2-(2-amino-3-methoxyphenyl)-4H-1-benzopyran-4-one

C-X-C motif chemokine ligand 8 ; Homo sapiens







85 Article(s)
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1 30851105 EGFR-Dependent IL8 Production by Airway Epithelial Cells After Exposure to the Food Flavoring Chemical 2,3-Butanedione. 2019 Jun 1 1
2 30466991 Berberine down-regulates IL-8 expression through inhibition of the EGFR/MEK/ERK pathway in triple-negative breast cancer cells. 2018 Nov 15 1
3 26431069 Induction of proinflammatory cytokine production in intervertebral disc cells by macrophage-like THP-1 cells requires mitogen-activated protein kinase activity. 2016 Jan 1
4 26483408 Activation of the Classical Mitogen-Activated Protein Kinases Is Part of the Shiga Toxin-Induced Ribotoxic Stress Response and May Contribute to Shiga Toxin-Induced Inflammation. 2016 Jan 1
5 26848751 The Effect of (-)-Epigallocatechin-3-Gallate on IL-1β Induced IL-8 Expression in Orbital Fibroblast from Patients with Thyroid-Associated Ophthalmopathy. 2016 1
6 24106166 Pb²⁺ induced IL-8 gene expression by extracellular signal-regulated kinases and the transcription factor, activator protein 1, in human gastric carcinoma cells. 2015 Mar 1
7 24854880 Lipopolysaccharide-regulated production of bone sialoprotein and interleukin-8 in human periodontal ligament fibroblasts: the role of toll-like receptors 2 and 4 and the MAPK pathway. 2015 Apr 1
8 24126532 Hemoglobin receptor protein from Porphyromonas gingivalis induces interleukin-8 production in human gingival epithelial cells through stimulation of the mitogen-activated protein kinase and NF-κB signal transduction pathways. 2014 Jan 1
9 24277696 Thrombin-induced CCAAT/enhancer-binding protein β activation and IL-8/CXCL8 expression via MEKK1, ERK, and p90 ribosomal S6 kinase 1 in lung epithelial cells. 2014 Jan 1 4
10 24479526 IL-33 stimulates CXCL8/IL-8 secretion in goblet cells but not normally differentiated airway cells. 2014 Apr 2
11 23357535 Thrombin-induced NF-κB activation and IL-8/CXCL8 release is mediated by c-Src-dependent Shc, Raf-1, and ERK pathways in lung epithelial cells. 2013 May 1
12 23779254 Modulation of IL-8 boosted by Mycoplasma pneumoniae lysate in human airway epithelial cells. 2013 Aug 1
13 23924923 Hepatocyte growth factor-mediated gastrin-releasing peptide induces IL-8 expression through Ets-1 in gastric cancer cells. 2013 1
14 21545687 Regulatory mechanisms of interleukin-8 production induced by tumour necrosis factor-α in human hepatocellular carcinoma cells. 2012 Mar 1
15 21932059 ICAM-1 and IL-8 are expressed by DEHP and suppressed by curcumin through ERK and p38 MAPK in human umbilical vein endothelial cells. 2012 Jun 1
16 22721959 Clostridium perfringens alpha-toxin induces the release of IL-8 through a dual pathway via TrkA in A549 cells. 2012 Oct 2
17 20739465 TRPV1 activation is required for hypertonicity-stimulated inflammatory cytokine release in human corneal epithelial cells. 2011 Jan 1
18 21172926 Advanced glycation end products induce the expression of interleukin-6 and interleukin-8 by receptor for advanced glycation end product-mediated activation of mitogen-activated protein kinases and nuclear factor-κB in human osteoarthritis chondrocytes. 2011 May 1
19 21631990 IL-8 reduces VCAM-1 secretion of smooth muscle cells by increasing p-ERK expression when 3-D co-cultured with vascular endothelial cells. 2011 Jun 1 1
20 21637924 Tetramethylpyrazine inhibits migration of SKOV3 human ovarian carcinoma cells and decreases the expression of interleukin-8 via the ERK1/2, p38 and AP-1 signaling pathways. 2011 Sep 1
21 21796149 High calcium, ATP, and poly(I:C) augment the immune response to β-glucan in normal human epidermal keratinocytes. 2011 Nov 1
22 19898747 Enteroaggregative Escherichia coli infection induces IL-8 production via activation of mitogen-activated protein kinases and the transcription factors NF-kappaB and AP-1 in INT-407 cells. 2010 Apr 1
23 20304034 Galactose specific adhesin of enteroaggregative E. coli induces IL-8 secretion via activation of MAPK and STAT-3 in INT-407 cells. 2010 Jun 1
