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O-6-methylguanine-DNA methyltransferase ; Homo sapiens







28 Article(s)
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1 29744991 Rapid Electrochemical Assessment of Tumor Suppressor Gene Methylations in Raw Human Serum and Tumor Cells and Tissues Using Immunomagnetic Beads and Selective DNA Hybridization. 2018 Jul 2 1
2 27542245 Validation of the high-performance of pyrosequencing for clinical MGMT testing on a cohort of glioblastoma patients from a prospective dedicated multicentric trial. 2016 Sep 20 1
3 24748501 Predictive value of CHFR and MLH1 methylation in human gastric cancer. 2015 Apr 1
4 25755756 Detection of MGMT promoter methylation in glioblastoma using pyrosequencing. 2015 1
5 25973069 Detection of MGMT promoter methylation in glioblastoma using pyrosequencing. 2015 1
6 23993306 A simple quantitative diagnostic alternative for MGMT DNA-methylation testing on RCL2 fixed paraffin embedded tumors using restriction coupled qPCR. 2014 Jan-Feb 1
7 24709436 Prevalence and clinicopathologic correlates of O⁶-methylguanine-DNA methyltransferase methylation status in patients with triple-negative breast cancer treated preoperatively by alkylating drugs. 2014 Aug 1
8 26150933 Determining methylation status of methylguanine DNA methyl transferase (MGMT) from formalin-fixed, paraffin embedded tumor tissue. 2014 2
9 21792731 O⁶-methylguanine-DNA-methyltransferase promoter methylation assessment by microdissection-assisted methylation-specific PCR and high resolution melting analysis in patients with glioblastomas. 2012 Jan 2
10 21922591 The hypermethylation of the O6-methylguanine-DNA methyltransferase gene promoter in gliomas--correlation with array comparative genome hybridization results and IDH1 mutation. 2012 Jan 1
11 22228432 Methylation of O6-methylguanine-DNA methyltransferase (MGMT) promoter gene in triple-negative breast cancer patients. 2012 Jul 1
12 22665686 Pseudoprogression of malignant glioma in Chinese patients receiving concomitant chemoradiotherapy. 2012 Jun 1
13 22986464 O6-Methylguanine-DNA methyltransferase is a novel negative effector of invasion in glioblastoma multiforme. 2012 Nov 2
14 20556478 O6-methylguanine DNA methyltransferase status determined by promoter methylation and immunohistochemistry in gliosarcoma and their clinical implications. 2011 Feb 1
15 21181234 Primer extension based quantitative polymerase chain reaction reveals consistent differences in the methylation status of the MGMT promoter in diffusely infiltrating gliomas (WHO grade II-IV) of adults. 2011 Aug 1
16 19656999 MGMT promoter hypermethylation in a series of 104 glioblastomas. 2009 Jul-Aug 2
17 18556773 Validation of real-time methylation-specific PCR to determine O6-methylguanine-DNA methyltransferase gene promoter methylation in glioma. 2008 Jul 1
18 19130735 Reliability and reproducibility of PCR-based testing of O6-methylguanine-DNA methyltransferase gene (MGMT) promoter methylation status in formalin-fixed and paraffin-embedded neurosurgical biopsy specimens. 2008 Nov-Dec 3
19 17260000 A simplified laboratory validated assay for MGMT promoter hypermethylation analysis of glioma specimens from formalin-fixed paraffin-embedded tissue. 2007 Apr 2
20 17591937 Optimization of quantitative MGMT promoter methylation analysis using pyrosequencing and combined bisulfite restriction analysis. 2007 Jul 1
21 17650424 [Promoter methylation of several tumor suppressor genes in human gastric adenocarcinoma]. 2007 Apr 10 1
22 18069630 [Frequent promoter hypermethylation of several tumor suppressor genes in gastric carcinoma and foveolar epithelium]. 2007 Jul 1
23 16541434 Progressive low-grade oligodendrogliomas: response to temozolomide and correlation between genetic profile and O6-methylguanine DNA methyltransferase protein expression. 2006 Apr 15 1
24 15915369 Tumor progression through epigenetic gene silencing of O(6)-methylguanine-DNA methyltransferase in human biliary tract cancers. 2005 May 1
25 12579307 In situ detection of O6-methylguanine-DNA methyltransferase messenger RNA in paraffin-embedded human astrocytic tumor tissues by nested in situ RT-PCR is useful in predicting chemotherapy-resistance of tumors. 2003 Mar 1
26 11776495 Expression and prognostic significance of O6-methylguanine-DNA methyltransferase in hepatocellular, gastric, and breast cancers. 2001 Dec 1
27 9605190 Immunohistochemical detection of the DNA repair enzyme O6-methylguanine-DNA methyltransferase in formalin-fixed, paraffin-embedded astrocytomas. 1998 May 1
28 1547538 In situ hybridization of human kidney tissue reveals cell-type-specific expression of the O6-methylguanine-DNA methyltransferase gene. 1992 Mar 2