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29868002 | IL-4 and IL-13 Receptor Signaling From 4PS to Insulin Receptor Substrate 2: There and Back Again, a Historical View. | 2018 |
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29870712 | A hispanolone-derived diterpenoid inhibits M2-Macrophage polarization in vitro via JAK/STAT and attenuates chitin induced inflammation in vivo. | 2018 Aug |
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| 3 |
29203888 | Insight into the molecular recognition mechanism of the coactivator NCoA1 by STAT6. | 2017 Dec 4 |
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| 4 |
27507812 | Suppressor of Cytokine Signaling (SOCS)1 Regulates Interleukin-4 (IL-4)-activated Insulin Receptor Substrate (IRS)-2 Tyrosine Phosphorylation in Monocytes and Macrophages via the Proteasome. | 2016 Sep 23 |
2 |
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27742835 | The TORC1-activated Proteins, p70S6K and GRB10, Regulate IL-4 Signaling and M2 Macrophage Polarization by Modulating Phosphorylation of Insulin Receptor Substrate-2. | 2016 Nov 25 |
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25369937 | Signaling pathways activated by a protease allergen in basophils. | 2014 Nov 18 |
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23562473 | IRS1 is highly expressed in localized breast tumors and regulates the sensitivity of breast cancer cells to chemotherapy, while IRS2 is highly expressed in invasive breast tumors. | 2013 Sep 28 |
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| 8 |
22217933 | STAT6 phosphorylation inhibitors block eotaxin-3 secretion in bronchial epithelial cells. | 2012 Jan 15 |
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| 9 |
22406175 | STAT6 and JAK1 are essential for IL-4-mediated suppression of prostaglandin production in human follicular dendritic cells: opposing roles of phosphorylated and unphosphorylated STAT6. | 2012 Apr |
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| 10 |
21106524 | PTB-associated splicing factor (PSF) functions as a repressor of STAT6-mediated Ig epsilon gene transcription by recruitment of HDAC1. | 2011 Feb 4 |
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| 11 |
21277633 | IL-4 and IL-13 suppress prostaglandins production in human follicular dendritic cells by repressing COX-2 and mPGES-1 expression through JAK1 and STAT6. | 2011 Mar |
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| 12 |
20610477 | Expression of the interleukin-4 receptor alpha in human conjunctival epithelial cells. | 2010 Sep |
2 |
| 13 |
19009233 | The fungal secondary metabolite trichodimerol inhibits TGF-β dependent cellular effects and tube formation of MDA-MB-231 cells. | 2009 Dec |
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| 14 |
19531027 | Human and rodent pancreatic beta-cells express IL-4 receptors and IL-4 protects against beta-cell apoptosis by activation of the PI3K and JAK/STAT pathways. | 2009 Dec 15 |
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| 15 |
19592641 | An atopy-associated polymorphism in the ectodomain of the IL-4R(alpha) chain (V50) regulates the persistence of STAT6 phosphorylation. | 2009 Aug 1 |
2 |
| 16 |
18005266 | Investigation of the interleukin (IL)-4/IL-4 receptor system in promyelocytic leukaemia PLB-985 cells during differentiation toward neutrophil-like phenotype: mechanism involved in IL-4-induced SOCS3 protein expression. | 2008 Jan |
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| 17 |
18653993 | Oxacyclododecindione, a novel inhibitor of IL-4 signaling from Exserohilum rostratum. | 2008 May |
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| 18 |
19109239 | Type I IL-4Rs selectively activate IRS-2 to induce target gene expression in macrophages. | 2008 Dec 23 |
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| 19 |
16762027 | Interleukin-4 supports interleukin-12-induced proliferation and interferon-gamma secretion in human activated lymphoblasts and T helper type 1 cells. | 2006 Sep |
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15699483 | LFA-1 co-stimulation inhibits T(h)2 differentiation by down-modulating IL-4 responsiveness. | 2005 Mar |
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| 21 |
15714203 | Interleukin-4 enhances proliferation of human pancreatic cancer cells: evidence for autocrine and paracrine actions. | 2005 Mar 14 |
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| 22 |
15817683 | Impaired interferon-gamma production as a consequence of STAT4 deficiency after autologous hematopoietic stem cell transplantation for lymphoma. | 2005 Aug 1 |
1 |
| 23 |
