Tyrosine

protein tyrosine kinase 2 beta ; Rattus norvegicus







55 Article(s)
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1 31676368 Muscarinic receptor stimulation induces TASK1 channel endocytosis through a PKC-Pyk2-Src pathway in PC12 cells. 2020 Jan 1
2 32391653 Acute stress induces visceral hypersensitivity via glucocorticoid receptor-mediated membrane insertion of TRPM8: Involvement of a non-receptor tyrosine kinase Pyk2. 2020 Oct 1
3 24718602 Tyrosine 402 phosphorylation of Pyk2 is involved in ionomycin-induced neurotransmitter release. 2014 3
4 25347863 PYK2 selectively mediates signals for growth versus differentiation in response to stretch of spontaneously active vascular smooth muscle. 2014 Jul 16 1
5 20071509 Postsynaptic clustering and activation of Pyk2 by PSD-95. 2010 Jan 13 1
6 17684059 Calcineurin is essential for depolarization-induced nuclear translocation and tyrosine phosphorylation of PYK2 in neurons. 2007 Sep 1 3
7 16199135 RAFTK/Pyk2 mediates LPA-induced PC12 cell migration. 2006 Jul 1
8 16877402 Roles of protein kinase C, Ca2+, Pyk2, and c-Src in agonist activation of rat lacrimal gland p42/p44 MAPK. 2006 Aug 2
9 15537634 Depolarization activates ERK and proline-rich tyrosine kinase 2 (PYK2) independently in different cellular compartments in hippocampal slices. 2005 Jan 7 1
10 15705590 Implication of phospholipase D2 in oxidant-induced phosphoinositide 3-kinase signaling via Pyk2 activation in PC12 cells. 2005 Apr 22 4
11 15748156 Changes in phosphorylation of the NMDA receptor in the rat hippocampus induced by status epilepticus. 2005 Mar 1
12 15814199 Suppression of Pyk2 attenuated the increased tyrosine phosphorylation of NMDA receptor subunit 2A after brain ischemia in rat hippocampus. 2005 Apr 29 3
13 15881658 Angiotensin II stimulated transcription of cyclooxygenase II is regulated by a novel kinase cascade involving Pyk2, MEKK4 and annexin II. 2005 Mar 1
14 16083718 Tumor necrosis factor-alpha mediates pancreatitis responses in acinar cells via protein kinase C and proline-rich tyrosine kinase 2. 2005 Aug 1
15 15096502 Mechanical strain on osteoblasts activates autophosphorylation of focal adhesion kinase and proline-rich tyrosine kinase 2 tyrosine sites involved in ERK activation. 2004 Jul 16 1
16 15172101 Differential regulation of FAK and PYK2 tyrosine phosphorylation after electroconvulsive shock in the rat brain. 2004 Jun 10 2
17 15236860 Lithium suppressed Tyr-402 phosphorylation of proline-rich tyrosine kinase (Pyk2) and interactions of Pyk2 and PSD-95 with NR2A in rat hippocampus following cerebral ischemia. 2004 Aug 2
18 12616494 Toll-like receptor-mediated tyrosine phosphorylation of paxillin via MyD88-dependent and -independent pathways. 2003 Mar 2
19 12620895 Cholinergic agonists transactivate EGFR and stimulate MAPK to induce goblet cell secretion. 2003 Apr 1
20 12651850 Phosphospecific site tyrosine phosphorylation of p125FAK and proline-rich kinase 2 is differentially regulated by cholecystokinin receptor type A activation in pancreatic acini. 2003 May 23 1
21 12711087 L-type voltage-gated calcium channel attends regulation of tyrosine phosphorylation of NMDA receptor subunit 2A induced by transient brain ischemia. 2003 May 16 1
22 12932810 Two types of calcium channels regulating activation of proline-rich tyrosine kinase 2 induced by transient brain ischemia in rat hippocampus. 2003 Sep 18 2
23 12950452 Inhibition of protein kinase C reduces ischemia-induced tyrosine phosphorylation of the N-methyl-d-aspartate receptor. 2003 Sep 1
24 11739373 Signal transduction of physiological concentrations of vasopressin in A7r5 vascular smooth muscle cells. A role for PYK2 and tyrosine phosphorylation of K+ channels in the stimulation of Ca2+ spiking. 2002 Mar 1 3
25 11781137 Calcium-dependent activation of Pyk2 by hypoxia. 2002 Feb 1
