| 1 |
26961407 | Protein Kinase C-α is a Critical Protein for Antisense Oligonucleotide-mediated Silencing in Mammalian Cells. | 2016 Jun |
1 |
| 2 |
27706607 | Effects of sodium lactate Ringer's injection on transfection of human protein kinase C-α antisense oligonucleotide in A549 lung cancer cells. | 2016 Aug 26 |
1 |
| 3 |
22801596 | Antisense to protein kinase C-alpha and p47phox attenuates the pro-inflammatory effects of human C-reactive protein in macrophages of biobreeding diabetic rats. | 2012 Oct |
1 |
| 4 |
19726358 | [Antisense oligonucleotides targeting protein kinase C alpha inhibits the proliferation of A549 cells]. | 2009 Jun |
3 |
| 5 |
17486587 | Reduction of PKC alpha decreases cell proliferation, migration, and invasion of human malignant hepatocellular carcinoma. | 2008 Jan 1 |
2 |
| 6 |
18463227 | Regulation of H(2)O(2)-induced necrosis by PKC and AMP-activated kinase signaling in primary cultured hepatocytes. | 2008 Jul |
1 |
| 7 |
19077250 | Protein kinase Cepsilon is important for migration of neuroblastoma cells. | 2008 Dec 11 |
1 |
| 8 |
16297876 | PKCalpha expression regulated by Elk-1 and MZF-1 in human HCC cells. | 2006 Jan 6 |
2 |
| 9 |
16387524 | Involvement of mu- and m-calpains and protein kinase C isoforms in L8 myoblast differentiation. | 2006 |
1 |
| 10 |
16424642 | The role of protein kinase C-alpha in hematologic malignancies. | 2006 |
1 |
| 11 |
16854530 | Protein kinase Cbeta isoform down-regulates the expression of MDR3 P-glycoprotein in human Chang liver cells. | 2006 Oct |
3 |
| 12 |
15447940 | Distinct PKC isoforms mediate cell survival and DNA synthesis in thrombin-induced myofibroblasts. | 2005 Jan |
2 |
| 13 |
15701280 | Efficacy and toxicity of the antisense oligonucleotide aprinocarsen directed against protein kinase C-alpha delivered as a 21-day continuous intravenous infusion in patients with recurrent high-grade astrocytomas. | 2005 Jan |
2 |
| 14 |
15721302 | Phorbol ester phorbol-12-myristate-13-acetate promotes anchorage-independent growth and survival of melanomas through MEK-independent activation of ERK1/2. | 2005 Apr 1 |
3 |
| 15 |
15730925 | Effects of antisense oligonucleotides of PKC-alpha on proliferation and apoptosis of HepG2 in vitro. | 2005 Feb |
1 |
| 16 |
15764646 | Lysophosphatidylcholine increases endothelial permeability: role of PKCalpha and RhoA cross talk. | 2005 Aug |
1 |
| 17 |
14687784 | The role of protein kinase C-alpha (PKC-alpha) in malignancies of the gastrointestinal tract. | 2004 Jan |
1 |
| 18 |
15057036 | The role of protein kinase C-alpha (PKC-alpha) in melanoma. | 2004 Apr |
1 |
| 19 |
12652652 | Role of protein kinase C alpha in calcium induced keratinocyte differentiation: defective regulation in squamous cell carcinoma. | 2003 May |
4 |
| 20 |
12917261 | Protein kinase Cbeta1, a major regulator of TCR-CD28-activated signal transduction leading to IL-2 gene transcription and secretion. | 2003 Sep |
1 |
| 21 |
12917818 | Antisense strategies targeting protein kinase C: preclinical and clinical development. | 2003 Aug |
2 |
| 22 |
11751262 | Protein kinase Calpha is required for endothelin-1-induced proliferation of human myometrial cells. | 2002 Jan |
3 |
| 23 |
11909826 | Inhibition of protein kinase Calpha prevents endothelial cell migration and vascular tube formation in vitro and myocardial neovascularization in vivo. | 2002 Mar 22 |
4 |
| 24 |
11952172 | Protein kinase Calpha is a calpain target in cultured embryonic muscle cells. | 2002 Feb |
1 |
| 25 |
12149272 | Regulation of lipoprotein lipase by protein kinase C alpha in 3T3-F442A adipocytes. | 2002 Oct 11 |
2 |
| 26 |
12415618 | Modulation of multidrug resistance in human ovarian cancer cell lines by inhibition of P-glycoprotein 170 and PKC isoenzymes with antisense oligonucleotides. | 2002 Jan-Feb |
1 |
| 27 |
