Alanine

interleukin 2 ; Homo sapiens







27 Article(s)
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1 24955549 High-level expression, purification and study of bioactivity of fusion protein M-IL-2((88)Arg, (125)Ala) in Pichia pastoris. 2014 Sep 1
2 25451252 Optimization protein productivity of human interleukin-2 through codon usage, gene copy number and intracellular tRNA concentration in CHO cells. 2014 Nov 14 2
3 23484211 Short cell-penetrating peptides: a model of interactions with gene promoter sites. 2013 Jan 1
4 17872379 Contributions of intracellular loops 2 and 3 of the lutropin receptor in Gs coupling. 2008 Jan 1
5 17502353 Phosphorylation of Bcl10 negatively regulates T-cell receptor-mediated NF-kappaB activation. 2007 Jul 1
6 16622285 Expression and purification of a mutant of human interleukin-2 in Pichia pastoris. 2006 Apr 2
7 15638990 Stability of Ala 125 recombinant human interleukin-2 in solution. 2005 Jan 2
8 16108369 [Studies on fermentation conditions and purification of mutant human interleukin-2 expressed in Pichia pastoris]. 2005 May 1
9 15004204 HLA-DQ8-associated T cell responses to the diabetes autoantigen phogrin (IA-2 beta) in human prediabetes. 2004 Mar 15 1
10 12350108 Isolation and characterization of modified species of a mutated (Cys125 -Ala) recombinant human interleukin-2. 2002 Sep 20 1
11 9144530 Structural modifications of interleukin-2 at positions 47 and 65. 1997 Apr 17 1
12 7636534 Adoptive immunotherapy with tumor-infiltrating lymphocytes and interleukin-2 in patients with metastatic malignant melanoma and renal cell carcinoma: a pilot study. 1995 Aug 2
13 8588953 Pharmacokinetic, pharmacodynamic, and pharmacotoxic profiles of recombinant-methionyl human interleukin-2[alanine-125] (r-metHuIL-2[ala-125]) following intravenous and subcutaneous administration in rats. 1995 Nov 2
14 2009236 Blood coagulation abnormalities during adoptive immunotherapy with interleukin-2 (r-Met Hu IL-2 [ala 125]). 1991 Jan 3
15 2208578 Pharmacokinetics of repeated i.v. bolus administration of high doses of r-met-Hu interleukin-2 in advanced cancer patients. 1990 2
16 2319262 A pilot study of intralymphatic interleukin-2. II. Clinical and biological effects. 1990 Feb 1
17 2351778 Haemodynamic effects induced by intravenous administration of high doses of r-Met Hu IL-2 [ala-125] in patients with advanced cancer. 1990 2
18 2784163 Systemic administration of recombinant methionyl human interleukin-2 (Ala 125) to cancer patients: clinical results. 1989 Feb 1
19 2787749 Tolerance and effectiveness of recombinant interleukin-2 (r-met Hu IL-2 [ala-125]) and lymphokine-activated killer cells in patients with metastatic solid tumors. 1989 Jun 1
20 2461206 Modifications of plasma lipids, lipoproteins and apolipoproteins in advanced cancer patients treated with recombinant interleukin-2 and autologous lymphokine-activated killer cells. 1988 Oct 2
21 2851586 High-level expression of human BSF-2/IL-6 cDNA in Escherichia coli using a new type of expression-preparation system. 1988 Jul 1
22 3066670 Construction, purification and biological activities of recombinant human interleukin-2 analogs. 1988 2
23 3258574 Stimulation of growth of Nb2 lymphoma cells by interleukin-2 in serum-free and serum-containing media. 1988 Feb 2
24 3116720 Binding, uptake and degradation of human recombinant interleukin-2 (125 ala) in activated human T- and B-lymphocytes and in monocyte-macrophages. 1987 May 3
25 3485976 Separation of recombinant human interleukin-2 and methionyl interleukin-2 produced in Escherichia coli. 1986 Mar 28 5
26 3489566 Suppression of cytotoxic T-lymphocyte activation by pyruvate and L-alanine. 1986 May 1
27 3491089 The development of anti-interleukin-2 antibodies in patients treated with recombinant human interleukin-2 (IL-2). 1986 Nov 1