| 1 |
34273876 | Characterization of ASP8374, a fully-human, antagonistic anti-TIGIT monoclonal antibody. | 2021 |
1 |
| 2 |
24048955 | CD28 signaling in primary CD4(+) T cells: identification of both tyrosine phosphorylation-dependent and phosphorylation-independent pathways. | 2013 Dec |
1 |
| 3 |
22345277 | CD4+ T-cell dysfunctions through the impaired lipid rafts ameliorate concanavalin A-induced hepatitis in sphingomyelin synthase 1-knockout mice. | 2012 May |
1 |
| 4 |
21690296 | c-Abl-mediated tyrosine phosphorylation of the T-bet DNA-binding domain regulates CD4+ T-cell differentiation and allergic lung inflammation. | 2011 Aug |
2 |
| 5 |
20438120 | Quantitative phosphoproteomic analysis of T cell receptor signaling in diabetes prone and resistant mice. | 2010 Jun 4 |
1 |
| 6 |
19403707 | Vitamin E reverses impaired linker for activation of T cells activation in T cells from aged C57BL/6 mice. | 2009 Jun |
1 |
| 7 |
19682930 | Loss of the LAT adaptor converts antigen-responsive T cells into pathogenic effectors that function independently of the T cell receptor. | 2009 Aug 21 |
1 |
| 8 |
17963048 | Increased T-cell reactivity and elevated levels of CD8+ memory T-cells in Alzheimer's disease-patients and T-cell hyporeactivity in an Alzheimer's disease-mouse model: implications for immunotherapy. | 2007 |
1 |
| 9 |
18025205 | Role of STAT3 in CD4+CD25+FOXP3+ regulatory lymphocyte generation: implications in graft-versus-host disease and antitumor immunity. | 2007 Dec 1 |
1 |
| 10 |
15908443 | WSX-1 over-expression in CD4(+) T cells leads to hyperproliferation and cytokine hyperproduction in response to TCR stimulation. | 2005 Jul |
1 |
| 11 |
15577330 | Inhibition of melanoma growth after treatment with dendritic cells in a Tyr-SV40E murine model requires CD4+ T cells but not CD8+ T cells. | 2004 Dec |
1 |
| 12 |
12662296 | Altered proximal T-cell receptor signalling events in mouse CD4+ T cells in the presence of anti-CD4 monoclonal antibodies: evidence for reduced phosphorylation of Zap-70 and LAT. | 2003 Apr |
2 |
| 13 |
14515253 | Development of T cells expressing an altered TCR complex. | 2003 Oct |
1 |
| 14 |
10903722 | Age-dependent alterations in the assembly of signal transduction complexes at the site of T cell/APC interaction. | 2000 Aug 1 |
2 |
| 15 |
11086073 | Desensitization of CXC chemokine receptor 4, mediated by IL-16/CD4, is independent of p56lck enzymatic activity. | 2000 Dec 1 |
2 |
| 16 |
10448009 | Antibody-induced CD3-CD4 coligation inhibits TCR/CD3 activation in the absence of costimulatory signals in normal mouse CD4(+) T lymphocytes. | 1999 Aug 1 |
2 |
| 17 |
10477569 | Effector CD4 T cells are biochemically distinct from the memory subset: evidence for long-term persistence of effectors in vivo. | 1999 Sep 15 |
1 |
| 18 |
10586049 | Ability of a nondepleting anti-CD4 antibody to inhibit Th2 responses and allergic lung inflammation is independent of coreceptor function. | 1999 Dec 15 |
1 |
| 19 |
9557951 | Signalling initiated with CD4-TCR or TCR-TCR interactions: comparison of tyrosine phosphorylation patterns and CD45 effects. | 1998 Feb |
1 |
| 20 |
9015188 | Differential tyrosine phosphorylation of zeta chain dimers in mouse CD4 T lymphocytes: effect of age. | 1997 Jan 10 |
3 |
| 21 |
9042429 | CD4 dependence of activation threshold and TCR signalling in mouse T lymphocytes. | 1997 Feb |
4 |
| 22 |
8855300 | Fas (CD95) expression and death-mediating function are induced by CD4 cross-linking on CD4+ T cells. | 1996 Oct 1 |
1 |
| 23 |
8915030 | Abnormal signal transduction through CD4 leads to altered tyrosine phosphorylation in T cells derived from MRL-lpr/lpr mice. | 1996 |
2 |
| 24 |
7564569 | Rapid tyrosine phosphorylation of Grb2 and Shc in T cells exposed to anti-CD3, anti-CD4, and anti-CD45 stimuli: differential effects of aging. | 1995 Jun 9 |
1 |
| 25 |
7614232 | Activation of murine T-cells via phospholipase-C gamma 1-associated protein tyrosine phosphorylation is reduced with aging. | 1995 Jul |
1 |
| 26 |
7510235 | Reversal of hyporesponsiveness in lpr CD4-CD8- T cells is achieved by induction of cell cycling and normalization of CD2 and p59fyn expression. | 1994 Mar |
1 |
| 27 |
7835966 | CD4-independent signal transduction through the T-cell receptor (TCR/CD3). | 1994 Nov |
2 |
| 28 |
7929062 | Requirement for kinase activity of CD4-associated p56lck in antibody-triggered T cell signal transduction. | 1994 Sep 30 |
1 |
| 29 |
8294879 | Evidence for differential intracellular signaling via CD4 and CD8 molecules. | 1994 Feb 1 |
1 |
| 30 |
8103063 | Reduced CD3-mediated protein tyrosine phosphorylation in anergic CD4+ and CD8+ T cells. | 1993 Sep 1 |
2 |
| 31 |
8335907 | CD8 inhibits signal transduction through the T cell receptor in CD4-CD8- thymocytes from T cell receptor transgenic mice reconstituted with a transgenic CD8 alpha molecule. | 1993 Jul 15 |
1 |
| 32 |
1311423 | Product of vav proto-oncogene defines a new class of tyrosine protein kinase substrates. | 1992 Mar 5 |
1 |
| 33 |
1706070 | Enhancement of T-cell responsiveness by the lymphocyte-specific tyrosine protein kinase p56lck. | 1991 Mar 7 |
3 |
| 34 |
1706380 | CD4 and CD8 are positive regulators of T cell receptor signal transduction in early T cell differentiation. | 1991 Mar 15 |
1 |
| 35 |
2118992 | Cross-linking of T-cell surface molecules CD4 and CD8 stimulates phosphorylation of the lck tyrosine protein kinase at the autophosphorylation site. | 1990 Oct |
3 |
| 36 |
2250907 | The CD4 associated tyrosine protein kinase p56lck is positively regulated through its site of autophosphorylation. | 1990 Oct |
4 |
| 37 |
2557544 | Tyrosine phosphorylation of a c-Src-like protein is increased in membranes of CD4- CD8- T lymphocytes from lpr/lpr mice. | 1989 Nov |
2 |