12435817 | Identification of PKCalpha isoform-specific effects in cardiac myocytes using antisense phosphorothioate oligonucleotides. | 2002 Dec |
3 |
| 28 |
11451996 | High PKC alpha and low E-cadherin expression contribute to high migratory activity of colon carcinoma cells. | 2001 Jul |
1 |
| 29 |
11513935 | Antisense therapy in oncology: new hope for an old idea? | 2001 Aug 11 |
2 |
| 30 |
11516649 | Crosstalk between ARF6 and protein kinase Calpha in Fc(gamma)RI-mediated activation of phospholipase D1. | 2001 Jun 5 |
1 |
| 31 |
10938109 | Insulin-activated protein kinase Cbeta bypasses Ras and stimulates mitogen-activated protein kinase activity and cell proliferation in muscle cells. | 2000 Sep |
1 |
| 32 |
9880552 | Characterization of a potent and specific class of antisense oligonucleotide inhibitor of human protein kinase C-alpha expression. | 1999 Jan 15 |
2 |
| 33 |
9927633 | Induction of p53-dependent, insulin-like growth factor-binding protein-3-mediated apoptosis in glioblastoma multiforme cells by a protein kinase Calpha antisense oligonucleotide. | 1999 Feb |
4 |
| 34 |
10354503 | Protein kinase C alpha protein expression is necessary for sustained erythropoietin production in human hepatocellular carcinoma (Hep3B) cells exposed to hypoxia. | 1999 Jun 8 |
1 |
| 35 |
10530711 | Antisense therapy of hematologic malignancies. | 1999 Oct |
2 |
| 36 |
10589745 | Phase I study of an antisense oligonucleotide to protein kinase C-alpha (ISIS 3521/CGP 64128A) in patients with cancer. | 1999 Nov |
1 |
| 37 |
10628339 | The involvement of protein kinase C isoenzymes alpha, epsilon and zeta in the sensitivity to antitumor treatment and apoptosis induction. | 1999 Sep-Oct |
3 |
| 38 |
11713804 | Technology evaluation: ISIS-3521. | 1999 Jun |
1 |
| 39 |
9474241 | Antitumor activity of a PKC-alpha antisense oligonucleotide in combination with standard chemotherapeutic agents against various human tumors transplanted into nude mice. | 1998 Jan |
1 |
| 40 |
9499434 | Differential role for protein kinase C-mediated signaling in the proliferation of medulloblastoma cell lines. | 1998 Apr |
2 |
| 41 |
9506361 | Differential induction of cell death in human glioma cell lines by sodium nitroprusside. | 1998 Mar 15 |
1 |
| 42 |
9514882 | A role for protein kinase C alpha in stimulation of prostaglandin G/H synthase-2 transcription by 14,15-epoxyeicosatrienoic acid. | 1998 Mar 6 |
1 |
| 43 |
9665591 | Apoptosis is induced in glioma cells by antisense oligonucleotides to protein kinase C alpha and is enhanced by cycloheximide. | 1998 Jun 1 |
1 |
| 44 |
9677384 | Antisense oligonucleotides targeted against protein kinase Cbeta and CbetaII block 1,25-(OH)2D3-induced differentiation. | 1998 Jul 31 |
1 |
| 45 |
9706141 | Directed antisense therapy confirms the role of protein kinase C-alpha in the tumorigenicity of pancreatic cancer. | 1998 Aug |
2 |
| 46 |
9924975 | Effect of polyisobutylcyanoacrylate nanoparticles and lipofectin loaded with oligonucleotides on cell viability and PKC alpha neosynthesis in HepG2 cells. | 1998 Dec |
4 |
| 47 |
9203625 | Antisense oligonucleotides targeting human protein kinase C-alpha inhibit phorbol ester-induced reduction of bradykinin-evoked calcium mobilization in A549 cells. | 1997 Feb |
2 |
| 48 |
9236856 | Toxicological and pharmacokinetic properties of chemically modified antisense oligonucleotide inhibitors of PKC-alpha and C-raf kinase. | 1997 Jul |
1 |
| 49 |
9253654 | Phosphorylation events mediated by protein kinase C alpha and epsilon participate in regulation of tau steady-state levels and generation of certain "Alzheimer-like" phospho-epitopes. | 1997 Jun |
3 |
| 50 |
8758918 | Inhibition of growth of human tumor cell lines in nude mice by an antisense of oligonucleotide inhibitor of protein kinase C-alpha expression. | 1996 Aug 1 |
1 |