Heparin

coagulation factor II ; Rattus norvegicus







60 Article(s)
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1 32153221 Monitoring Compound-Related Effects on Coagulability in Rats and Cynomolgus and Rhesus Monkeys by Thrombin Generation Kinetic Measurement. 2020 May/Jun 3
2 31157200 Supramolecular Aptamers on Graphene Oxide for Efficient Inhibition of Thrombin Activity. 2019 1
3 24692161 Intratracheal heparin improves plastic bronchitis due to sulfur mustard analog. 2015 Feb 1
4 22914811 Bivalirudin utilization in rats undergoing cardiopulmonary bypass: preventing the increase of antiheparin/platelet factor 4 antibody in perioperative period. 2014 Mar 1
5 23200896 Antithrombotic and anticoagulant effects of direct factor Xa inhibitor darexaban in rat and rabbit models of venous thrombosis. 2013 Jan 15 1
6 23494756 Antifibrotic effect of heparin on liver fibrosis model in rats. 2012 Dec 6 3
7 19886733 Heparin-conjugated fibrin as an injectable system for sustained delivery of bone morphogenetic protein-2. 2010 Apr 2
8 20010091 Cooperative antithrombotic effect from the simultaneous inhibition of thrombin and factor Xa. 2010 Mar 1
9 20381830 Higher specificity of the activity of low molecular weight fucoidan for thrombin-induced platelet aggregation. 2010 May 1
10 19925675 Topical recombinant thrombin at a concentration of 1000 IU/mL reliably shortens in vivo TTH and delivers durable hemostasis in the presence of heparin anticoagulation and clopidogrel platelet inhibition in a rabbit model of vascular bleeding. 2009 Nov 19 8
11 18310767 Low molecular weight heparin impairs tendon repair. 2008 Mar 2
12 18315554 Recombinant human factor VIIa and a factor VIIa-analogue reduces heparin and low molecular weight heparin (LMWH)-induced bleeding in rats. 2008 May 1
13 17264724 Effect of combined anticoagulation using heparin and bivalirudin on the hemostatic and inflammatory responses to cardiopulmonary bypass in the rat. 2007 Feb 1
14 16373349 3-O-sulfated oligosaccharide structures are recognized by anti-heparan sulfate antibody HS4C3. 2006 Feb 24 1
15 15988269 The effect of tirofiban on microvascular thrombosis: crush model. 2005 Jul 1
16 15253248 Inhibition of intimal hyperplasia by direct thrombin inhibitors in an animal vein bypass model. 2004 Mar 1
17 12540482 Effect of covalent serpin-heparinoid complexes on plasma thrombin generation on fetal distal lung epithelium. 2003 Feb 1
18 11751276 Coordinate expression of anticoagulant heparan sulfate proteoglycans and serine protease inhibitors in the rat ovary: a potent system of proteolysis control. 2002 Jan 1
19 11858483 Effect of new synthetic heparin mimetics on whole blood thrombin generation in vivo and in vitro in rats. 2002 Feb 2
20 10903991 Heparin blockade of thrombin-induced smooth muscle cell migration involves inhibition of epidermal growth factor (EGF) receptor transactivation by heparin-binding EGF-like growth factor. 2000 Jul 21 3
21 10959702 Activity of a sub-cutaneously administered novel mixed micellar formulation of argatroban in rat and rabbit models of venous thrombosis. 2000 Aug 1
22 10977903 Activation of rat mast cells upon stimulation of protease-activated receptor (PAR-1). 2000 Apr 2
23 10404775 Effect of clopidogrel on thrombin generation in platelet-rich plasma in the rat. 1999 Jun 2
24 9493603 BCH-2763, a novel potent parenteral thrombin inhibitor, is an effective antithrombotic agent in rodent models of arterial and venous thrombosis--comparisons with heparin, r-hirudin, hirulog, inogatran and argatroban. 1998 Feb 1
25 9535876 Localization of the thrombin-binding domain on prothrombin fragment 2. 1998 Apr 10 1
26 9609730 Effect of a novel covalent antithrombin-heparin complex on thrombin generation on fetal distal lung epithelium. 1998 Jun 1
27 9653887 Relationship between the antithrombotic effect of YM-75466, a novel factor Xa inhibitor, and coagulation parameters in rats. 1998 Apr 24 1
28 9836771 Role of blood clot formation on early edema development after experimental intracerebral hemorrhage. 1998 Dec 2
29 9245569 The regulation of p42/p44 mitogen-activated protein kinases in the injured rat carotid artery. 1997 Jul 1 1
30 8903462 Thrombin is a distal mediator of lipopolysaccharide-induced liver injury in the rat. 1996 Oct 1
31 7851376 Identification of the proteolytic thrombin fragments formed after cleavage with rat mast cell protease 1. 1995 Jan 15 1
32 7530156 Two sites (23-30, 76-90) on rat P-selectin mediate thrombin activated platelet-neutrophil interactions. 1994 Dec 1
33 8182050 Interaction of heparin with rat mast cell protease 1. 1994 May 20 1
34 7682732 Investigation of long-term hypocoagulability in rats after intratracheal administration of unfractionated heparin. 1993 Feb 1 1
35 8218851 Plasma kallikrein and thrombin are cleared through unrelated hepatic pathways. 1993 Aug 3
36 8225173 [Effects of platelet aggregating inhibitor on pulmonary metastases of tumor cells after surgical resection]. 1993 Sep 1
37 8243716 [Role of catecholamines, released due to stress, on stimulation of heparin secretion by mast cells in rats]. 1993 Jul-Aug 2
38 8281931 Participation in cellular prostaglandin synthesis of type-II phospholipase A2 secreted and anchored on cell-surface heparan sulfate proteoglycan. 1993 Dec 15 2
39 8446937 Effect of heparin on thrombin inhibition in the microcirculation. 1993 Jan 11 4
40 1375562 Aprotinin: the ideal anti-coagulant? 1992 May 2
41 1441296 [Participation of protein C in reaction of the anti-coagulant system to intravenous administration of thrombin and thromboplastin to rats]. 1992 Jan-Feb 1
42 1666391 [Pharmacological studies of low molecular weight heparin (LHG)]. 1991 Oct 2
43 1787232 [The blood anticoagulant system in rats perorally administered a heparin-acetylsalicylic acid complex]. 1991 Jul-Aug 1
44 1854945 [The effect of heparin and thromboplastin on the half-life of 125I-protein C in the blood flow of rats]. 1991 Feb 1
45 2466498 [Alpha-thrombin stimulation of heparin secretion by the peritoneal mast cells in rats]. 1989 Feb 5
46 3181520 [Effect of a complex mixture of plasma proteins with heparin on the anticoagulation and fibrinolytic activity of the blood plasma in animals following intravenous administration of tissue thromboplastin]. 1988 Jun 1
47 3428717 Effect of heparin, hirudin, and a synthetic thrombin inhibitor on antithrombin III in thrombin-induced disseminated intravascular coagulation in rats. 1987 2
48 3481660 Time courses of the antithrombotic effects, bleeding enhancing effects and interactions with factors Xa and thrombin after administration of low molecular weight heparinoid Org 10172 or heparin to rats. 1987 Dec 1 3
49 3597343 Purification and characterization of phospholipase A2 released from rat platelets. 1987 Mar 1
50 3014736 [Heparin-induced impairment of thrombin interaction with fibrinogen and receptors of the anti-coagulation system]. 1986 May-Jun 5