Serine

serpin family A member 1 ; Homo sapiens







61 Article(s)
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1 34270864 Matrix metalloproteinase-13 is fully activated by neutrophil elastase and inactivates its serpin inhibitor, alpha-1 antitrypsin: Implications for osteoarthritis. 2022 Jan 1
2 34883205 Production and characterization of mono-PEGylated alpha-1 antitrypsin for augmentation therapy. 2022 Jan 25 4
3 34897938 Site-Specific Conjugation of a Selenopolypeptide to Alpha-1-antitrypsin Enhances Oxidation Resistance and Pharmacological Properties. 2022 Feb 1 2
4 35216073 Alpha 1 Antitrypsin Regulates Trophoblast Syncytialization and Inflammatory Factor Expression. 2022 Feb 10 1
5 35468329 The lipid ties of α1-antitrypsin: Structural and functional aspects. 2022 May 2
6 35508753 High-level production of wild-type and oxidation-resistant recombinant alpha-1-antitrypsin in glycoengineered CHO cells. 2022 May 4 2
7 33239231 Hypothesis: Alpha-1-antitrypsin is a promising treatment option for COVID-19. 2021 Jan 3
8 33279618 Alpha-1 antitrypsin deficiency and recombinant protein sources with focus on plant sources: Updates, challenges and perspectives. 2021 Feb 1 2
9 33284159 Alpha1-antitrypsin deficiency and asthma. 2021 Feb 1 1
10 33668611 The Autophagy Pathway: A Critical Route in the Disposal of Alpha 1-Antitrypsin Aggregates That Holds Many Mysteries. 2021 Feb 13 1
11 33721888 α1-Antitrypsin: Key Player or Bystander in Acute Respiratory Distress Syndrome? 2021 May 1 1
12 33741941 Alpha-1 antitrypsin inhibits TMPRSS2 protease activity and SARS-CoV-2 infection. 2021 Mar 19 3
13 33916165 Alpha-1 Antitrypsin-Induced Endoplasmic Reticulum Stress Promotes Invasion by Extravillous Trophoblasts. 2021 Apr 1 1
14 33969249 Alpha 1 Antitrypsin is an Inhibitor of the SARS-CoV-2-Priming Protease TMPRSS2. 2021 3
15 34084683 Heterozygous Alpha-1 Antitrypsin Deficiency Causing Pulmonary Emboli and Pulmonary Bullae. 2021 Apr 29 1
16 34192300 Placental HTRA1 cleaves α1-antitrypsin to generate a NET-inhibitory peptide. 2021 Sep 16 1
17 34246063 Alpha1-antitrypsin counteracts heme-induced endothelial cell inflammatory activation, autophagy dysfunction and death. 2021 Oct 2
18 34360796 The Course of AαVal541 as a Proteinase 3 Specific Neo-Epitope after Alpha-1-Antitrypsin Augmentation in Severe Deficient Patients. 2021 Jul 27 1
19 34502397 In Vitro and In Vivo Effects of SerpinA1 on the Modulation of Transthyretin Proteolysis. 2021 Aug 31 1
20 34640510 Correlation between α1-Antitrypsin Deficiency and SARS-CoV-2 Infection: Epidemiological Data and Pathogenetic Hypotheses. 2021 Sep 29 4
21 34677831 d-Galactose treatment increases ACE2, TMPRSS2, and FURIN and reduces SERPINA1 mRNA expression in A549 human lung epithelial cells. 2021 Oct 22 4
22 34724811 SepA Enhances Shigella Invasion of Epithelial Cells by Degrading Alpha-1 Antitrypsin and Producing a Neutrophil Chemoattractant. 2021 Dec 21 4
23 31697975 Production of α2,6-sialylated and non-fucosylated recombinant alpha-1-antitrypsin in CHO cells. 2020 Jan 10 2
24 32427833 Aggregation of M3 (E376D) variant of alpha1- antitrypsin. 2020 May 19 2
25 32503090 Anti-cytokines as a Strategy in Alpha-1 Antitrypsin Deficiency. 2020 Jul 1
