Dihydrotestosterone

UDP glucuronosyltransferase family 2 member B15 ; Homo sapiens







26 Article(s)
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1 35504423 Naftopidil enantiomers suppress androgen accumulation and induce cell apoptosis via the UDP-glucuronosyltransferase 2B15 in benign prostate hyperplasia. 2022 Jul 1
2 33549631 Potent inhibition of tributyltin (TBT) and triphenyltin (TPT) against multiple UDP-glucuronosyltransferases (UGT): A new potential mechanism underlying endocrine disrupting actions. 2021 Mar 1
3 34541032 Scaffold attachment factor B1 regulates androgen degradation pathways in prostate cancer. 2021 2
4 30262668 Loss of dihydrotestosterone-inactivation activity promotes prostate cancer castration resistance detectable by functional imaging. 2018 Nov 16 2
5 28881775 Uridine diphosphate-glucuronosyltransferase 2B15 D85Y gene polymorphism is associated with lower prostate cancer risk: a systematic review and meta-analysis. 2017 Aug 8 6
6 26797685 Classical and Non-Classical Roles for Pre-Receptor Control of DHT Metabolism in Prostate Cancer Progression. 2016 Apr 2
7 26163549 Regulation of Human UGT2B15 and UGT2B17 by miR-376c in Prostate Cancer Cell Lines. 2015 Sep 1
8 22532564 Protein kinase Cα and Src kinase support human prostate-distributed dihydrotestosterone-metabolizing UDP-glucuronosyltransferase 2B15 activity. 2012 Jul 13 1
9 21541968 Correlation between circulatory, local prostatic, and intra-prostatic androgen levels. 2011 Jun 15 1
10 19218247 Human cytosolic hydroxysteroid dehydrogenases of the aldo-ketoreductase superfamily catalyze reduction of conjugated steroids: implications for phase I and phase II steroid hormone metabolism. 2009 Apr 10 1
11 18302198 Androgen receptor mediates the expression of UDP-glucuronosyltransferase 2 B15 and B17 genes. 2008 Jun 1 2
12 18467088 Inactivation by UDP-glucuronosyltransferase enzymes: the end of androgen signaling. 2008 Apr 1
13 18471784 Inactivation of androgens by UDP-glucuronosyltransferases in the human prostate. 2008 Apr 1
14 17848572 UDP-glucuronosyltransferase 2B15 (UGT2B15) and UGT2B17 enzymes are major determinants of the androgen response in prostate cancer LNCaP cells. 2007 Nov 16 4
15 16595710 Human UDP-glucuronosyltransferase, UGT1A8, glucuronidates dihydrotestosterone to a monoglucuronide and further to a structurally novel diglucuronide. 2006 Jul 1
16 16690804 Estrogen regulation of the glucuronidation enzyme UGT2B15 in estrogen receptor-positive breast cancer cells. 2006 Aug 1
17 15065092 Prostate cancer and polymorphism D85Y in gene for dihydrotestosterone degrading enzyme UGT2B15: Frequency of DD homozygotes increases with Gleason Score. 2004 Jun 1 1
18 15126881 Asp85tyr polymorphism in the udp-glucuronosyltransferase (UGT) 2B15 gene and the risk of prostate cancer. 2004 Jun 3
19 15666817 Cellular specific expression of the androgen-conjugating enzymes UGT2B15 and UGT2B17 in the human prostate epithelium. 2004 Nov 1
20 11159850 Relative enzymatic activity, protein stability, and tissue distribution of human steroid-metabolizing UGT2B subfamily members. 2001 Feb 1
21 11129427 An allele-specific polymerase chain reaction method for the determination of the D85Y polymorphism in the human UDP-glucuronosyltransferase 2B15 gene in a case-control study of prostate cancer. 2000 Dec 4
22 10339403 Alteration of human UDP-glucuronosyltransferase UGT2B17 regio-specificity by a single amino acid substitution. 1999 May 28 1
23 9569009 Effect of fibroblastic growth factors (FGF) on steroid UDP-glucuronosyltransferase expression and activity in the LNCaP cell line. 1998 Jan 2
24 9699884 Characterization and regulation of UDP-glucuronosyltransferases in steroid target tissues. 1998 Apr 1
25 9202245 Differential regulation of two uridine diphospho-glucuronosyltransferases, UGT2B15 and UGT2B17, in human prostate LNCaP cells. 1997 Jul 1
26 8399210 Characterization of a cloned human dihydrotestosterone/androstanediol UDP-glucuronosyltransferase and its comparison to other steroid isoforms. 1993 Oct 12 1