| 1 |
35034963 | Association of ITPA gene polymorphisms with adverse effects of AZA/6-MP administration: a systematic review and meta-analysis. | 2022 Feb |
2 |
| 2 |
35159194 | Inosine Triphosphate Pyrophosphatase (ITPase): Functions, Mutations, Polymorphisms and Its Impact on Cancer Therapies. | 2022 Jan 24 |
1 |
| 3 |
34720526 | Biomarkers for gastrointestinal adverse events related to thiopurine therapy. | 2021 Oct 14 |
1 |
| 4 |
32124692 | Clinical Application of Thiopurine Pharmacogenomics in Pediatrics. | 2020 |
1 |
| 5 |
32372428 | Effects of various genetic polymorphisms on thiopurine treatment-associated outcomes for Korean patients with Crohn's disease. | 2020 Nov |
1 |
| 6 |
31639757 | Retrospective Data Analysis of the Influence of Age and Sex on TPMT Activity and Its Phenotype-Genotype Correlation. | 2019 Mar |
2 |
| 7 |
29327413 | ITPA Activity in Children Treated by Azathioprine: Relationship to the Occurrence of Adverse Drug Reactions and Inflammatory Response. | 2018 Jun |
2 |
| 8 |
30086084 | Distribution of Genetic Polymorphisms of Genes Implicated in Thiopurine Drugs Metabolism. | 2018 Oct |
2 |
| 9 |
28650902 | ITPA Activity in Adults and Children Treated With or Without Azathioprine: Relationship Between TPMT Activity, Thiopurine Metabolites, and Co-medications. | 2017 Oct |
5 |
| 10 |
28963908 | Emerging role of NUDT15 polymorphisms in 6-mercaptopurine metabolism and dose related toxicity in acute lymphoblastic leukaemia. | 2017 Nov |
1 |
| 11 |
27307154 | A Simple Method for TPMT and ITPA Genotyping Using Multiplex HRMA for Patients Treated with Thiopurine Drugs. | 2016 Oct |
4 |
| 12 |
27770805 | A disease spectrum for ITPA variation: advances in biochemical and clinical research. | 2016 Oct 22 |
3 |
| 13 |
22384212 | Pivotal role of inosine triphosphate pyrophosphatase in maintaining genome stability and the prevention of apoptosis in human cells. | 2012 |
1 |
| 14 |
22673202 | Determination of inosine triphosphate pyrophosphatase phenotype in human red blood cells using HPLC. | 2012 Aug |
3 |
| 15 |
23335936 | Multilocus genotypes of relevance for drug metabolizing enzymes and therapy with thiopurines in patients with acute lymphoblastic leukemia. | 2012 |
1 |
| 16 |
22060550 | The effect of ITPA polymorphisms on the enzyme kinetic properties of human erythrocyte inosine triphosphatase toward its substrates ITP and 6-Thio-ITP. | 2011 Nov |
4 |
| 17 |
18685564 | Genetic polymorphism of inosine triphosphate pyrophosphatase is a determinant of mercaptopurine metabolism and toxicity during treatment for acute lymphoblastic leukemia. | 2009 Feb |
2 |
| 18 |
19579612 | Allele frequency of thiopurine methyltransferase and inosine triphosphate pyrophosphatase gene polymorphisms in Korean patients with inflammatory bowel diseases. | 2009 Mar-Apr |
1 |
| 19 |
18090994 | Thiopurine-methyltransferase and inosine triphosphate pyrophosphatase polymorphism in a liver transplant recipient developing nodular regenerative hyperplasia on low-dose azathioprine. | 2008 Jan |
2 |
| 20 |
18223458 | Characterization of the inosine triphosphatase (ITPA) gene: haplotype structure, haplotype-phenotype correlation and promoter function. | 2008 Feb |
2 |
| 21 |
18506437 | Clinical pharmacology and pharmacogenetics of thiopurines. | 2008 Aug |
2 |
| 22 |
18600522 | ITPase activity in dry blood spots is comparable with that in fresh erythrocytes. | 2008 Jun |
3 |
| 23 |
17113761 | The ITPA c.94C>A and g.IVS2+21A>C sequence variants contribute to missplicing of the ITPA gene. | 2007 Jan |
1 |
| 24 |
17697198 | Meta-analysis: Inosine triphosphate pyrophosphatase polymorphisms and thiopurine toxicity in the treatment of inflammatory bowel disease. | 2007 Sep 1 |
6 |
| 25 |
17924837 | Pharmacogenetic significance of inosine triphosphatase. | 2007 Sep |
2 |
| 26 |
29783434 | Typing TPMT and ITPase to detect azathioprine toxicity. | 2006 Feb |
2 |
| 27 |
15946879 | Genetic basis of inosine triphosphate pyrophosphohydrolase deficiency in the Japanese population. | 2005 Aug |
3 |
| 28 |
16214825 | Association of inosine triphosphatase 94C>A and thiopurine S-methyltransferase deficiency with adverse events and study drop-outs under azathioprine therapy in a prospective Crohn disease study. | 2005 Dec |
2 |
| 29 |
15571266 | Allele frequency of inosine triphosphate pyrophosphatase gene polymorphisms in a Japanese population. | 2004 Oct |
1 |