16181056 | Serine phosphorylation of Stat6 negatively controls its DNA-binding function. | 2005 Sep |
2 |
| 24 |
16210622 | Sequence motifs in IL-4R alpha mediating cell-cycle progression of primary lymphocytes. | 2005 Oct 15 |
1 |
| 25 |
14693161 | Interleukin-4 inhibits platelet-derived growth factor-induced preadipocyte proliferation. | 2004 Jan 21 |
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| 26 |
15123681 | Insulin receptor substrate-2-dependent interleukin-4 signaling in macrophages is impaired in two models of type 2 diabetes mellitus. | 2004 Jul 2 |
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| 27 |
12459556 | Regulation of the dephosphorylation of Stat6. Participation of Tyr-713 in the interleukin-4 receptor alpha, the tyrosine phosphatase SHP-1, and the proteasome. | 2003 Feb 7 |
4 |
| 28 |
12902491 | New programming of IL-4 receptor signal transduction in activated T cells: Stat6 induction and Th2 differentiation mediated by IL-4Ralpha lacking cytoplasmic tyrosines. | 2003 Aug 15 |
2 |
| 29 |
14530343 | Phosphatidylcholine-specific phospholipase C activity is necessary for the activation of STAT6. | 2003 Oct 15 |
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| 30 |
11773030 | Characterization of the interleukin-4 receptor complex in human corneal fibroblasts. | 2002 Jan |
2 |
| 31 |
11823524 | IL-4 up-regulates the expression of tissue inhibitor of metalloproteinase-2 in dermal fibroblasts via the p38 mitogen-activated protein kinase dependent pathway. | 2002 Feb 15 |
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| 32 |
11997017 | Corticosteroid inhibits IL-4 signaling through down-regulation of IL-4 receptor and STAT6 activity. | 2002 May 8 |
1 |
| 33 |
12115740 | Primary human articular chondrocytes, dedifferentiated chondrocytes, and synoviocytes exhibit differential responsiveness to interleukin-4: correlation with the expression pattern of the common receptor gamma chain. | 2002 Jul |
2 |
| 34 |
12138096 | An LXXLL motif in the transactivation domain of STAT6 mediates recruitment of NCoA-1/SRC-1. | 2002 Sep 27 |
2 |
| 35 |
12356680 | Molecular basis of the synergistic production of IL-1 receptor antagonist by human neutrophils stimulated with IL-4 and IL-10. | 2002 Oct |
1 |
| 36 |
11162477 | Identification of an inhibitor for interleukin 4-induced epsilon germline transcription and antigen-specific IgE production in vivo. | 2001 Jan 12 |
2 |
| 37 |
11574547 | Transcriptional activation by STAT6 requires the direct interaction with NCoA-1. | 2001 Dec 7 |
3 |
| 38 |
11714801 | The association of Aiolos transcription factor and Bcl-xL is involved in the control of apoptosis. | 2001 Dec 1 |
1 |
| 39 |
11714803 | Immunoreceptor tyrosine-based inhibitory motif of the IL-4 receptor associates with SH2-containing phosphatases and regulates IL-4-induced proliferation. | 2001 Dec 1 |
1 |
| 40 |
10627454 | Interleukin-4-induced transcriptional activation by stat6 involves multiple serine/threonine kinase pathways and serine phosphorylation of stat6. | 2000 Jan 15 |
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| 41 |
10631093 | Interleukin-4 mediates STAT6 activation in 3T3-L1 preadipocytes but not adipocytes. | 2000 Jan 19 |
4 |
| 42 |
10652211 | Possible involvement of Shc in IL-4-induced germline epsilon transcription in a human B cell line. | 2000 Feb 5 |
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| 43 |
10734320 | IL-4 regulation of IL-6 production involves Rac/Cdc42- and p38 MAPK-dependent pathways in keratinocytes. | 2000 Mar 16 |
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| 44 |
10845915 | Selective disruption of interleukin 4 autocrine-regulated loop by a tyrosine kinase inhibitor restricts activity of T-helper 2 cells. | 2000 Jun 15 |
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| 45 |
10875931 | Positive regulation of interleukin-4-mediated proliferation by the SH2-containing inositol-5'-phosphatase. | 2000 Sep 22 |
2 |
| 46 |
11101004 | The induction of the human hepatic CYP2E1 gene by interleukin 4 is transcriptional and regulated by protein kinase C. | 2000 |
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| 47 |
9923452 | Distinct actions of interleukin-9 and interleukin-4 on a hematopoietic stem cell line, EMLC1. | 1999 Jan |
3 |
| 48 |
9973378 | IL-4 selectively inhibits IL-2-triggered Stat5 activation, but not proliferation, in human T cells. | 1999 Feb 1 |
1 |
| 49 |
10080532 | Inhibition of IL-4-inducible gene expression in human monocytes by type I and type II interferons. | 1999 Mar |
1 |
| 50 |
10201928 | Repression of IL-4-induced gene expression by IFN-gamma requires Stat1 activation. | 1999 Apr 1 |
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