telcagepant

calcitonin related polypeptide alpha ; Homo sapiens







12 Article(s)
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1 22816019 ACS chemical neuroscience molecule spotlight on Telcagepant (MK-0974). 2011 Jul 20 2
2 19914210 Non-peptidic antagonists of the CGRP receptor, BIBN4096BS and MK-0974, interact with the calcitonin receptor-like receptor via methionine-42 and RAMP1 via tryptophan-74. 2010 Jan 1 1
3 20078608 Inhibition of capsaicin-induced increase in dermal blood flow by the oral CGRP receptor antagonist, telcagepant (MK-0974). 2010 Jan 2
4 20573757 Characterization of the calcitonin gene-related peptide receptor antagonist telcagepant (MK-0974) in human isolated coronary arteries. 2010 Sep 1 1
5 19084002 Examining the binding properties of MK-0974: a CGRP receptor antagonist for the acute treatment of migraine. 2009 Jan 14 4
6 17914062 Randomized controlled trial of an oral CGRP receptor antagonist, MK-0974, in acute treatment of migraine. 2008 Apr 15 5
7 18039958 Pharmacological characterization of MK-0974 [N-[(3R,6S)-6-(2,3-difluorophenyl)-2-oxo-1-(2,2,2-trifluoroethyl)azepan-3-yl]-4-(2-oxo-2,3-dihydro-1H-imidazo[4,5-b]pyridin-1-yl)piperidine-1-carboxamide], a potent and orally active calcitonin gene-related peptide receptor antagonist for the treatment of migraine. 2008 Feb 4
8 18217201 Treatment of migraine attacks based on the interaction with the trigemino-cerebrovascular system. 2008 Feb 1
9 18759547 Proinflammatory mediators and migraine pathogenesis: moving towards CGRP as a target for a novel therapeutic class. 2008 Sep 1
10 18991732 The tortuous road to an ideal CGRP function blocker for the treatment of migraine. 2008 2
11 19036425 Efficacy and tolerability of MK-0974 (telcagepant), a new oral antagonist of calcitonin gene-related peptide receptor, compared with zolmitriptan for acute migraine: a randomised, placebo-controlled, parallel-treatment trial. 2008 Dec 20 1
12 17963849 CGRP antagonists: unravelling the role of CGRP in migraine. 2007 Nov 1