26 32560429 Post-Transcriptional Regulation of Alpha One Antitrypsin by a Proteasome Inhibitor. 2020 Jun 17 1
27 32668173 Advances in Alpha-1 Antitrypsin Gene Therapy. 2020 Nov 2
28 32759494 Gene therapy for alpha 1-antitrypsin deficiency with an oxidant-resistant human alpha 1-antitrypsin. 2020 Aug 6 1
29 32960480 Ethnic differences in alpha-1 antitrypsin deficiency allele frequencies may partially explain national differences in COVID-19 fatality rates. 2020 Nov 2
30 32995386 Concerted actions by MMPs, ADAMTS and serine proteases during remodeling of the cartilage callus into bone during osseointegration of hip implants. 2020 Dec 1
31 33052338 Alpha 1 Antitrypsin is an Inhibitor of the SARS-CoV-2-Priming Protease TMPRSS2. 2020 Oct 7 4
32 33276468 Post-Translational Modifications of Circulating Alpha-1-Antitrypsin Protein. 2020 Dec 2 3
33 33311470 High-resolution ex vivo NMR spectroscopy of human Z α1-antitrypsin. 2020 Dec 11 1
34 33311976 Monocytes and Macrophages in Alpha-1 Antitrypsin Deficiency. 2020 2
35 33351103 Biomarker-guided preemption of steroid-refractory graft-versus-host disease with α-1-antitrypsin. 2020 Dec 22 2
36 31046673 Increased proteinase 3 and neutrophil elastase plasma concentrations are associated with non-alcoholic fatty liver disease (NAFLD) and type 2 diabetes. 2019 May 2 2
37 31523846 Is there any association between rs1303 (Pi*M3) variant of alpha-1 antitrypsin gene and atrial septal aneurysm development? 2019 Nov 2
38 31819391 Diagnosing Alpha-1-Antitrypsin Deficiency Using A PCR/Luminescence-Based Technology. 2019 2
39 27468101 α1 -antitrypsin Pittsburgh and plasmin-mediated proteolysis. 2016 Oct 3
40 16759229 Human mesotrypsin exhibits restricted S1' subsite specificity with a strong preference for small polar side chains. 2006 Jul 2
41 12578831 Serpin polymerization is prevented by a hydrogen bond network that is centered on his-334 and stabilized by glycerol. 2003 Apr 25 1
42 12483248 Functional analysis of recombinant pancreatic secretory trypsin inhibitor protein with amino-acid substitution. 2002 1
43 11227941 Detection and typing of human papillomavirus in anal epidermoid carcinomas: sequence variation in the E7 gene of human papillomavirus Type 16. 2001 Feb 1
44 10878477 Characterization of the new alpha-1-antitrypsin-deficient PI M-type allele, PI M(vall d'hebron) (Pro(369)-->Ser). 2000 Sep-Oct 1
45 10954248 Molecular mechanisms of alpha1-antitrypsin null alleles. 2000 Aug 2
46 10234508 Molecular characterisation of the defective alpha 1-antitrypsin alleles PI Mwurzburg (Pro369Ser), Mheerlen (Pro369Leu), and Q0lisbon (Thr68Ile). 1999 Apr 1
47 9645362 Alpha-1 antitrypsin up-regulates human B cell differentiation selectively into IgE- and IgG4- secreting cells. 1998 Jun 3
48 9852107 Human HtrA, an evolutionarily conserved serine protease identified as a differentially expressed gene product in osteoarthritic cartilage. 1998 Dec 18 1
49 9000456 Identification of novel variants of trkC mRNA transcripts in brain of African green monkeys. 1997 Jan 1
50 9316649 Prostate-specific antigen forms a complex with and cleaves alpha 1-protease inhibitor in vitro. 1997 Oct 1 1