Phosphorylcholine

choline kinase alpha ; Homo sapiens







27 Article(s)
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Pub. Year
#Total Relationships
1 34985768 Crosstalk of FGFR1 signaling and choline metabolism promotes cell proliferation and survival in prostate cancer cells. 2022 May 1 2
2 31745227 Molecular basis for the interaction between human choline kinase alpha and the SH3 domain of the c-Src tyrosine kinase. 2019 Nov 19 1
3 29619216 Mutant IDH1 gliomas downregulate phosphocholine and phosphoethanolamine synthesis in a 2-hydroxyglutarate-dependent manner. 2018 2
4 28065789 Choline Kinase α Mediates Interactions Between the Epidermal Growth Factor Receptor and Mechanistic Target of Rapamycin Complex 2 in Hepatocellular Carcinoma Cells to Promote Drug Resistance and Xenograft Tumor Progression. 2017 Apr 2
5 28654865 Molecular Effects of Doxorubicin on Choline Metabolism in Breast Cancer. 2017 Aug 2
6 28704425 In vitro nuclear magnetic resonance spectroscopy metabolic biomarkers for the combination of temozolomide with PI3K inhibition in paediatric glioblastoma cells. 2017 1
7 27446799 Choline Metabolism Alteration: A Focus on Ovarian Cancer. 2016 1
8 27588131 CHKA mediates the poor prognosis of lung adenocarcinoma and acts as a prognostic indicator. 2016 Sep 2
9 27747192 Key Players in Choline Metabolic Reprograming in Triple-Negative Breast Cancer. 2016 2
10 25333818 Expression profiling of choline and ethanolamine kinases in MCF7, HCT116 and HepG2 cells, and the transcriptional regulation by epigenetic modification. 2015 Jan 4
11 26496360 Downregulation of Choline Kinase-Alpha Enhances Autophagy in Tamoxifen-Resistant Breast Cancer Cells. 2015 1
12 26503172 Choline kinase-α protein and phosphatidylcholine but not phosphocholine are required for breast cancer cell survival. 2015 Dec 2
13 24281000 Choline kinase-alpha by regulating cell aggressiveness and drug sensitivity is a potential druggable target for ovarian cancer. 2014 Jan 21 1
14 24556997 Phospholipase D1 and choline kinase-α are interactive targets in breast cancer. 2014 May 4
15 24287694 Choline kinase inhibition induces exacerbated endoplasmic reticulum stress and triggers apoptosis via CHOP in cancer cells. 2013 Nov 28 2
16 21822308 Functional interactions between Choline kinase α, epidermal growth factor receptor and c-Src in breast cancer cell proliferation. 2012 Mar 15 1
17 21423211 A novel small molecule antagonist of choline kinase-α that simultaneously suppresses MAPK and PI3K/AKT signaling. 2011 Jul 28 1
18 20623626 Choline kinase overexpression increases invasiveness and drug resistance of human breast cancer cells. 2010 Jul 5
19 19336572 Noninvasive detection of lentiviral-mediated choline kinase targeting in a human breast cancer xenograft. 2009 Apr 15 2
20 18029352 Early embryonic lethality caused by disruption of the gene for choline kinase alpha, the first enzyme in phosphatidylcholine biosynthesis. 2008 Jan 18 1
21 18172309 Hypoxia regulates choline kinase expression through hypoxia-inducible factor-1 alpha signaling in a human prostate cancer model. 2008 Jan 1 2
22 18056454 Choline kinase down-regulation increases the effect of 5-fluorouracil in breast cancer cells. 2007 Dec 1 4
23 16371353 A rostrocaudal muscular dystrophy caused by a defect in choline kinase beta, the first enzyme in phosphatidylcholine biosynthesis. 2006 Feb 24 2
24 20641747 [11C]Choline 2004 2
25 20641761 [18F]Fluorocholine 2004 2
26 21735582 [18F]Fluoro-[1,2-2H4]choline 2004 2
27 21735583 [18F]Fluoroethylcholine 2004 2