ruboxistaurin

protein kinase C beta ; Homo sapiens







39 Article(s)
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1 31785237 PKCβII specifically regulates KCNQ1/KCNE1 channel membrane localization. 2020 Jan 1
2 28128334 Protein Kinase C β: a New Target Therapy to Prevent the Long-Term Atypical Antipsychotic-Induced Weight Gain. 2017 Jun 1
3 26501476 The Protein Kinase C Inhibitor: Ruboxistaurin. 2016 1
4 25815500 [Roles of PKCβ/P66Shc oxidative stress signal pathway in mediating hyperoxia-induced ROS production in alveolar epithelial cells]. 2015 Mar 4
5 24722289 Selective inhibition of protein kinase C β2 attenuates the adaptor P66 Shc-mediated intestinal ischemia-reperfusion injury. 2014 Apr 10 1
6 24008236 Endothelial nitric oxide synthase phosphorylation at Threonine 495 and mitochondrial reactive oxygen species formation in response to a high H₂O₂ concentration. 2013 1
7 24497733 Computational investigation of pkcβ inhibitors for the treatment of diabetic retinopathy. 2013 2
8 20939796 Protein kinase C inhibitors in the treatment of diabetic retinopathy. Review. 2011 Mar 1 2
9 22204135 A PKC-beta inhibitor prompts the HUVECs apoptosis-induced by advanced glycation end products. 2011 Nov 2
10 20875828 Blockade of PKC-beta protects HUVEC from advanced glycation end products induced inflammation. 2010 Dec 1
11 18949545 Selective PKC beta inhibition with ruboxistaurin and endothelial function in type-2 diabetes mellitus. 2009 Feb 2
12 18989348 Sustained moderate visual loss as a predictive end point for visual loss in non-proliferative diabetic retinopathy. 2009 Jan 1
13 19929710 Ruboxistaurin: PKC-beta inhibition for complications of diabetes. 2009 Dec 3
14 18214957 Protein kinase C isozymes and their selectivity towards ruboxistaurin. 2008 Jul 1
15 17472415 Ruboxistaurin: LY 333531. 2007 1
16 17504923 Role of protein kinase Cbeta in rhythmic contractions of human pregnant myometrium. 2007 Apr 2
17 17720889 New pharmacologic approaches to treating diabetic retinopathy. 2007 Sep 1 1
18 18054736 PKC inhibition and diabetic microvascular complications. 2007 Dec 1
19 19885168 The beta-specific protein kinase C inhibitor ruboxistaurin (LY333531) suppresses glucose-induced adhesion of human monocytes to endothelial cells in vitro. 2007 Nov 1
20 16384948 Inhibition of PKC beta by oral administration of ruboxistaurin is well tolerated and ameliorates diabetes-induced retinal hemodynamic abnormalities in patients. 2006 Jan 3
21 16564096 Selective role of PKCbeta enzymatic function in regulating cell survival mediated by B cell antigen receptor cross-linking. 2006 May 15 1
22 16626305 Homocysteine stimulates phosphorylation of NADPH oxidase p47phox and p67phox subunits in monocytes via protein kinase Cbeta activation. 2006 Aug 15 1
23 16896067 Disposition of [14C]ruboxistaurin in humans. 2006 Nov 2
24 16989901 Effect of ruboxistaurin on visual loss in patients with diabetic retinopathy. 2006 Dec 1
25 17044810 Clinical safety of the selective PKC-beta inhibitor, ruboxistaurin. 2006 Nov 3
26 17084284 Protein kinase C beta/early growth response-1 pathway: a key player in ischemia, atherosclerosis, and restenosis. 2006 Nov 7 3
27 17160912 Protein kinase C beta inhibition: A novel therapeutic strategy for diabetic microangiopathy. 2006 Dec 1
28 15822057 The next generation of diabetic nephropathy therapies: an update. 2005 Apr 2
29 16160002 Ruboxistaurin, a protein kinase C beta inhibitor, as an emerging treatment for diabetes microvascular complications. 2005 Oct 3
30 12789620 Ruboxistaurin (Eli Lilly). 2003 Feb 1
31 14581181 Possible role of the protein kinase C/CPI-17 pathway in the augmented contraction of human myometrium after gestation. 2003 Dec 1
32 14683472 Selective protein kinase C inhibitors and their applications. 2003 Dec 1
33 12507628 The potential role of PKC beta in diabetic retinopathy and macular edema. 2002 Dec 1
34 11178962 Role of PKC and TGF-beta receptor in glucose-induced proliferation of smooth muscle cells. 2001 Feb 16 1
35 11440359 Protein kinase C activation: isozyme-specific effects on metabolism and cardiovascular complications in diabetes. 2001 Jun 3
36 11903393 Protein kinase C and the development of diabetic vascular complications. 2001 Dec 1
37 10452527 PKC-beta and PKC-zeta mediate opposing effects on proximal tubule Na+,K+-ATPase activity. 1999 Jul 30 1
38 10485491 Protein kinase C lies on the signaling pathway for vascular endothelial growth factor-mediated tumor development and angiogenesis. 1999 Sep 1 1
39 8709095 (S)-13-[(dimethylamino)methyl]-10,11,14,15-tetrahydro-4,9:16, 21-dimetheno-1H, 13H-dibenzo[e,k]pyrrolo[3,4-h][1,4,13]oxadiazacyclohexadecene-1,3(2H)-d ione (LY333531) and related analogues: isozyme selective inhibitors of protein kinase C beta. 1996 Jul 5 1