Testosterone

cytochrome P450, family 17, subfamily a, polypeptide 1 ; Rattus norvegicus







26 Article(s)
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Pub. Year
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1 35438966 Low Levels of Perfluorooctanoic Acid Exposure Activates Steroid Hormone Biosynthesis through Repressing Histone Methylation in Rats. 2022 May 3 1
2 35605789 In utero bisphenol AF exposure causes fetal Leydig cell dysfunction and induces multinucleated gonocytes by generating oxidative stress and reducing the SIRT1/PGC1α signals. 2022 Jul 15 1
3 34261222 Chronic low-level perfluorooctane sulfonate (PFOS) exposure promotes testicular steroidogenesis through enhanced histone acetylation. 2021 Sep 1 1
4 34601003 Stress-induced glucocorticoids alter the Leydig cells' timing and steroidogenesis-related systems. 2021 Dec 1 1
5 32084696 miR-142-5p/DAX1-dependent regulation of P450c17 contributes to triclosan-mediated testosterone suppression. 2020 May 15 3
6 32886530 Spermatogenesis and steroidogenesis disruption in a model of metabolic syndrome rats. 2020 Sep 4 1
7 28705778 Maternal linuron exposure alters testicular development in male offspring rats at the whole genome level. 2017 Aug 15 1
8 25623143 Differences in neonatal exposure to estradiol or testosterone on ovarian function and hormonal levels. 2015 Feb 1 1
9 25782017 Effects of local testicular heat treatment on Leydig cell hyperplasia and testosterone biosynthesis in rat testes. 2015 Mar 18 2
10 25995226 Prolonged exposure to acetaminophen reduces testosterone production by the human fetal testis in a xenograft model. 2015 May 20 1
11 26137611 [Testicular oxidative stress and downregulation of CYP17a1 indused by di (n-butyl) phthalate inhibit synthesis of testosterone]. 2015 May 1
12 23709086 Dysregulation of ovarian follicular development in female rat: LH decreases FSH sensitivity during preantral-early antral transition. 2013 Aug 1
13 21046364 Role of cytochrome P450c17α in dibromoacetic acid-induced testicular toxicity in rats. 2011 May 1
14 21427060 Pharmacological doses of testosterone upregulated androgen receptor and 3-Beta-hydroxysteroid dehydrogenase/delta-5-delta-4 isomerase and impaired leydig cells steroidogenesis in adult rats. 2011 Jun 2
15 19497980 Retinoic acid stimulates 17beta-estradiol and testosterone synthesis in rat hippocampal slice cultures. 2009 Sep 1
16 17369198 Sensitivity of fetal rat testicular steroidogenesis to maternal prochloraz exposure and the underlying mechanism of inhibition. 2007 Jun 1
17 11913545 Administration of estradiol-3-benzoate down-regulates the expression of testicular steroidogenic enzyme genes for testosterone production in the adult rat. 2002 Feb 1
18 9721064 Novel nonsteroidal inhibitor of cytochrome P450(17alpha) (17alpha-hydroxylase/C17-20 lyase), YM116, decreased prostatic weights by reducing serum concentrations of testosterone and adrenal androgens in rats. 1998 Sep 15 1
19 9029727 Regulation of androgen synthesis: the late steroidogenic pathway. 1997 Jan 1
20 9384514 The role of cyclic AMP production, calcium channel activation and enzyme activities in the inhibition of testosterone secretion by amphetamine. 1997 Nov 1
21 8603575 Expression of cytochrome P450 17alpha-hydroxylase/C17-20 lyase in the fetal rat testis is reduced by maternal exposure to exogenous estrogens. 1996 Mar 1
22 8957694 Are Leydig cell steroidogenic enzymes differentially regulated with aging? 1996 Sep-Oct 1
23 8980886 Splenic macrophages can modify steroidogenesis of Leydig cells. 1996 Oct 1
24 8525490 Lead affects steroidogenesis in rat Leydig cells in vivo and in vitro. 1995 Nov 20 2
25 8404681 Differential regulation of steroidogenic enzymes during differentiation optimizes testosterone production by adult rat Leydig cells. 1993 Nov 1
26 2031442 Regulation of testicular P-450 cholesterol side-chain cleavage and P-450 C17-20 lyase/C17 hydroxylase enzymes in the neonatal and adult rat. 1991 Apr 1