24 20412422 Oxidized low-density lipoprotein increases interleukin-8 production in human gingival epithelial cell line Ca9-22. 2010 Aug 1
25 19029040 Extracellular nucleotides and interleukin-8 production by ARPE cells: potential role of danger signals in blood-retinal barrier activation. 2009 Mar 1
26 19373630 Asthma drugs counter-regulate interleukin-8 release stimulated by sodium sulfite in an A549 cell line. 2009 Apr 1
27 19507016 Tec kinase mediating IL-8 transcription in monocytes stimulated with LPS. 2009 Aug 1
28 19526316 Hepatocyte growth factor induced up-regulations of VEGF through Egr-1 in hepatocellular carcinoma cells. 2009 1
29 19558546 Bovine glycomacropeptide induces cytokine production in human monocytes through the stimulation of the MAPK and the NF-kappaB signal transduction pathways. 2009 Aug 2
30 19567187 [Effects of erythromycin on the synthesis of interleukin-8 and gamma-glutamylcysteine synthetase induced by 4-hydroxynonenal in the bronchial epithelial cells]. 2009 Feb 1
31 19709445 Inhibitory effect of IL-8 on insulin action in human adipocytes via MAP kinase pathway. 2009 Aug 27 2
32 17996917 Fluoride-induced IL-8 release in human epithelial lung cells: relationship to EGF-receptor-, SRC- and MAP-kinase activation. 2008 Feb 15 1
33 18390828 MMP-12 induces IL-8/CXCL8 secretion through EGFR and ERK1/2 activation in epithelial cells. 2008 Jun 2
34 18565136 Irsogladine maleate abolishes the increase in interleukin-8 levels caused by outer membrane protein 29 from Aggregatibacter (Actinobacillus) actinomycetemcomitans through the ERK pathway in human gingival epithelial cells. 2008 Oct 1
35 18639962 Activation of MAPK participates in low shear stress-induced IL-8 gene expression in endothelial cells. 2008 1
36 18662754 Oxidative stress and apoptosis induced by titanium dioxide nanoparticles in cultured BEAS-2B cells. 2008 Aug 28 2
37 18789871 Insulin induces monocytic CXCL8 secretion by the mitogenic signalling pathway. 2008 Oct 1
38 18953964 [The mechanism of inhibition by ginkgolide B on interleukin-8 production induced by 4-hydroxynonenal in bronchial epithelial cells]. 2008 May 2
39 18974961 Induction of IL-8 in periodontal ligament cells by H(2)O (2). 2008 Oct 1
40 17178391 Highly homologous Mycobacterium tuberculosis chaperonin 60 proteins with differential CD14 dependencies stimulate cytokine production by human monocytes through cooperative activation of p38 and ERK1/2 mitogen-activated protein kinases. 2007 Feb 1
41 17460254 Mitomycin C upregulates IL-8 and MCP-1 chemokine expression via mitogen-activated protein kinases in corneal fibroblasts. 2007 May 1
42 17876544 Inflammatory responses induced by interleukin-17 family members in human colonic subepithelial myofibroblasts. 2007 Sep 1
43 16085674 Macrolide antibiotics modulate ERK phosphorylation and IL-8 and GM-CSF production by human bronchial epithelial cells. 2006 Jan 1
44 16197369 Transcriptional regulation of lysophosphatidic acid-induced interleukin-8 expression and secretion by p38 MAPK and JNK in human bronchial epithelial cells. 2006 Feb 1 1
45 16202406 JNK and ERK MAP kinases mediate induction of IL-1beta, TNF-alpha and IL-8 following hyperosmolar stress in human limbal epithelial cells. 2006 Apr 1
46 16491014 Histamine H1 receptor-stimulated interleukin 8 and granulocyte macrophage colony-stimulating factor production by bronchial epithelial cells requires extracellular signal-regulated kinase signaling via protein kinase C. 2006 1
47 16634798 Circulating IgA from acute stage of childhood Henoch-Schönlein purpura can enhance endothelial interleukin (IL)-8 production through MEK/ERK signalling pathway. 2006 May 1
48 16697690 Induction of interleukin-8 secretion and activation of ERK1/2, p38 MAPK signaling pathways by thrombin in dermal fibroblasts. 2006 2
49 16761312 Signaling events involved in cytokine and chemokine production induced by secretory phospholipase A2 in human lung macrophages. 2006 Jul 1
50 15585560 Mechanical stretch stimulates interleukin-8 production in endometrial stromal cells: possible implications in endometrium-related events. 2005 Feb 1