Serine

ATR serine/threonine kinase ; Homo sapiens







95 Article(s)
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1 34627881 Adsorption of serine at the anatase TiO2/water interface: A combined ATR-FTIR and DFT study. 2022 Feb 10 3
2 35157535 Raman, Infrared and Brillouin Spectroscopies of Biofluids for Medical Diagnostics and for Detection of Biomarkers. 2022 Feb 14 1
3 35176943 Ataxia-televangelist mutated (ATM)/ ATR serine/threonine kinase (ATR)-mediated RAD51 recombinase (RAD51) promotes osteogenic differentiation and inhibits osteoclastogenesis in osteoporosis. 2022 Feb 1
4 35524559 Convergence of SIRT1 and ATR signaling to modulate replication origin dormancy. 2022 May 20 2
5 33202302 Hydrogen sulfide and DNA repair. 2021 Jan 1
6 33808326 Nuclear Translocation of SRPKs Is Associated with 5-FU and Cisplatin Sensitivity in HeLa and T24 Cells. 2021 Mar 30 1
7 34158506 The Atr-Chek1 pathway inhibits axon regeneration in response to Piezo-dependent mechanosensation. 2021 Jun 22 1
8 32117957 ATR-Mediated FANCI Phosphorylation Regulates Both Ubiquitination and Deubiquitination of FANCD2. 2020 1
9 32863904 Digitoxin inhibits proliferation of multidrug-resistant HepG2 cells through G2/M cell cycle arrest and apoptosis. 2020 Oct 4
10 32966758 PCAF-Mediated Histone Acetylation Promotes Replication Fork Degradation by MRE11 and EXO1 in BRCA-Deficient Cells. 2020 Oct 15 2
11 32984322 PP2A Regulates Phosphorylation-Dependent Isomerization of Cytoplasmic and Mitochondrial-Associated ATR by Pin1 in DNA Damage Responses. 2020 2
12 30470507 The Ataxia telangiectasia-mutated and Rad3-related protein kinase regulates cellular hydrogen sulfide concentrations. 2019 Jan 4
13 30987998 Inhibition of Ataxia-Telangiectasia Mutated and RAD3-Related (ATR) Overcomes Oxaliplatin Resistance and Promotes Antitumor Immunity in Colorectal Cancer. 2019 Jun 1 1
14 31296660 Temporal and differential regulation of KAISO-controlled transcription by phosphorylated and acetylated p53 highlights a crucial regulatory role of apoptosis. 2019 Aug 30 4
15 29244158 ZNF830 mediates cancer chemoresistance through promoting homologous-recombination repair. 2018 Feb 16 1
16 29695073 Design, Synthesis, and Docking Studies of New Torin2 Analogs as Potential ATR/mTOR Kinase Inhibitors. 2018 Apr 24 1
17 30237857 Trisenox disrupts MDM2-DAXX-HAUSP complex and activates p53, cell cycle regulation and apoptosis in acute leukemia cells. 2018 Sep 4 4
18 30327428 Sirtuin 1-mediated deacetylation of XPA DNA repair protein enhances its interaction with ATR protein and promotes cAMP-induced DNA repair of UV damage. 2018 Dec 7 3
19 30380295 Evaluation of Maltose Binding Protein-Tagged hATR Kinase Domain Catalytic Activity with p53 Ser-15 Phosphorylation. 2018 Nov 27 2
20 28264028 Parvovirus B19 NS1 protein induces cell cycle arrest at G2-phase by activating the ATR-CDC25C-CDK1 pathway. 2017 Mar 1
21 28986587 The drinking water contaminant dibromoacetonitrile delays G1-S transition and suppresses Chk1 activation at broken replication forks. 2017 Oct 6 1
22 29114052 DNA damage response protein TOPBP1 regulates X chromosome silencing in the mammalian germ line. 2017 Nov 21 1
23 29163782 BMI1 reduces ATR activation and signalling caused by hydroxyurea. 2017 Oct 27 2
24 26620371 A crucial role for ATR in the regulation of deoxycytidine kinase activity. 2016 Jan 15 1
