Copper

Cu(2+)-transporting P-type ATPase CCC2 ; Saccharomyces cerevisiae S288C







38 Article(s)
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1 35563497 Yeast as a Model to Find New Drugs and Drug Targets for VPS13-Dependent Neurodegenerative Diseases. 2022 May 4 1
2 33116258 Dynamic transcriptional response of Saccharomyces cerevisiae cells to copper. 2020 Oct 28 3
3 29740406 Two P1B-1-ATPases of Amanita strobiliformis With Distinct Properties in Cu/Ag Transport. 2018 2
4 26275420 Influence of Ogg1 repair on the genetic stability of ccc2 mutant of Saccharomyces cerevisiae chemically challenged with 4-nitroquinoline-1-oxide (4-NQO). 2016 Jan 1
5 27401861 Transcriptomic response of yeast cells to ATX1 deletion under different copper levels. 2016 Jul 11 2
6 26004889 Functional characterization of new mutations in Wilson disease gene (ATP7B) using the yeast model. 2015 2
7 24056782 Transcriptional remodelling in response to changing copper levels in the Wilson and Menkes disease model of Saccharomyces cerevisiae. 2013 Nov 2
8 21163943 Two serine residues control sequential steps during catalysis of the yeast copper ATPase through different mechanisms that involve kinase-mediated phosphorylations. 2011 Mar 4 2
9 19678841 Dissecting the role of the N-terminal metal-binding domains in activating the yeast copper ATPase in vivo. 2009 Aug 14
10 18203200 Sequence variation in the ATP-binding domain of the Wilson disease transporter, ATP7B, affects copper transport in a yeast model system. 2008 Apr 2
11 17961510 Interaction of the two soluble metal-binding domains of yeast Ccc2 with copper(I)-Atx1. 2007 Dec 21 2
12 16946276 Mechanisms of copper loading on the Schizosaccharomyces pombe copper amine oxidase 1 expressed in Saccharomyces cerevisiae. 2006 Sep 1
13 17013682 Mapping protein-protein interaction by 13C'-detected heteronuclear NMR spectroscopy. 2006 Oct 1
14 15710399 Cd2+- or Hg2+-binding proteins can replace the Cu+-chaperone Atx1 in delivering Cu+ to the secretory pathway in yeast. 2005 Feb 14 4
15 15963506 Purification and functional reconstitution of the human Wilson copper ATPase, ATP7B. 2005 Jul 4 1
16 14962673 Functional assessment of the carboxy-terminus of the Wilson disease copper-transporting ATPase, ATP7B. 2004 Mar 1
17 14993228 Copper and iron are the limiting factors for growth of the yeast Saccharomyces cerevisiae in an alkaline environment. 2004 May 7 1
18 15012137 C-terminal domain of the membrane copper transporter Ctr1 from Saccharomyces cerevisiae binds four Cu(I) ions as a cuprous-thiolate polynuclear cluster: sub-femtomolar Cu(I) affinity of three proteins involved in copper trafficking. 2004 Mar 17 1
19 15062089 A docking approach to the study of copper trafficking proteins; interaction between metallochaperones and soluble domains of copper ATPases. 2004 Apr 3
20 15078884 A mutational study in the transmembrane domain of Ccc2p, the yeast Cu(I)-ATPase, shows different roles for each Cys-Pro-Cys cysteine. 2004 Jun 18 3
21 15147898 Complementation of Saccharomyces cerevisiae ccc2 mutant by a putative P1B-ATPase from Brassica napus supports a copper-transporting function. 2004 May 21 1
22 15381069 Copper-dependent protein-protein interactions studied by yeast two-hybrid analysis. 2004 Oct 22 2
23 12572677 Copper-induced trafficking of the cU-ATPases: a key mechanism for copper homeostasis. 2003 Mar 2
24 12921533 Functional studies of hephaestin in yeast: evidence for multicopper oxidase activity in the endocytic pathway. 2003 Nov 1 1
25 11083871 Solution structure of the yeast copper transporter domain Ccc2a in the apo and Cu(I)-loaded states. 2001 Mar 16 3
26 10764731 Energetics of copper trafficking between the Atx1 metallochaperone and the intracellular copper transporter, Ccc2. 2000 Jun 23 2
27 10942420 Copper-dependent trafficking of Wilson disease mutant ATP7B proteins. 2000 Aug 12 1
28 10079832 Intracellular pathways of copper trafficking in yeast and humans. 1999 2
29 10329707 Structure-function analyses of the ATX1 metallochaperone. 1999 May 21 3
30 10404590 Crystal structure of the Atx1 metallochaperone protein at 1.02 A resolution. 1999 Jun 15 2
31 9452509 Functional expression of the menkes disease protein reveals common biochemical mechanisms among the copper-transporting P-type ATPases. 1998 Feb 6 2
32 9654149 Analysis of functional domains of Wilson disease protein (ATP7B) in Saccharomyces cerevisiae. 1998 May 29 1
33 9837819 Functional characterization of missense mutations in ATP7B: Wilson disease mutation or normal variant? 1998 Dec 1
34 9083054 A role for the Saccharomyces cerevisiae ATX1 gene in copper trafficking and iron transport. 1997 Apr 4 1
35 9207117 hCTR1: a human gene for copper uptake identified by complementation in yeast. 1997 Jul 8 2
36 9325307 Restriction of copper export in Saccharomyces cerevisiae to a late Golgi or post-Golgi compartment in the secretory pathway. 1997 Oct 10 5
37 9346482 Metal ion chaperone function of the soluble Cu(I) receptor Atx1. 1997 Oct 31 1
38 9354393 Caenorhabditis elegans cDNA for a Menkes/Wilson disease gene homologue and its function in a yeast CCC2 gene deletion mutant. 1997 Jun 1