Tyrosine

platelet derived growth factor receptor beta ; Homo sapiens







90 Article(s)
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Pub. Year
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1 33655823 Natural Sourced Inhibitors of EGFR, PDGFR, FGFR and VEGFRMediated Signaling Pathways as Potential Anticancer Agents. 2022 1
2 34144039 Platelet-derived growth factor receptor beta activates Abl2 via direct binding and phosphorylation. 2021 Jul 1
3 34360683 Syndecan Transmembrane Domain Specifically Regulates Downstream Signaling Events of the Transmembrane Receptor Cytoplasmic Domain. 2021 Jul 24 2
4 31645680 The incidence, genetic characteristics, and prognosis of leukemia with concurrent pathogenic fusion genes: a series of 25 cases from a large cohort of leukemia patients. 2020 Feb 1
5 30573803 A tyrosine kinase-activating variant Asn666Ser in PDGFRB causes a progeria-like condition in the severe end of Penttinen syndrome. 2019 Apr 1
6 31794427 Ninjurin2 overexpression promotes glioma cell growth. 2019 Dec 2 1
7 31934053 Rearrangement of PDGFRβ gene in a patient with Ph-negative chronic myeloid leukemia t(5;12)(q33;p13) in imatinib mesylate treatment-free remission: a case report. 2019 1
8 28661054 Platelet-derived growth factor regulates YAP transcriptional activity via Src family kinase dependent tyrosine phosphorylation. 2018 Jan 1
9 28726812 A patient with germ-line gain-of-function PDGFRB p.N666H mutation and marked clinical response to imatinib. 2018 Jan 1
10 28951244 Tyrosines-740/751 of PDGFRβ contribute to the activation of Akt/Hif1α/TGFβ nexus to drive high glucose-induced glomerular mesangial cell hypertrophy. 2018 Jan 3
11 31723781 Advances in B-cell Precursor Acute Lymphoblastic Leukemia Genomics. 2018 Aug 1
12 27048651 The Ubiquitin Ligases c-Cbl and Cbl-b Negatively Regulate Platelet-derived Growth Factor (PDGF) BB-induced Chemotaxis by Affecting PDGF Receptor β (PDGFRβ) Internalization and Signaling. 2016 May 27 2
13 27293031 Imatinib and Nilotinib increase glioblastoma cell invasion via Abl-independent stimulation of p130Cas and FAK signalling. 2016 Jun 13 2
14 27791986 Human airway smooth muscle cell proliferation from asthmatics is negatively regulated by semaphorin3A. 2016 Dec 6 1
15 25257795 PDGFR-β-activated ACK1-AKT signaling promotes glioma tumorigenesis. 2015 Apr 15 1
16 25298192 Targeting receptor tyrosine kinases and their downstream signaling with cell-penetrating peptides in human pulmonary artery smooth muscle and endothelial cells. 2015 May 1
17 25819339 PDGF-D signaling in portal myofibroblasts and hepatic stellate cells proves identical to PDGF-B via both PDGF receptor type α and β. 2015 Jul 1
18 24695376 Inhibitory effect of a novel naphthoquinone derivative on proliferation of vascular smooth muscle cells through suppression of platelet-derived growth factor receptor β tyrosine kinase. 2014 Jun 15 1
19 23441134 PDGFRB promotes liver metastasis formation of mesenchymal-like colorectal tumor cells. 2013 Feb 1
20 23583652 Pazopanib inhibits the activation of PDGFRβ-expressing astrocytes in the brain metastatic microenvironment of breast cancer cells. 2013 Jun 1
21 23589302 The Fer tyrosine kinase is important for platelet-derived growth factor-BB-induced signal transducer and activator of transcription 3 (STAT3) protein phosphorylation, colony formation in soft agar, and tumor growth in vivo. 2013 May 31 4
22 23922991 The LDL receptor-related protein 1 (LRP1) regulates the PDGF signaling pathway by binding the protein phosphatase SHP-2 and modulating SHP-2- mediated PDGF signaling events. 2013 1
23 21866565 Direct modulation of the protein kinase A catalytic subunit α by growth factor receptor tyrosine kinases. 2012 Jan 2
