isospaglumic acid

folate hydrolase 1 ; Mus musculus







19 Article(s)
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Pub. Year
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1 34976589 Dendrimer-2PMPA selectively blocks upregulated microglial GCPII activity and improves cognition in a mouse model of multiple sclerosis. 2022 7
2 33638175 Mice deficient in the NAAG synthetase II gene Rimkla are impaired in a novel object recognition task. 2021 Jun 4
3 31730793 N-acetylaspartylglutamate (NAAG) and glutamate carboxypeptidase II: An abundant peptide neurotransmitter-enzyme system with multiple clinical applications. 2020 Jan 1
4 30883361 The NAAG'ing Concerns of Modeling Human Alzheimer's Disease in Mice. 2019 6
5 28285415 NAAG Peptidase Inhibitors Act via mGluR3: Animal Models of Memory, Alzheimer's, and Ethanol Intoxication. 2017 Sep 6
6 29020418 Striatal N-Acetylaspartate Synthetase Shati/Nat8l Regulates Depression-Like Behaviors via mGluR3-Mediated Serotonergic Suppression in Mice. 2017 Dec 1 1
7 27091009 Glutamate carboxypeptidase II gene knockout attenuates oxidative stress and cortical apoptosis after traumatic brain injury. 2016 Apr 18 2
8 25872793 Mice lacking glutamate carboxypeptidase II develop normally, but are less susceptible to traumatic brain injury. 2015 Jul 2
9 23200894 NAAG peptidase inhibitors and deletion of NAAG peptidase gene enhance memory in novel object recognition test. 2013 Feb 15 2
10 22850437 NAAG peptidase inhibitors block cognitive deficit induced by MK-801 and motor activation induced by d-amphetamine in animal models of schizophrenia. 2012 Jul 31 4
11 20865248 Discordant behavioral effects of psychotomimetic drugs in mice with altered NMDA receptor function. 2011 Jan 1
12 21093418 Orally active glutamate carboxypeptidase II inhibitor 2-MPPA attenuates dizocilpine-induced prepulse inhibition deficits in mice. 2011 Jan 31 4
13 21908619 Molecular identification of β-citrylglutamate hydrolase as glutamate carboxypeptidase 3. 2011 Nov 4 2
14 20624932 Glutamate carboxypeptidase II: an amyloid peptide-degrading enzyme with physiological function in the brain. 2010 Nov 2
15 19347959 Phenotypic characterization of mice heterozygous for a null mutation of glutamate carboxypeptidase II. 2009 Aug 2
16 16190866 Mice lacking glutamate carboxypeptidase II are protected from peripheral neuropathy and ischemic brain injury. 2005 Oct 2
17 15246864 Aspartoacylase deficiency does not affect N-acetylaspartylglutamate level or glutamate carboxypeptidase II activity in the knockout mouse brain. 2004 Aug 6 2
18 14556233 Early embryonic death of glutamate carboxypeptidase II (NAALADase) homozygous mutants. 2003 Dec 15 2
19 12358725 Deletion of the glutamate carboxypeptidase II gene in mice reveals a second enzyme activity that hydrolyzes N-acetylaspartylglutamate. 2002 Oct 1