Tretinoin

cytochrome P450, family 26, subfamily a, polypeptide 1 ; Mus musculus







70 Article(s)
Download
PMID
Title
Pub. Year
#Total Relationships
1 35063128 Multi-layered regulation of neuroectoderm differentiation by retinoic acid in a primitive streak-like context. 2022 Feb 8 1
2 33441739 Low retinoic acid levels mediate regionalization of the Sertoli valve in the terminal segment of mouse seminiferous tubules. 2021 Jan 13 2
3 31676951 Saturated and monounsaturated fatty acids in membranes are determined by the gene expression of their metabolizing enzymes SCD1 and ELOVL6 regulated by the intake of dietary fat. 2020 Sep 1
4 32027669 Cyp1b1 directs Srebp-mediated cholesterol and retinoid synthesis in perinatal liver; Association with retinoic acid activity during fetal development. 2020 2
5 33105029 Knockout of Cyp26a1 and Cyp26b1 during postnatal life causes reduced lifespan, dermatitis, splenomegaly, and systemic inflammation in mice. 2020 Dec 2
6 30555939 Elongation of Müllerian ducts and connection to urogenital sinus determine the borderline of uterine and vaginal development. 2019 Mar 2
7 30916783 Delayed onset of smooth muscle cell differentiation leads to hydroureter formation in mice with conditional loss of the zinc finger transcription factor gene Gata2 in the ureteric mesenchyme. 2019 Aug 2
8 31167781 The retinoic acid hydroxylase Cyp26a1 has minor effects on postnatal vitamin A homeostasis, but is required for exogenous atRA clearance. 2019 Jul 19 4
9 31561560 Divergent Roles of CYP26B1 and Endogenous Retinoic Acid in Mouse Fetal Gonads. 2019 Sep 26 1
10 29781215 Serine Threonine Kinase Receptor-Associated Protein Deficiency Impairs Mouse Embryonic Stem Cells Lineage Commitment Through CYP26A1-Mediated Retinoic Acid Homeostasis. 2018 Sep 3
11 29928370 Retinoic acid-metabolizing enzyme cytochrome P450 26A1 promotes skin carcinogenesis induced by 7,12-dimethylbenz[a]anthracene. 2018 Jun 3
12 28087565 Perturbation of Retinoid Homeostasis Increases Malformation Risk in Embryos Exposed to Pregestational Diabetes. 2017 Apr 2
13 28422378 Cellular retinoic acid bioavailability in various pathologies and its therapeutic implication. 2017 Jun 4
14 28446509 Inhibition of the all-trans Retinoic Acid (atRA) Hydroxylases CYP26A1 and CYP26B1 Results in Dynamic, Tissue-Specific Changes in Endogenous atRA Signaling. 2017 Jul 5
15 27638841 Restoring Retinoic Acid Attenuates Intestinal Inflammation and Tumorigenesis in APCMin/+ Mice. 2016 Nov 2
16 24325348 Regulation of cyp26a1 on Th17 cells in mouse peri-implantation. 2014 Mar 1
17 25305491 Cyp26b1 within the growth plate regulates bone growth in juvenile mice. 2014 Nov 7 2
18 23150428 Hepatic Cyp2d and Cyp26a1 mRNAs and activities are increased during mouse pregnancy. 2013 Feb 2
19 23385081 Accelerated degradation of retinoic acid by activated microglia. 2013 Mar 15 1
20 23638129 Regulation of retinoid-mediated signaling involved in skin homeostasis by RAR and RXR agonists/antagonists in mouse skin. 2013 1
21 23665324 Acetylcholine receptors regulate gene expression that is essential for primitive streak formation in murine embryoid bodies. 2013 Jun 7 2
22 23871845 Embryonic phenotype, β-carotene and retinoid metabolism upon maternal supplementation of β-carotene in a mouse model of severe vitamin A deficiency. 2013 Nov 15 2
23 24005908 The retinaldehyde reductase DHRS3 is essential for preventing the formation of excess retinoic acid during embryonic development. 2013 Dec 1
24 23053054 Retinoic acid synthesis and metabolism are concurrent in the mouse uterus during peri-implantation. 2012 Dec 2