24 23047550 Vascular endothelial growth factor signals through platelet-derived growth factor receptor β in meningiomas in vitro. 2012 Nov 6 3
25 21760611 The death receptor CD95 activates the cofilin pathway to stimulate tumour cell invasion. 2011 Sep 1 1
26 21813417 Western blotting via proximity ligation for high performance protein analysis. 2011 Nov 1
27 20049867 Global phosphoproteomic effects of natural tyrosine kinase inhibitor, genistein, on signaling pathways. 2010 Mar 1
28 20494825 Mutation of tyrosine residue 857 in the PDGF beta-receptor affects cell proliferation but not migration. 2010 Sep 2
29 19074160 Differential effects of red and white wines on inhibition of the platelet-derived growth factor receptor: impact of the mash fermentation. 2009 Mar 1 1
30 19082496 The platelet-derived growth factor receptor as a target for vascular endothelial growth factor-mediated anti-angiogenetic therapy in head and neck cancer. 2009 Jan 1
31 19092051 Reciprocal regulation of the platelet-derived growth factor receptor-beta and G protein-coupled receptor kinase 5 by cross-phosphorylation: effects on catalysis. 2009 Mar 3
32 19100521 Tel/PDGFRbeta induces stem cell differentiation via the Ras/ERK and STAT5 signaling pathways. 2009 Jan 2
33 19225164 Preadipocyte apoptosis is prevented by macrophage-conditioned medium in a PDGF-dependent manner. 2009 Apr 2
34 19275932 Reciprocal regulation of Abl and receptor tyrosine kinases. 2009 Jul 1
35 17991872 TF/FVIIa transactivate PDGFRbeta to regulate PDGF-BB-induced chemotaxis in different cell types: involvement of Src and PLC. 2008 Jan 2
36 18567737 Resveratrol inhibits PDGF receptor mitogenic signaling in mesangial cells: role of PTP1B. 2008 Oct 3
37 17452978 KIT oncoprotein interactions in gastrointestinal stromal tumors: therapeutic relevance. 2007 Sep 27 1
38 17545600 Platelet-derived growth factor receptor beta-mediated phosphorylation of MUC1 enhances invasiveness in pancreatic adenocarcinoma cells. 2007 Jun 1 2
39 17558420 Imatinib mesylate inhibits cell invasion of malignant peripheral nerve sheath tumor induced by platelet-derived growth factor-BB. 2007 Aug 1
40 17565975 In situ detection of phosphorylated platelet-derived growth factor receptor beta using a generalized proximity ligation method. 2007 Sep 4
41 17961557 TGFbeta intercepts nuclear glycogen synthase kinase 3beta to inhibit PDGF-induced DNA synthesis in mesangial cells. 2007 Nov 13 1
42 16377635 The smaller isoforms of ankyrin 3 bind to the p85 subunit of phosphatidylinositol 3'-kinase and enhance platelet-derived growth factor receptor down-regulation. 2006 Mar 3 2
43 16530387 c-Src couples PI 3 kinase/Akt and MAPK signaling to PDGF-induced DNA synthesis in mesangial cells. 2006 Nov 1
44 16569213 Angiotensin II stimulates phosphorylation of an ectodomain-truncated platelet-derived growth factor receptor-beta and its binding to class IA PI3K in vascular smooth muscle cells. 2006 Jul 15 1
45 16763682 Structure-activity studies on a library of potent calix[4]arene-based PDGF antagonists that inhibit PDGF-stimulated PDGFR tyrosine phosphorylation. 2006 Jun 21 1
46 16790699 Stimulatory autoantibodies to the PDGF receptor in systemic sclerosis. 2006 Jun 22 1
47 16876267 Acceleration of matrix metalloproteinase-1 production and activation of platelet-derived growth factor receptor beta in human coronary smooth muscle cells by oxidized LDL and 4-hydroxynonenal. 2006 Aug 2
48 16930548 Fluorescence lifetime imaging microscopy (FLIM) detects stimulus-dependent phosphorylation of the low density lipoprotein receptor-related protein (LRP) in primary neurons. 2006 Oct 13 1
49 15641795 NMR dynamics-derived insights into the binding properties of a peptide interacting with an SH2 domain. 2005 Jan 18 2
50 15763428 A-Raf associates with and regulates platelet-derived growth factor receptor signalling. 2005 Jul 1