Simvastatin

C-X-C motif chemokine ligand 8 ; Homo sapiens







33 Article(s)
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1 29232287 The Effects of Known Cardioprotective Drugs on Proinflammatory Cytokine Secretion From Human Coronary Artery Endothelial Cells. 2019 May/Jun 1
2 30312114 Repurposing simvastatin as a therapy for preterm labor: evidence from preclinical models. 2019 Feb 1
3 29865262 Differential Effects of Statins on Inflammatory Interleukin-8 and Antimicrobial Peptide Human Β-Defensin 2 Responses in Salmonella-Infected Intestinal Epithelial Cells. 2018 Jun 2 1
4 30100024 Simvastatin reduces the TLR4-induced inflammatory response in human aortic valve interstitial cells. 2018 Oct 1
5 28601733 Effect of 1.2% of simvastatin gel as a local drug delivery system on Gingival Crevicular Fluid interleukin-6 & interleukin-8 levels in non surgical treatment of chronic periodontitis patients. 2017 Oct 3
6 28713941 Additive antitumor effects of celecoxib and simvastatin on head and neck squamous cell carcinoma in vitro. 2017 Sep 1
7 29250545 Efficacy and Mechanism of Preoperative Simvastatin Therapy on Myocardial Protection after Extracorporeal Circulation. 2017 1
8 29285177 Anti-inflammatory effects of Simvastatin in patients with acute intracerebral hemorrhage in an intensive care unit. 2017 Dec 1
9 27086089 Perioperative Simvastatin Therapy in Major Colorectal Surgery: A Prospective, Double-Blind Randomized Controlled Trial. 2016 Aug 2
10 27195204 Effect of topical simvastatin (1.2 mg) on gingival crevicular fluid interleukin-6, interleukin-8 and interleukin-10 levels in chronic periodontitis - A clinicobiochemical study. 2016 May-Aug 2
11 27411707 Simvastatin Treatment Modulates Mechanically-Induced Injury and Inflammation in Respiratory Epithelial Cells. 2016 Dec 1
12 24629144 Simvastatin down-regulates the production of interleukin-8 by neutrophil leukocytes from dyslipidemic patients. 2014 Mar 15 4
13 25432084 Effects of simvastatin on cell viability and proinflammatory pathways in lung adenocarcinoma cells exposed to hydrogen peroxide. 2014 Nov 29 2
14 22915623 Simvastatin inhibits the pro-inflammatory and pro-thrombotic effects of IL-17 and TNF-α on endothelial cells. 2013 May 1
15 22796581 Simvastatin reduces myocardial injury undergoing noncoronary artery cardiac surgery: a randomized controlled trial. 2012 Sep 1
16 20607595 Effects of simvastatin on proinflammatory cytokines and matrix metalloproteinases in hypercholesterolemic individuals. 2011 Aug 1
17 20870757 A randomized clinical trial of hydroxymethylglutaryl- coenzyme a reductase inhibition for acute lung injury (The HARP Study). 2011 Mar 1 1
18 21173096 Participation of Mac-1, LFA-1 and VLA-4 integrins in the in vitro adhesion of sickle cell disease neutrophils to endothelial layers, and reversal of adhesion by simvastatin. 2011 Apr 2
19 20065508 IL-6 and IL-8 responses of colorectal cancer in vivo and in vitro cancer cells subjected to simvastatin. 2009 Dec 5
20 18037374 Simvastatin enhances endothelial differentiation of peripheral blood mononuclear cells in hypercholesterolemic patients and induces pro-angiogenic cytokine IL-8 secretion from monocytes. 2008 Feb 3
21 18203325 High concentration simvastatin induces apoptosis in fibroblast-like synoviocytes from patients with rheumatoid arthritis. 2008 Feb 2
22 16942919 Simvastatin stimulates macrophage interleukin-1beta secretion through an isoprenylation-dependent mechanism. 2007 Feb 1
23 17383342 Simvastatin increases neutrophil apoptosis and reduces inflammatory reaction after coronary surgery. 2007 Apr 1
24 17466485 Simvastatin and fluvastatin reduce interleukin-6 and interleukin-8 lipopolysaccharide (LPS) stimulated production by isolated human monocytes from chronic kidney disease patients. 2007 Jul 1
25 17519305 Concomitant reduction of low-density lipoprotein-cholesterol and biomarkers of inflammation with low-dose simvastatin therapy in patients with type 1 diabetes. 2007 Aug 1
26 17888208 Influence of simvastatin on the production of pro-inflammatory cytokines and nitric oxide by activated human chondrocytes. 2007 Jul-Aug 3
27 18078616 Simvastatin inhibits cytokine production and nuclear factor-kB activation in interleukin 1beta-stimulated synoviocytes from rheumatoid arthritis patients. 2007 Sep-Oct 3
28 18260853 [Clinico-diagnostic significance of cytokine activation and changes of morphofunctional parameters of the heart in patients with chronic heart failure and possibilities of correction of revealed disturbances with simvastatin]. 2007 1
29 16249194 In vivo and in vitro effects of simvastatin on inflammatory markers in pre-dialysis patients. 2006 Feb 1
30 16511915 Simvastatin inhibits production of interleukin 6 (IL-6) and IL-8 and cell proliferation induced by tumor necrosis factor-alpha in fibroblast-like synoviocytes from patients with rheumatoid arthritis. 2006 Mar 6
31 16723648 Simvastatin decreases IL-6 and IL-8 production in epithelial cells. 2006 Jun 2
32 17082725 Simvastatin treatment modifies polymorphonuclear leukocyte function in high-risk individuals: a longitudinal study. 2006 Dec 1
33 12117737 Simvastatin reduces expression of cytokines interleukin-6, interleukin-8, and monocyte chemoattractant protein-1 in circulating monocytes from hypercholesterolemic patients. 2002 Jul 1 3