Dihydrotestosterone

hydroxy-delta-5-steroid dehydrogenase, 3 beta- and steroid delta-isomerase 1 ; Homo sapiens







21 Article(s)
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1 33141329 HSD3B1 variant and androgen-deprivation therapy outcome in prostate cancer. 2021 Jan 2
2 32053149 HSD3B1 Genotype and Clinical Outcomes in Metastatic Castration-Sensitive Prostate Cancer. 2020 Apr 1 1
3 32866512 Germline HSD3B1 Genetics and Prostate Cancer Outcomes. 2020 Nov 3
4 29049452 HSD3B1 and Response to a Nonsteroidal CYP17A1 Inhibitor in Castration-Resistant Prostate Cancer. 2018 Apr 1 1
5 29049492 Association of HSD3B1 Genotype With Response to Androgen-Deprivation Therapy for Biochemical Recurrence After Radiotherapy for Localized Prostate Cancer. 2018 Apr 1 1
6 29674118 Germline Variant in HSD3B1 (1245 A > C) and Response to Abiraterone Acetate Plus Prednisone in Men With New-Onset Metastatic Castration-Resistant Prostate Cancer. 2018 Aug 1
7 29939161 HSD3B1(1245A>C) variant regulates dueling abiraterone metabolite effects in prostate cancer. 2018 Aug 1 3
8 27139182 Human 3β-hydroxysteroid dehydrogenase type 1 in human breast cancer: clinical significance and prognostic associations. 2016 Jul 2
9 27561382 Dihydrotestosterone synthesis pathways from inactive androgen 5α-androstane-3β,17β-diol in prostate cancer cells: Inhibition of intratumoural 3β-hydroxysteroid dehydrogenase activities by abiraterone. 2016 Aug 26 3
10 27575027 HSD3B1 and resistance to androgen-deprivation therapy in prostate cancer: a retrospective, multicohort study. 2016 Oct 2
11 26030522 Conversion of abiraterone to D4A drives anti-tumour activity in prostate cancer. 2015 Jul 16 1
12 22753664 Abiraterone inhibits 3β-hydroxysteroid dehydrogenase: a rationale for increasing drug exposure in castration-resistant prostate cancer. 2012 Jul 1 2
13 17826523 Association between polymorphisms in HSD3B1 and UGT2B17 and prostate cancer risk. 2007 Aug 4
14 14672942 Human cytosolic 3alpha-hydroxysteroid dehydrogenases of the aldo-keto reductase superfamily display significant 3beta-hydroxysteroid dehydrogenase activity: implications for steroid hormone metabolism and action. 2004 Mar 12 1
15 15383625 Tibolone is metabolized by the 3alpha/3beta-hydroxysteroid dehydrogenase activities of the four human isozymes of the aldo-keto reductase 1C subfamily: inversion of stereospecificity with a delta5(10)-3-ketosteroid. 2004 Dec 1
16 15666817 Cellular specific expression of the androgen-conjugating enzymes UGT2B15 and UGT2B17 in the human prostate epithelium. 2004 Nov 4
17 14643063 Inactivation of androgens by UDP-glucuronosyltransferase enzymes in humans. 2003 Dec 4
18 10487690 Metabolism of dihydrotestosterone in human liver: importance of 3alpha- and 3beta-hydroxysteroid dehydrogenase. 1999 Sep 8
19 8547174 Structure-function relationships and molecular genetics of the 3 beta-hydroxysteroid dehydrogenase gene family. 1995 Dec 1
20 1944309 Structure and expression of a new complementary DNA encoding the almost exclusive 3 beta-hydroxysteroid dehydrogenase/delta 5-delta 4-isomerase in human adrenals and gonads. 1991 Aug 1
21 3165109 delta 5-3 beta-hydroxysteroid dehydrogenase activity in sebaceous glands of scalp in male-pattern baldness. 1988 Aug 1