Nitrosourea Compounds

O-6-methylguanine-DNA methyltransferase ; Homo sapiens







16 Article(s)
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Pub. Year
#Total Relationships
1 34808283 Molecular tests for prediction of tumor sensitivity to cytotoxic drugs. 2022 Feb 1 1
2 31039537 DNA repair in personalized brain cancer therapy with temozolomide and nitrosoureas. 2019 Jun 1
3 23761053 Antitumor activity of semisynthetic derivatives of Aconitum alkaloids. 2014 Feb 1
4 17695447 A methionine-free diet associated with nitrosourea treatment down-regulates methylguanine-DNA methyl transferase activity in patients with metastatic cancer. 2007 Jul-Aug 1
5 17825378 Prognostic significance of loss of O6-methylguanine-DNA methyltransferase expression in supratentorial diffuse low-grade astrocytoma. 2007 Dec 1
6 18156172 Prognostic significance of O6-methylguanine-DNA methyltransferase protein expression in patients with recurrent glioblastoma treated with temozolomide. 2007 Dec 1
7 16039682 O(6)-methylguanine DNA-methyltransferase (MGMT) overexpression in melanoma cells induces resistance to nitrosoureas and temozolomide but sensitizes to mitomycin C. 2006 Mar 1 2
8 16936459 Preliminary individualized chemotherapy for malignant astrocytomas based on O6-methylguanine-deoxyribonucleic acid methyltransferase methylation analysis. 2006 Aug 2
9 15455376 O6-methylguanine-DNA methyltransferase methylation and TP53 mutation in malignant astrocytomas and their relationships with clinical course. 2005 Feb 10 1
10 15853207 [Resent advances in chemotherapy for malignant brain tumors]. 2005 Apr 3
11 15662974 Immunohistochemical study for O6-methylguanine-DNA methyltransferase in the non-neoplastic and neoplastic components of gliomas. 2004 Dec 2
12 12739231 Relationship between expression of O6-methylguanine-DNA methyltransferase, glutathione-S-transferase pi in glioblastoma and the survival of the patients treated with nimustine hydrochloride: an immunohistochemical analysis. 2003 Apr 2
13 11778552 [Mutation of human O6-alkylguanine-DNA alkyltransferase confers resistance to O6-benzylguanine]. 2000 Jul 1
14 9779706 Correlation of tumor O6 methylguanine-DNA methyltransferase levels with survival of malignant astrocytoma patients treated with bis-chloroethylnitrosourea: a Southwest Oncology Group study. 1998 Oct 1
15 9271436 Methylation of discrete regions of the O6-methylguanine DNA methyltransferase (MGMT) CpG island is associated with heterochromatinization of the MGMT transcription start site and silencing of the gene. 1997 Sep 1
16 8364257 Identification of nitrosourea-resistant human rhabdomyosarcomas by in situ immunostaining of O6-methylguanine-DNA methyltransferase. 1993 1