26 11832328 Vasopressin-mediated mitogenic signaling in intestinal epithelial cells. 2002 Mar 2
27 11997258 ANG II and LPA induce Pyk2 tyrosine phosphorylation in intestinal epithelial cells: role of Ca2+, PKC, and Rho kinase. 2002 Jun 5
28 11121380 A role for PYK2 in regulation of ERK1/2 MAP kinases and PI 3-kinase by ANG II in vascular smooth muscle. 2001 Jan 1
29 11159826 Adrenomedullin stimulates proline-rich tyrosine kinase 2 in vascular smooth muscle cells. 2001 Feb 3
30 11352632 Carbachol stimulates TYR phosphorylation and association of PKCdelta and PYK2 in pancreas. 2001 Apr 13 2
31 11352655 Electroconvulsive shock increases the phosphorylation of Pyk2 in the rat hippocampus. 2001 Apr 13 5
32 11535829 A src family tyrosine kinase inhibits neurotransmitter release from neuronal cells. 2001 Sep 11 2
33 11691539 Potassium channel blocker activates extracellular signal-regulated kinases through Pyk2 and epidermal growth factor receptor in rat cardiomyocytes. 2001 Nov 1 1
34 10790871 High-frequency synaptic stimulation induces association of fyn and c-src to distinct phosphorylated components. 2000 Apr 7 2
35 10925166 Protein kinase A activity is required for depolarization-induced proline-rich tyrosine kinase 2 and mitogen-activated protein kinase activation in PC12 cells. 2000 Aug 18 1
36 10964954 Cerebral ischemia and seizures induce tyrosine phosphorylation of PYK2 in neurons and microglial cells. 2000 Sep 1 5
37 9927621 No role for Ca++ or protein kinase C in alpha-1A adrenergic receptor activation of mitogen-activated protein kinase pathways in transfected PC12 cells. 1999 Feb 1
38 9931105 Involvement of PYK2 in angiotensin II signaling of vascular smooth muscle cells. 1999 Jan 2
39 10409647 Distinct calcium-dependent pathways of epidermal growth factor receptor transactivation and PYK2 tyrosine phosphorylation in PC12 cells. 1999 Jul 23 3
40 10531323 Cholecystokinin activates PYK2/CAKbeta by a phospholipase C-dependent mechanism and its association with the mitogen-activated protein kinase signaling pathway in pancreatic acinar cells. 1999 Oct 29 1
41 10559235 Annexin VII and annexin XI are tyrosine phosphorylated in peroxovanadate-treated dogs and in platelet-derived growth factor-treated rat vascular smooth muscle cells. 1999 Nov 19 2
42 10585878 Activation of tyrosine kinases by alpha1A-adrenergic and growth factor receptors in transfected PC12 cells. 1999 Dec 15 1
43 9422762 Cell adhesion kinase beta forms a complex with a new member, Hic-5, of proteins localized at focal adhesions. 1998 Jan 9 1
44 9430717 Regulation of a calcium-dependent tyrosine kinase in vascular smooth muscle cells by angiotensin II and platelet-derived growth factor. Dependence on calcium and the actin cytoskeleton. 1998 Jan 16 7
45 9442086 Differential regulation of Pyk2 and focal adhesion kinase (FAK). The C-terminal domain of FAK confers response to cell adhesion. 1998 Jan 23 1
46 9446569 Activation of P2Y2 receptors by UTP and ATP stimulates mitogen-activated kinase activity through a pathway that involves related adhesion focal tyrosine kinase and protein kinase C. 1998 Jan 30 1
47 9685331 ATP-stimulated activation of the mitogen-activated protein kinases through ionotrophic P2X2 purinoreceptors in PC12 cells. Difference in purinoreceptor sensitivity in two PC12 cell lines. 1998 Aug 7 1
48 9751139 Differential regulation of FAK+ and PYK2/Cakbeta, two related tyrosine kinases, in rat hippocampal slices: effects of LPA, carbachol, depolarization and hyperosmolarity. 1998 May 3
49 9776731 Calcium- and protein kinase C-dependent activation of the tyrosine kinase PYK2 by angiotensin II in vascular smooth muscle. 1998 Oct 19 2
50 9826186 Differential stimulation of proline-rich tyrosine kinase 2 and mitogen-activated protein kinase by sphingosine 1-phosphate. 1998 Oct 15 2