25 21084447 Gene expression profiling reveals Cyp26b1 to be an activin regulated gene involved in ovarian granulosa cell proliferation. 2011 Jan 1
26 21148184 Vax2 regulates retinoic acid distribution and cone opsin expression in the vertebrate eye. 2011 Jan 1
27 21228214 Exposure to retinoic acid in the neonatal but not adult mouse results in synchronous spermatogenesis. 2011 May 2
28 21278145 Absence of hepatic stellate cell retinoid lipid droplets does not enhance hepatic fibrosis but decreases hepatic carcinogenesis. 2011 Sep 1
29 21504909 A clinical and experimental overview of sirenomelia: insight into the mechanisms of congenital limb malformations. 2011 May 1
30 21959331 The antitumor immunopreventive effects of a DNA vaccine against CYP26a1 on mouse breast carcinoma. 2011 Nov 8 1
31 19797313 A murine model of Denys-Drash syndrome reveals novel transcriptional targets of WT1 in podocytes. 2010 Jan 1 1
32 20112286 Retinoic acid-metabolizing enzyme cytochrome P450 26a1 (cyp26a1) is essential for implantation: functional study of its role in early pregnancy. 2010 May 6
33 20801112 Growth differentiation factor 11 signaling controls retinoic acid activity for axial vertebral development. 2010 Nov 1 1
34 20842651 The role of CYP26 enzymes in defining appropriate retinoic acid exposure during embryogenesis. 2010 Oct 4
35 19010342 Three conazoles increase hepatic microsomal retinoic acid metabolism and decrease mouse hepatic retinoic acid levels in vivo. 2009 Jan 15 1
36 19429397 Fluconazole alters CYP26 gene expression in mouse embryos. 2009 Apr 1
37 19556237 Cadmium induces retinoic acid signaling by regulating retinoic acid metabolic gene expression. 2009 Sep 11 1
38 19605690 Removal of maternal retinoic acid by embryonic CYP26 is required for correct Nodal expression during early embryonic patterning. 2009 Jul 15 5
39 17943179 Metabolism and biological activities of topical 4-oxoretinoids in mouse skin. 2008 Apr 1
40 18164278 Gene expression profiling elucidates a specific role for RARgamma in the retinoic acid-induced differentiation of F9 teratocarcinoma stem cells. 2008 Mar 1 1
41 18816858 Retinoic acid down-regulates Tbx1 expression and induces abnormal differentiation of tongue muscles in fetal mice. 2008 Oct 1
42 16955405 Regulation of expression of the retinoic acid metabolizing enzyme CYP26A1 in uteri of ovariectomized mice after treatment with ovarian steroid hormones. 2007 Feb 3
43 17010966 A role for the hypoblast (AVE) in the initiation of neural induction, independent of its ability to position the primitive streak. 2007 Jan 15 1
44 17067568 CYP26A1 and CYP26C1 cooperatively regulate anterior-posterior patterning of the developing brain and the production of migratory cranial neural crest cells in the mouse. 2007 Feb 15 1
45 17211890 The oxidizing enzyme CYP26a1 tightly regulates the availability of retinoic acid in the gastrulating mouse embryo to ensure proper head development and vasculogenesis. 2007 Mar 6
46 17486130 Molecular targeting of retinoic acid metabolism in neuroblastoma: the role of the CYP26 inhibitor R116010 in vitro and in vivo. 2007 Jun 4 3
47 16261163 RAR-mediated epigenetic control of the cytochrome P450 Cyp26a1 in embryocarcinoma cells. 2006 Mar 2 1
48 16461896 Retinoic acid regulates sex-specific timing of meiotic initiation in mice. 2006 Feb 21 1
49 16615129 Dynamic expression of retinoic acid-synthesizing and -metabolizing enzymes in the developing mouse inner ear. 2006 Jun 10 1
50 16688765 Retinoids, eye development, and maturation of visual function. 2006 Jun 2