25 26695548 Replication stress induced site-specific phosphorylation targets WRN to the ubiquitin-proteasome pathway. 2016 Jan 5 1
26 25468710 Untangling the ATR-CHEK1 network for prognostication, prediction and therapeutic target validation in breast cancer. 2015 Mar 1
27 25659338 Mec1-dependent phosphorylation of Mms21 modulates its SUMO ligase activity. 2015 Apr 1
28 26019182 Caffeine impairs resection during DNA break repair by reducing the levels of nucleases Sae2 and Dna2. 2015 Aug 18 1
29 26039276 KA1-targeted regulatory domain mutations activate Chk1 in the absence of DNA damage. 2015 Jun 3 2
30 26320175 Mutation of the BRCA1 SQ-cluster results in aberrant mitosis, reduced homologous recombination, and a compensatory increase in non-homologous end joining. 2015 Sep 29 1
31 26438152 Functional analyses of ATM, ATR and Fanconi anemia proteins in lung carcinoma : ATM, ATR and FA in lung carcinoma. 2015 Oct 5 2
32 23178497 Coordinated regulation of XPA stability by ATR and HERC2 during nucleotide excision repair. 2014 Jan 2 1
33 24901225 Mutation of serine 1333 in the ATR HEAT repeats creates a hyperactive kinase. 2014 1
34 25301947 Phosphorylation of the BRCA1 C terminus (BRCT) repeat inhibitor of hTERT (BRIT1) protein coordinates TopBP1 protein recruitment and amplifies ataxia telangiectasia-mutated and Rad3-related (ATR) Signaling. 2014 Dec 5 1
35 23438602 ATM- and ATR-mediated phosphorylation of XRCC3 regulates DNA double-strand break-induced checkpoint activation and repair. 2013 May 1
36 23698467 ATR-dependent phosphorylation of FANCM at serine 1045 is essential for FANCM functions. 2013 Jul 15 2
37 22223653 Induction of DNA damage signaling upon Rift Valley fever virus infection results in cell cycle arrest and increased viral replication. 2012 Mar 2 1
38 22357623 P90 RSK arranges Chk1 in the nucleus for monitoring of genomic integrity during cell proliferation. 2012 Apr 3
39 22496453 Roles of Kruppel-associated Box (KRAB)-associated Co-repressor KAP1 Ser-473 Phosphorylation in DNA Damage Response. 2012 Jun 1 2
40 22855742 Autoregulatory mechanisms of phosphorylation of checkpoint kinase 1. 2012 Aug 1 3
41 21857991 ATR-p53 restricts homologous recombination in response to replicative stress but does not limit DNA interstrand crosslink repair in lung cancer cells. 2011 1
42 21864706 BRCA1 is required for hMLH1 stabilization following doxorubicin-induced DNA damage. 2011 Dec 3
43 20622265 SOCS1, a novel interaction partner of p53 controlling oncogene-induced senescence. 2010 Jul 1
44 20818375 Phosphorylation of MLL by ATR is required for execution of mammalian S-phase checkpoint. 2010 Sep 16 1
45 21533002 Tandem BRCT Domains: DNA's Praetorian Guard. 2010 Nov 1
46 21779472 The "Mutated in Colorectal Cancer" Protein Is a Novel Target of the UV-Induced DNA Damage Checkpoint. 2010 Sep 1
47 19049966 ATR and H2AX cooperate in maintaining genome stability under replication stress. 2009 Feb 27 1
48 19109555 ATR-dependent phosphorylation of FANCA on serine 1449 after DNA damage is important for FA pathway function. 2009 Mar 5 4
49 19154794 ATR (AT mutated Rad3 related) activity stabilizes Cdc6 and delays G2/M-phase entry during hydroxyurea-induced S-phase arrest of HeLa cells. 2009 Jun 3
50 19477925 Estrogen inhibits ATR signaling to cell cycle checkpoints and DNA repair. 2009 Jul 1