Arginine

arginase 1 ; Homo sapiens







105 Article(s)
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1 34599427 Arginase-1 Released into CSF After Aneurysmal Subarachnoid Hemorrhage Decreases Arginine/Ornithine Ratio: a Novel Prognostic Biomarker. 2022 Jun 4
2 35022194 Interrupting the nitrosative stress fuels tumor-specific cytotoxic T lymphocytes in pancreatic cancer. 2022 Jan 1
3 35203413 L-Arginine Depletion Improves Spinal Cord Injury via Immunomodulation and Nitric Oxide Reduction. 2022 Jan 18 1
4 35281666 Clinical status, biochemical profile and management of a single cohort of patients with arginase deficiency. 2022 Mar 1
5 35316752 Arginase: An emerging and promising therapeutic target for cancer treatment. 2022 May 2
6 33025106 Increased immunosuppression impairs tissue homeostasis with aging and age-related diseases. 2021 Jan 2
7 33232463 Single Nucleotide Polymorphisms in the Arginase 1 and 2 Genes Are Differentially Associated with Circulating l-Arginine Concentration in Unsupplemented and l-Arginine-Supplemented Adults. 2021 Apr 8 22
8 33410970 Arginase II polymorphisms modify the hypotensive responses to propofol by affecting nitric oxide bioavailability. 2021 Jun 1
9 33500272 Arginase Therapy Combines Effectively with Immune Checkpoint Blockade or Agonist Anti-OX40 Immunotherapy to Control Tumor Growth. 2021 Apr 2
10 33524560 An injectable hydrogel using an immunomodulating gelator for amplified tumor immunotherapy by blocking the arginase pathway. 2021 Apr 1 2
11 33754845 Development of a Novel Label-Free and High-Throughput Arginase-1 Assay Using Self-Assembled Monolayer Desorption Ionization Mass Spectrometry. 2021 Jul 1
12 34131176 Neutrophils drive endoplasmic reticulum stress-mediated apoptosis in cancer cells through arginase-1 release. 2021 Jun 15 1
13 34287772 Safety, PK/PD and preliminary anti-tumor activities of pegylated recombinant human arginase 1 (BCT-100) in patients with advanced arginine auxotrophic tumors. 2021 Dec 1
14 34326456 Cryo-EM structures of inhibitory antibodies complexed with arginase 1 provide insight into mechanism of action. 2021 Jul 29 2
15 34367736 Inhibition of arginase modulates T-cell response in the tumor microenvironment of lung carcinoma. 2021 1
16 34943588 Large-Scale Tissue Microarray Evaluation Corroborates High Specificity of High-Level Arginase-1 Immunostaining for Hepatocellular Carcinoma. 2021 Dec 14 1
17 32312763 Differential Regulation of l-Arginine Metabolism through Arginase 1 during Infection with Leishmania mexicana Isolates Obtained from Patients with Localized and Diffuse Cutaneous Leishmaniasis. 2020 Jun 22 5
18 32418491 High-Throughput Fluorescence-Based Activity Assay for Arginase-1. 2020 Oct 1
19 32647818 Structural insights into human Arginase-1 pH dependence and its inhibition by the small molecule inhibitor CB-1158. 2020 1
20 32721242 Common Variants in the ARG1 Gene Contribute to the Risk of Dilated Cardiomyopathy in the Han Chinese Population. 2020 Sep 1
21 32780724 Autophagic adaptation to oxidative stress alters peritoneal residential macrophage survival and ovarian cancer metastasis. 2020 Sep 17 1
22 32839531 Integrated proteomics and metabolomics reveals the comprehensive characterization of antitumor mechanism underlying Shikonin on colon cancer patient-derived xenograft model. 2020 Aug 24 1
23 32920160 Analysis of Cyclooxygenase 2, Programmed Cell Death Ligand 1, and Arginase 1 Expression in Human Pituitary Adenoma. 2020 Dec 1
