artemisinin

cytochrome P450 family 2 subfamily B member 6 ; Homo sapiens







18 Article(s)
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1 33599403 Allelic and genotype frequencies of major CYP2B6 polymorphisms in the Pakistani population. 2021 Mar 1
2 33875422 Pharmacogene Sequencing of a Gabonese Population with Severe Plasmodium falciparum Malaria Reveals Multiple Novel Variants with Putative Relevance for Antimalarial Treatment. 2021 Jun 17 1
3 28737446 Quantitative in vitro phenotyping and prediction of drug interaction potential of CYP2B6 substrates as victims. 2018 Jul 2
4 30159225 The Prevalence of CYP2B6 Gene Polymorphisms in Malaria-endemic Population of Timor in East Nusa Tenggara Indonesia. 2018 Aug 1
5 25760540 Effect of CAR polymorphism on the pharmacokinetics of artemisinin in healthy Chinese subjects. 2015 Feb 1
6 23467454 Pharmacogenetics of cytochrome P450 2B6 (CYP2B6): advances on polymorphisms, mechanisms, and clinical relevance. 2013 1
7 22679214 Evaluation of P450 inhibition and induction by artemisinin antimalarials in human liver microsomes and primary human hepatocytes. 2012 Sep 2
8 23506555 The evaluation of CYP2B6 inhibition by artemisinin antimalarials in recombinant enzymes and human liver microsomes. 2012 5
9 19562679 Artemisinin--a possible CYP2B6 probe substrate? 2009 Jul 5
10 19702527 Substrate specificity, regulation, and polymorphism of human cytochrome P450 2B6. 2009 Sep 1
11 18350255 A model based assessment of the CYP2B6 and CYP2C19 inductive properties by artemisinin antimalarials: implications for combination regimens. 2008 Apr 4
12 17115150 Prevalence of UGT1A9 and UGT2B7 nonsynonymous single nucleotide polymorphisms in West African, Papua New Guinean, and North American populations. 2007 Jan 1
13 16506047 Prevalence of CYP2B6 alleles in malaria-endemic populations of West Africa and Papua New Guinea. 2006 Apr 2
14 15761118 Antimalarial artemisinin drugs induce cytochrome P450 and MDR1 expression by activation of xenosensors pregnane X receptor and constitutive androstane receptor. 2005 Jun 1
15 12619052 Characterisation of the human liver in vitro metabolic pattern of artemisinin and auto-induction in the rat by use of nonlinear mixed effects modelling. 2003 Mar 1
16 12844133 Artemisinin autoinduction is caused by involvement of cytochrome P450 2B6 but not 2C9. 2003 Jul 4
17 11432537 Pharmacokinetic interactions of antimalarial agents. 2001 1
18 10583023 Identification of the human cytochrome P450 enzymes involved in the in vitro metabolism of artemisinin. 1999 Oct 12