Fatty Acids

stearoyl-Coenzyme A desaturase 1 ; Mus musculus







90 Article(s)
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1 35158113 Dysregulated lipid metabolism blunts the sensitivity of cancer cells to EZH2 inhibitor. 2022 Mar 1
2 35443751 Stearoyl-CoA Desaturase inhibition reverses immune, synaptic and cognitive impairments in an Alzheimer's disease mouse model. 2022 Apr 20 3
3 35624087 PI(18:1/18:1) is a SCD1-derived lipokine that limits stress signaling. 2022 May 27 1
4 33538705 Effects of ChREBP deficiency on adrenal lipogenesis and steroidogenesis. 2021 Mar 1
5 33565799 Inhibition of Stearoyl-CoA Desaturase Induces the Unfolded Protein Response in Pancreatic Tumors and Suppresses Their Growth. 2021 Feb 1 2
6 34151243 Aramchol downregulates stearoyl CoA-desaturase 1 in hepatic stellate cells to attenuate cellular fibrogenesis. 2021 Jun 2
7 34486791 Increased lipogenesis is critical for self-renewal and growth of breast cancer stem cells: Impact of omega-3 fatty acids. 2021 Dec 1
8 34972124 Single-cell chromatin accessibility and lipid profiling reveals SCD1-dependent metabolic shift in adipocytes induced by bariatric surgery. 2021 1
9 31241768 SCD1 regulates the AMPK/SIRT1 pathway and histone acetylation through changes in adenine nucleotide metabolism in skeletal muscle. 2020 Feb 2
10 31676951 Saturated and monounsaturated fatty acids in membranes are determined by the gene expression of their metabolizing enzymes SCD1 and ELOVL6 regulated by the intake of dietary fat. 2020 Sep 1
11 31952262 Beneficial Effects of SREBP Decoy Oligodeoxynucleotide in an Animal Model of Hyperlipidemia. 2020 Jan 15 1
12 32103057 Spatial modeling of prostate cancer metabolic gene expression reveals extensive heterogeneity and selective vulnerabilities. 2020 Feb 26 2
13 32408172 GPAT4-Generated Saturated LPAs Induce Lipotoxicity through Inhibition of Autophagy by Abnormal Formation of Omegasomes. 2020 May 22 4
14 32566176 Lycium ruthenicum Murr. alleviates nonalcoholic fatty liver in mice. 2020 Jun 1
15 30504007 Diallyl disulfide potentiates anti-obesity effect of green tea in high-fat/high-sucrose diet-induced obesity. 2019 Feb 1
16 30721698 Penta-O-galloyl-β-d-glucose, a hydrolysable tannin from Radix Paeoniae Alba, inhibits adipogenesis and TNF-α-mediated inflammation in 3T3-L1 cells. 2019 Apr 1 1
17 30735856 Hepatic stellate cell activation: A source for bioactive lipids. 2019 May 1
18 30930246 Stearoyl CoA Desaturase Is Essential for Regulation of Endoplasmic Reticulum Homeostasis and Tumor Growth in Glioblastoma Cancer Stem Cells. 2019 Apr 9 1
19 31673045 Hepatic Stearoyl-CoA desaturase-1 deficiency-mediated activation of mTORC1- PGC-1α axis regulates ER stress during high-carbohydrate feeding. 2019 Oct 31 5
20 31690632 Hepatic stearoyl CoA desaturase 1 deficiency increases glucose uptake in adipose tissue partially through the PGC-1α-FGF21 axis in mice. 2019 Dec 20 2
21 29149647 Dietary fish oil differentially ameliorates high-fructose diet-induced hepatic steatosis and hyperlipidemia in mice depending on time of feeding. 2018 Feb 1
22 29175182 Impact of diesel exhaust exposure on the liver of mice fed on omega-3 polyunsaturated fatty acids-deficient diet. 2018 Jan 2
23 29326439 Lung fibroblasts promote metastatic colonization through upregulation of stearoyl-CoA desaturase 1 in tumor cells. 2018 Mar 1
24 29401633 Hydroxysteroid (17β) dehydrogenase 13 deficiency triggers hepatic steatosis and inflammation in mice. 2018 Jun 1
25 29463801 Compensatory increases in tear volume and mucin levels associated with meibomian gland dysfunction caused by stearoyl-CoA desaturase-1 deficiency. 2018 Feb 20 1