24 33092030 Accumulation of 8-hydroxydeoxyguanosine, L-arginine and Glucose Metabolites by Liver Tumor Cells Are the Important Characteristic Features of Metabolic Syndrome and Non-Alcoholic Steatohepatitis-Associated Hepatocarcinogenesis. 2020 Oct 20 2
25 33128544 ARG1 functions as a tumor suppressor in breast cancer. 2020 Dec 11 1
26 30605863 Metabolic pathways of L-arginine and therapeutic consequences in tumors. 2019 Mar 2
27 30696923 Immune control by amino acid catabolism during tumorigenesis and therapy. 2019 Mar 2
28 30797943 Amino acid metabolism as drug target in autoimmune diseases. 2019 Apr 2
29 30808864 Endogenous arginase 2 as a potential biomarker for PEGylated arginase 1 treatment in xenograft models of squamous cell lung carcinoma. 2019 Feb 26 5
30 30890279 Overexpression of Arginase-1 is an indicator of poor prognosis in patients with colorectal cancer. 2019 Jun 2
31 31149961 Myeloid-Derived Suppressor Cells Mediate Immunosuppression After Cardiopulmonary Bypass. 2019 Aug 1
32 31177351 Nitric oxide production is downregulated during respiratory syncytial virus persistence by constitutive expression of arginase 1. 2019 Sep 1
33 31399282 Slc6a8-Mediated Creatine Uptake and Accumulation Reprogram Macrophage Polarization via Regulating Cytokine Responses. 2019 Aug 20 1
34 31646104 Extracellular vesicles released by ovarian carcinoma contain arginase 1 that mitigates antitumor immune response. 2019 2
35 31690955 Arginase-1-based vaccination against the tumor microenvironment: the identification of an optimal T-cell epitope. 2019 Nov 2
36 28374859 Influence of arginase polymorphisms and arginase levels/activity on the response to erectile dysfunction therapy with sildenafil. 2018 Apr 2
37 29227812 Overexpression of Arginase 1 is linked to DNMT3A and TET2 mutations in lower-grade myelodysplastic syndromes and chronic myelomonocytic leukemia. 2018 Feb 1
38 29399404 Frequent adaptive immune responses against arginase-1. 2018 1
39 29487337 Homoarginine and inhibition of human arginase activity: kinetic characterization and biological relevance. 2018 Feb 27 1
40 29559907 Use of Eflornithine (DFMO) in the Treatment of Early Alzheimer's Disease: A Compassionate Use, Single-Case Study. 2018 2
41 30228936 Spontaneous T-cell responses against Arginase-1 in the chronic myeloproliferative neoplasms relative to disease stage and type of driver mutation. 2018 1
42 27903651 T Cells Encountering Myeloid Cells Programmed for Amino Acid-dependent Immunosuppression Use Rictor/mTORC2 Protein for Proliferative Checkpoint Decisions. 2017 Jan 6 1
43 28071686 Identification of temporal genes involved in the mechanisms of spinal cord injury. 2017 Apr 1
44 28119468 Candida albicans Chitin Increases Arginase-1 Activity in Human Macrophages, with an Impact on Macrophage Antimicrobial Functions. 2017 Jan 24 1
45 28166447 Nutrition Support for Persistent Inflammation, Immunosuppression, and Catabolism Syndrome. 2017 Apr 1
46 28214225 A Relay Pathway between Arginine and Tryptophan Metabolism Confers Immunosuppressive Properties on Dendritic Cells. 2017 Feb 21 2
47 28315470 The nitric oxide synthase 2 pathway is targeted by both pro- and anti-inflammatory treatments in the immature human intestine. 2017 Jun 1 1
48 28545736 Amino-acid sensing and degrading pathways in immune regulation. 2017 Jun 2
49 29055959 Impaired Arginine Metabolism Coupled to a Defective Redox Conduit Contributes to Low Plasma Nitric Oxide in Polycystic Ovary Syndrome. 2017 1
50 29110610 VEGFR1 Signaling Regulates IL-4-Mediated Arginase 1 Expression in Macrophages. 2017 Dec 7 2