblastoma Cells and Medulloblastoma Cell Spheroids. 2016 1
2 25313218 The bioactive lipid 4-hydroxyphenyl retinamide inhibits flavivirus replication. 2015 Jan 1
3 25576804 Colloidal silver nanoparticles improve anti-leukemic drug efficacy via amplification of oxidative stress. 2015 Feb 1 1
4 24253178 p75 neurotrophin receptor and fenretinide-induced signaling in neuroblastoma. 2014 Feb 1
5 24392637 The oxidation states of DJ-1 dictate the cell fate in response to oxidative stress triggered by 4-hpr: autophagy or apoptosis? 2014 Oct 1 5
6 22428532 Dihydroceramide accumulation and reactive oxygen species are distinct and nonessential events in 4-HPR-mediated leukemia cell death. 2012 Apr 5
7 22532987 Fenretinide cytotoxicity is independent of both constitutive and pharmacologically modulated glutathione levels in pediatric acute lymphoblastic leukemia cells cultured at hypoxia. 2012 Jun 1
8 22761939 AF1q: a novel mediator of basal and 4-HPR-induced apoptosis in ovarian cancer cells. 2012 2
9 21072519 Cytotoxic responses to N-(4-hydroxyphenyl)retinamide in human pancreatic cancer cells. 2011 Aug 2
10 21557271 Inhibition of acid ceramidase by a 2-substituted aminoethanol amide synergistically sensitizes prostate cancer cells to N-(4-hydroxyphenyl) retinamide. 2011 Jul 2
11 21723035 TMEM14A inhibits N-(4-hydroxyphenyl)retinamide-induced apoptosis through the stabilization of mitochondrial membrane potential. 2011 Oct 28 1
12 20976277 4-oxo-N-(4-hydroxyphenyl)retinamide: two independent ways to kill cancer cells. 2010 Oct 14 2
13 19041174 Identification of ADP-ribosylation factor 4 as a suppressor of N-(4-hydroxyphenyl)retinamide-induced cell death. 2009 Apr 8 2
14 19421858 Selective apoptosis induction by the cancer chemopreventive agent N-(4-hydroxyphenyl)retinamide is achieved by modulating mitochondrial bioenergetics in premalignant and malignant human prostate epithelial cells. 2009 Jul 2
15 18398104 Mechanism of synergy of N-(4-hydroxyphenyl)retinamide and ABT-737 in acute lymphoblastic leukemia cell lines: Mcl-1 inactivation. 2008 Apr 16 4
16 18425327 Pleiotropic effects of fenretinide in neuroblastoma cell lines and multicellular tumor spheroids. 2008 May 2
17 17454142 4-HPR-mediated leukemia cell cytotoxicity is triggered by ceramide-induced mitochondrial oxidative stress and is regulated downstream by Bcl-2. 2007 May 2
18 16407847 N-(4-hydroxyphenyl)retinamide-induced apoptosis triggered by reactive oxygen species is mediated by activation of MAPKs in head and neck squamous carcinoma cells. 2006 May 4 1
19 16540676 4-oxo-fenretinide, a recently identified fenretinide metabolite, induces marked G2-M cell cycle arrest and apoptosis in fenretinide-sensitive and fenretinide-resistant cell lines. 2006 Mar 15 1
20 16077929 Increased level of the p67phox subunit of NADPH oxidase by 4HPR in head and neck squamous carcinoma cells. 2005 Sep 1
21 16124896 [The role of reactive oxygen species in N-[4-hydroxyphenyl] retinamide induced apoptosis in bladder cancer cell lineT24]. 2005 Jun 2
22 16158929 Intracellular glutathione levels determine cell sensitivity to apoptosis induced by the antineoplasic agent N-(4-hydroxyphenyl) retinamide. 2005 May-Jun 3
23 16403262 [Mechanisms of fenretinide-triggered apoptosis in leukemic cells]. 2005 Dec 3
24 13679861 The chemopreventive agent N-(4-hydroxyphenyl)retinamide induces apoptosis through a mitochondrial pathway regulated by proteins from the Bcl-2 family. 2003 Sep 18 1
25 14604280 N-(4-Hydroxyphenyl)retinamide (4-HPR) induces leukemia cell death via generation of reactive oxygen species. 2003 Oct 9
26 11807954 Modulation of cyclophilin gene expression by N-4-(hydroxyphenyl)retinamide: association with reactive oxygen species generation and apoptosis. 2002 Jan 1
27 11986953 N-(4-hydroxyphenyl)retinamide increases ceramide and is cytotoxic to acute lymphoblastic leukemia cell lines, but not to non-malignant lymphocytes. 2002 May 1
28 10706389 Antioxidant properties of N-(4-hydroxyphenyl)retinamide (fenretinide). 2000 Feb 1
29 10344763 Mediation of N-(4-hydoxyphenyl)retinamide-induced apoptosis in human cancer cells by different mechanisms. 1999 May 15 1
30 10393722 Increase of ceramide and induction of mixed apoptosis/necrosis by N-(4-hydroxyphenyl)- retinamide in neuroblastoma cell lines. 1999 Jul 7 2