Cocaine

carboxylesterase 2 ; Homo sapiens







18 Article(s)
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Pub. Year
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1 34761870 Cocaine esterase occurrence in global wastewater microbiomes and potential for biotransformation of novel psychoactive substances. 2022 Feb 1
2 33013487 Efficient Cocaine Degradation by Cocaine Esterase-Loaded Red Blood Cells. 2020 2
3 27224254 Metabolic Enzymes of Cocaine Metabolite Benzoylecgonine. 2016 Aug 19 2
4 28250715 Reaction Pathway for Cocaine Hydrolase-Catalyzed Hydrolysis of (+)-Cocaine. 2016 Jan 2
5 23978563 Experimental treatments for cocaine toxicity: a difficult transition to the bedside. 2013 Nov 1
6 22385120 Cocaine esterase-cocaine binding process and the free energy profiles by molecular dynamics and potential of mean force simulations. 2012 Mar 15 3
7 22404344 Cell permeable cocaine esterases constructed by chemical conjugation and genetic recombination. 2012 May 7 2
8 21373712 Computational design of a thermostable mutant of cocaine esterase via molecular dynamics simulations. 2011 Jun 7 2
9 21486046 Reaction mechanism for cocaine esterase-catalyzed hydrolyses of (+)- and (-)-cocaine: unexpected common rate-determining step. 2011 May 5 14
10 19857534 PEGylation of bacterial cocaine esterase for protection against protease digestion and immunogenicity. 2010 Mar 3 8
11 20436035 Structural analysis of thermostabilizing mutations of cocaine esterase. 2010 Jul 4
12 20649590 Biochemical and molecular analysis of carboxylesterase-mediated hydrolysis of cocaine and heroin. 2010 Aug 1
13 18987161 Thermostable variants of cocaine esterase for long-time protection against cocaine toxicity. 2009 Feb 7
14 19478136 Lasting reduction of cocaine action in neostriatum--a hydrolase gene therapy approach. 2009 Aug 3
15 19642701 Fundamental reaction mechanism and free energy profile for (-)-cocaine hydrolysis catalyzed by cocaine esterase. 2009 Aug 26 4
16 10381793 Binding and hydrolysis of meperidine by human liver carboxylesterase hCE-1. 1999 Jul 1
17 9169443 Purification and cloning of a broad substrate specificity human liver carboxylesterase that catalyzes the hydrolysis of cocaine and heroin. 1997 Jun 6 3
18 8930175 Metabolism of cocaine and heroin is catalyzed by the same human liver carboxylesterases. 1996 Nov 2