| 1 |
33387654 | Biophysical and structural investigation of the regulation of human GTP cyclohydrolase I by its regulatory protein GFRP. | 2021 Mar |
4 |
| 2 |
33229582 | A hybrid approach reveals the allosteric regulation of GTP cyclohydrolase I. | 2020 Dec 15 |
1 |
| 3 |
26014146 | Validating the GTP-cyclohydrolase 1-feedback regulatory complex as a therapeutic target using biophysical and in vivo approaches. | 2015 Aug |
4 |
| 4 |
22633640 | Dyskinesias as a limiting factor in the treatment of Segawa disease. | 2012 Jun |
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| 5 |
21163945 | The N-terminal peptide of mammalian GTP cyclohydrolase I is an autoinhibitory control element and contributes to binding the allosteric regulatory protein GFRP. | 2011 Apr 8 |
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| 6 |
16778797 | GTP cyclohydrolase feedback regulatory protein controls cofactor 6-tetrahydrobiopterin synthesis in the cytosol and in the nucleus of epidermal keratinocytes and melanocytes. | 2006 Nov |
1 |
| 7 |
15946242 | Characterization of transgenic mice with the expression of phenylalanine hydroxylase and GTP cyclohydrolase I in the skin. | 2005 Jul |
2 |
| 8 |
15292175 | The mechanism of potent GTP cyclohydrolase I inhibition by 2,4-diamino-6-hydroxypyrimidine: requirement of the GTP cyclohydrolase I feedback regulatory protein. | 2004 Sep 24 |
1 |
| 9 |
15448133 | Structural basis of biopterin-induced inhibition of GTP cyclohydrolase I by GFRP, its feedback regulatory protein. | 2004 Dec 3 |
3 |
| 10 |
12607127 | Role of human GTP cyclohydrolase I and its regulatory protein in tetrahydrobiopterin metabolism. | 2003 Mar |
3 |
| 11 |
11799107 | Bacterial lipopolysaccharide down-regulates expression of GTP cyclohydrolase I feedback regulatory protein. | 2002 Mar 22 |
3 |
| 12 |
11818540 | Crystal structure of the stimulatory complex of GTP cyclohydrolase I and its feedback regulatory protein GFRP. | 2002 Feb 5 |
5 |
| 13 |
12208136 | Comparison of epidermal keratinocytes and dermal fibroblasts as potential target cells for somatic gene therapy of phenylketonuria. | 2002 Aug |
2 |
| 14 |
11274478 | Ligand binding to the inhibitory and stimulatory GTP cyclohydrolase I/GTP cyclohydrolase I feedback regulatory protein complexes. | 2001 Apr |
3 |
| 15 |
11175307 | Development of a skin-based metabolic sink for phenylalanine by overexpression of phenylalanine hydroxylase and GTP cyclohydrolase in primary human keratinocytes. | 2000 Dec |
3 |
| 16 |
9685352 | Decameric GTP cyclohydrolase I forms complexes with two pentameric GTP cyclohydrolase I feedback regulatory proteins in the presence of phenylalanine or of a combination of tetrahydrobiopterin and GTP. | 1998 Aug 7 |
3 |
| 17 |
8502995 | Feedback regulation mechanisms for the control of GTP cyclohydrolase I activity. | 1993 Jun 4 |
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