26 29572893 Subchronic cadmium exposure upregulates the mRNA level of genes associated to hepatic lipid metabolism in adult female CD1 mice. 2018 Jul 1
27 29595454 [Knockdown of dopamine receptor D2 upregulates the expression of adiogenic genes in mouse primary mesencephalic neurons]. 2018 Jan 1
28 30063922 Deletion of Stearoyl-CoA Desaturase-1 From the Intestinal Epithelium Promotes Inflammation and Tumorigenesis, Reversed by Dietary Oleate. 2018 Nov 1
29 28542499 Lipidomic and metabolic changes in the P4-type ATPase ATP10D deficient C57BL/6J wild type mice upon rescue of ATP10D function. 2017 2
30 28659287 Reduced SCD1 activity alters markers of fatty acid reesterification, glyceroneogenesis, and lipolysis in murine white adipose tissue and 3T3-L1 adipocytes. 2017 Sep 1 2
31 28803985 miR-199a-3p affects adipocytes differentiation and fatty acid composition through targeting SCD. 2017 Oct 7 1
32 29159325 Role of Aramchol in steatohepatitis and fibrosis in mice. 2017 Nov 2
33 27021137 A lipidomics investigation into the intervention of celastrol in experimental colitis. 2016 Apr 26 3
34 27188441 BTG1 ameliorates liver steatosis by decreasing stearoyl-CoA desaturase 1 (SCD1) abundance and altering hepatic lipid metabolism. 2016 May 17 2
35 27609767 Deficiency of stearoyl-CoA desaturase-1 aggravates colitogenic potential of adoptively transferred effector T cells. 2016 Oct 1 3
36 27627966 Tlr4-mutant mice are resistant to acute alcohol-induced sterol-regulatory element binding protein activation and hepatic lipid accumulation. 2016 Sep 15 1
37 27806127 Rifampicin-Induced Hepatic Lipid Accumulation: Association with Up-Regulation of Peroxisome Proliferator-Activated Receptor γ in Mouse Liver. 2016 1
38 27834856 Stearoyl-CoA Desaturase-1 Protects Cells against Lipotoxicity-Mediated Apoptosis in Proximal Tubular Cells. 2016 Nov 9 2
39 25959085 SCD1 inhibition during 3T3-L1 adipocyte differentiation remodels triacylglycerol, diacylglycerol and phospholipid fatty acid composition. 2015 Jul 2
40 26679101 Adipose tissue fatty acid chain length and mono-unsaturation increases with obesity and insulin resistance. 2015 Dec 17 1
41 24296537 Critical role of SCD1 in autophagy regulation via lipogenesis and lipid rafts-coupled AKT-FOXO1 signaling pathway. 2014 Feb 4
42 24306959 Effect of high versus low doses of fat and vitamin A dietary supplementation on fatty acid composition of phospholipids in mice. 2014 Jan 3
43 24566853 Inhibition of stearoyl-CoA desaturase-1 in differentiating 3T3-L1 preadipocytes upregulates elongase 6 and downregulates genes affecting triacylglycerol synthesis. 2014 Nov 2
44 25147951 Cartilage-specific ablation of site-1 protease in mice results in the endoplasmic reticulum entrapment of type IIb procollagen and down-regulation of cholesterol and lipid homeostasis. 2014 1
45 25310357 Ezetimibe prevents the development of non‑alcoholic fatty liver disease induced by high‑fat diet in C57BL/6J mice. 2014 Dec 1
46 22732909 An indoline-derived compound that markedly reduces mouse body weight. 2013 May 1
47 23355796 Fatty acid and transcriptome profiling of longissimus dorsi muscles between pig breeds differing in meat quality. 2013 3
48 23516000 Down-regulation of hepatic stearoyl-CoA desaturase-1 expression by fucoxanthin via leptin signaling in diabetic/obese KK-A(y) mice. 2013 May 2
49 23785402 Systemic down-regulation of delta-9 desaturase promotes muscle oxidative metabolism and accelerates muscle function recovery following nerve injury. 2013 1
50 23918045 SCD1 activity in muscle increases triglyceride PUFA content, exercise capacity, and PPARδ expression in mice. 2013 Oct 2