Prostaglandins

arachidonate 5-lipoxygenase ; Homo sapiens







25 Article(s)
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Pub. Year
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1 34401905 Eicosanoid receptors as therapeutic targets for asthma. 2021 Aug 27 2
2 34411565 Role of eicosanoids in liver repair, regeneration and cancer. 2021 Oct 1
3 35126121 Inhibitors of Human 5-Lipoxygenase Potently Interfere With Prostaglandin Transport. 2021 1
4 30735438 Targeting biosynthetic networks of the proinflammatory and proresolving lipid metabolome. 2019 May 3
5 26541818 The natural dual cyclooxygenase and 5-lipoxygenase inhibitor flavocoxid is protective in EAE through effects on Th1/Th17 differentiation and macrophage/microglia activation. 2016 Mar 1
6 24396479 Study of the polymorphisms of cyclooxygenase-2 (-765G>C) and 5-lipoxygenase (1708G>A) in patients with colorectal cancer. 2014 Feb 2
7 23956046 Regulation of genes in the arachidonic acid metabolic pathway by RNA processing and RNA-mediated mechanisms. 2013 Sep-Oct 1
8 21482803 Biosynthesis of hemiketal eicosanoids by cross-over of the 5-lipoxygenase and cyclooxygenase-2 pathways. 2011 Apr 26 2
9 20378604 Epoxyeicosatrienoates are the dominant eicosanoids in human lungs upon microbial challenge. 2010 Nov 1
10 20454765 Resolution of adipose tissue inflammation. 2010 May 4 2
11 20880396 The 5-lipoxygenase inhibitor, zileuton, suppresses prostaglandin biosynthesis by inhibition of arachidonic acid release in macrophages. 2010 Oct 1
12 18829119 Blockade of cytosolic phospholipase A2 alpha prevents experimental autoimmune encephalomyelitis and diminishes development of Th1 and Th17 responses. 2008 Nov 15 1
13 18991687 Pro-inflammatory gene variants in myocardial infarction and longevity: implications for pharmacogenomics. 2008 2
14 16417352 Convergent oxygenation of arachidonic acid by 5-lipoxygenase and cyclooxygenase-2. 2006 Jan 25 1
15 16537708 Prostacyclin synthase and arachidonate 5-lipoxygenase polymorphisms and risk of colorectal polyps. 2006 Mar 2
16 16968946 Eicosanoid transcellular biosynthesis: from cell-cell interactions to in vivo tissue responses. 2006 Sep 1
17 17156456 The shunt from the cyclooxygenase to lipoxygenase pathway in human osteoarthritic subchondral osteoblasts is linked with a variable expression of the 5-lipoxygenase-activating protein. 2006 1
18 15060721 Dual inhibition of 5-lipoxygenase/cyclooxygenase by a reconstituted homeopathic remedy; possible explanation for clinical efficacy and favourable gastrointestinal tolerability. 2004 Apr 1
19 12496393 Prostaglandins inhibit 5-lipoxygenase-activating protein expression and leukotriene B4 production from dendritic cells via an IL-10-dependent mechanism. 2003 Jan 1 1
20 12767056 Cdc42 and RhoA are differentially regulated during arachidonate-mediated HeLa cell adhesion. 2003 Jul 1
21 14518558 The metabolic effects of inhibitors of 5-lipoxygenase and of cyclooxygenase 1 and 2 are an advancement in the efficacy and safety of anti-inflammatory therapy. 2003 Jul 2
22 10759916 Montelukast in the prophylaxis of migraine: a potential role for leukotriene modifiers. 2000 Feb 1
23 10877840 Putative role of neuronal 5-lipoxygenase in an aging brain. 2000 Jul 1
24 8498522 Transcellular eicosanoid synthesis in cocultures of alveolar epithelial cells and macrophages. 1993 May 1
25 2128178 Effects of novel antifungal azole derivatives on the 5-lipoxygenase and cyclooxygenase pathway. 1990 Nov 1