| 1 |
35048565 | Pyruvate Facilitates FACT-Mediated γH2AX Loading to Chromatin and Promotes the Radiation Resistance of Glioblastoma. | 2022 Mar |
2 |
| 2 |
35189247 | Objective assessment of adrenocortical carcinoma driver genes and their correlation with tumor pyruvate kinase M2. | 2022 May 15 |
4 |
| 3 |
35610475 | Pyruvate kinase M1 regulates butyrate metabolism in cancerous colonocytes. | 2022 May 24 |
2 |
| 4 |
33473116 | SUMOylation disassembles the tetrameric pyruvate kinase M2 to block myeloid differentiation of leukemia cells. | 2021 Jan 20 |
1 |
| 5 |
33526685 | Absence of retbindin blocks glycolytic flux, disrupts metabolic homeostasis, and leads to photoreceptor degeneration. | 2021 Feb 9 |
2 |
| 6 |
33901643 | Discovery of boronic acid-based potent activators of tumor pyruvate kinase M2 and development of gastroretentive nanoformulation for oral dosing. | 2021 Jun 15 |
2 |
| 7 |
34355179 | Tumor pyruvate kinase M2 modulators: a comprehensive account of activators and inhibitors as anticancer agents. | 2021 Jul 21 |
4 |
| 8 |
32208360 | Endometrial pyruvate kinase M2 is essential for decidualization during early pregnancy. | 2020 Jun |
2 |
| 9 |
31880514 | Glucose restriction reverses the Warburg effect and modulates PKM2 and mTOR expression in breast cancer cell lines. | 2019 Sep 30 |
2 |
| 10 |
30087897 | Tyrosine Kinase Signaling in Cancer Metabolism: PKM2 Paradox in the Warburg Effect. | 2018 |
2 |
| 11 |
30700935 | Tumor pyruvate kinase M2: A promising molecular target of gastrointestinal cancer. | 2018 Dec |
4 |
| 12 |
29182273 | Structural Investigation of a Dimeric Variant of Pyruvate Kinase Muscle Isoform 2. | 2017 Dec 19 |
2 |
| 13 |
29312595 | Pyruvate kinase M2 phosphorylates H2AX and promotes genomic instability in human tumor cells. | 2017 Dec 12 |
1 |
| 14 |
27152240 | Extracellular PKM2 induces cancer proliferation by activating the EGFR signaling pathway. | 2016 |
1 |
| 15 |
27810895 | A Novel Role for Pyruvate Kinase M2 as a Corepressor for P53 during the DNA Damage Response in Human Tumor Cells. | 2016 Dec 9 |
1 |
| 16 |
25645022 | Structural insight into mechanisms for dynamic regulation of PKM2. | 2015 Apr |
4 |
| 17 |
23576436 | Reciprocal regulation of protein kinase and pyruvate kinase activities of pyruvate kinase M2 by growth signals. | 2013 May 31 |
2 |
| 18 |
22306293 | Pyruvate kinase M2 regulates gene transcription by acting as a protein kinase. | 2012 Mar 9 |
6 |
| 19 |
22262476 | Metabolic pathway alterations that support cell proliferation. | 2011 |
1 |
| 20 |
20847263 | Evidence for an alternative glycolytic pathway in rapidly proliferating cells. | 2010 Sep 17 |
2 |
| 21 |
18298799 | Modulation of M2-type pyruvate kinase activity by the cytoplasmic PML tumor suppressor protein. | 2008 Mar |
1 |