| 1 |
35421371 | VAP-A and its binding partner CERT drive biogenesis of RNA-containing extracellular vesicles at ER membrane contact sites. | 2022 Apr 25 |
1 |
| 2 |
33507882 | Epithelial IL-33 appropriates exosome trafficking for secretion in chronic airway disease. | 2021 Feb 22 |
2 |
| 3 |
33583073 | The doxorubicin-induced cell motility network is under the control of the ceramide-activated protein phosphatase 1 alpha. | 2021 Mar |
2 |
| 4 |
33738905 | Neutral sphingomyelinase-2 and cardiometabolic diseases. | 2021 Aug |
3 |
| 5 |
34096319 | Aberrant sphingomyelin 31P-NMR signatures in giant cell tumour of bone. | 2021 Dec |
1 |
| 6 |
32082486 | Sphingomyelin phosphodiesterase 3 methylation and silencing in oral squamous cell carcinoma results in increased migration and invasion and altered stress response. | 2020 Feb 4 |
4 |
| 7 |
32298582 | Novel Human Neutral Sphingomyelinase 2 Inhibitors as Potential Therapeutics for Alzheimer's Disease. | 2020 Jun 11 |
2 |
| 8 |
32307766 | Ceramide launches an acute anti-adhesion pro-migration cell signaling program in response to chemotherapy. | 2020 Jun |
4 |
| 9 |
32466233 | DNA Damage Regulates Senescence-Associated Extracellular Vesicle Release via the Ceramide Pathway to Prevent Excessive Inflammatory Responses. | 2020 May 25 |
2 |
| 10 |
32998995 | β-Galactosylceramidase Promotes Melanoma Growth via Modulation of Ceramide Metabolism. | 2020 Nov 15 |
1 |
| 11 |
33008902 | Inhibition of neutral sphingomyelinase 2 promotes remyelination. | 2020 Oct |
1 |
| 12 |
33033337 | Neutral sphingomyelinase 2 regulates inflammatory responses in monocytes/macrophages induced by TNF-α. | 2020 Oct 8 |
1 |
| 13 |
33088808 | Neutral Sphingomyelinase-2 (NSM 2) Controls T Cell Metabolic Homeostasis and Reprogramming During Activation. | 2020 |
2 |
| 14 |
30889865 | Mechanism of Rapid Nuclear Factor-E2-Related Factor 2 (Nrf2) Activation via Membrane-Associated Estrogen Receptors: Roles of NADPH Oxidase 1, Neutral Sphingomyelinase 2 and Epidermal Growth Factor Receptor (EGFR). | 2019 Mar 18 |
1 |
| 15 |
30890560 | The juxtamembrane linker in neutral sphingomyelinase-2 functions as an intramolecular allosteric switch that activates the enzyme. | 2019 May 3 |
2 |
| 16 |
30921693 | Neutral sphingomyelinase 2 inhibitors based on the 4-(1H-imidazol-2-yl)-2,6-dialkoxyphenol scaffold. | 2019 May 15 |
2 |
| 17 |
31555088 | Inhibition of nSMase2 Reduces the Transfer of Oligomeric α-Synuclein Irrespective of Hypoxia. | 2019 |
2 |
| 18 |
31681760 | Role of Neutral Sphingomyelinase-2 (NSM 2) in the Control of T Cell Plasma Membrane Lipid Composition and Cholesterol Homeostasis. | 2019 |
2 |
| 19 |
29321137 | Novel function of ceramide for regulation of mitochondrial ATP release in astrocytes. | 2018 Mar |
3 |
| 20 |
29720981 | The Neutral Sphingomyelinase 2 Is Required to Polarize and Sustain T Cell Receptor Signaling. | 2018 |
1 |
| 21 |
29867196 | Activation of neutral sphingomyelinase 2 by starvation induces cell-protective autophagy via an increase in Golgi-localized ceramide. | 2018 Jun 4 |
4 |
| 22 |
28652336 | Structure of human nSMase2 reveals an interdomain allosteric activation mechanism for ceramide generation. | 2017 Jul 11 |
5 |
| 23 |
27013100 | ATRA transcriptionally induces nSMase2 through CBP/p300-mediated histone acetylation. | 2016 May |
2 |
| 24 |
27660431 | Neutral sphingomyelinase-2, acid sphingomyelinase, and ceramide levels in COPD patients compared to controls. | 2016 |
4 |
| 25 |
25347576 | Src regulates cigarette smoke-induced ceramide generation via neutral sphingomyelinase 2 in the airway epithelium. | 2015 Jun |
3 |
| 26 |
25394686 | Secretion of small/microRNAs including miR-638 into extracellular spaces by sphingomyelin phosphodiesterase 3. | 2015 Jan |
2 |
| 27 |
25465297 | Roles and regulation of neutral sphingomyelinase-2 in cellular and pathological processes. | 2015 Jan |
2 |
| 28 |
25555205 | Hyaluronan synthase-2 upregulation protects smpd3-deficient fibroblasts against cell death induced by nutrient deprivation, but not against apoptosis evoked by oxidized LDL. | 2015 |
1 |
| 29 |
25833198 | Guggulsterone and bexarotene induce secretion of exosome-associated breast cancer resistance protein and reduce doxorubicin resistance in MDA-MB-231 cells. | 2015 Oct 1 |
2 |
| 30 |
26010541 | Cambinol, a novel inhibitor of neutral sphingomyelinase 2 shows neuroprotective properties. | 2015 |
3 |
| 31 |
26070932 | The traditional Tibetan medicine Yukyung Karne exhibits a potent anti-metastatic activity by inhibiting the epithelial to mesenchymal transition and cell migration. | 2015 Jun 13 |
2 |
| 32 |
26512957 | P53-dependent upregulation of neutral sphingomyelinase-2: role in doxorubicin-induced growth arrest. | 2015 Oct 29 |
2 |
| 33 |
24684526 | Lung injury and lung cancer caused by cigarette smoke-induced oxidative stress: Molecular mechanisms and therapeutic opportunities involving the ceramide-generating machinery and epidermal growth factor receptor. | 2014 Nov 20 |
1 |
| 34 |
24694597 | Primary cilia in stem cells and neural progenitors are regulated by neutral sphingomyelinase 2 and ceramide. | 2014 Jun |
2 |
| 35 |
24747163 | Vam3, a resveratrol dimer, inhibits cigarette smoke-induced cell apoptosis in lungs by improving mitochondrial function. | 2014 Jun |
1 |
| 36 |
25240837 | Curcumin induces apoptosis of multidrug-resistant human leukemia HL60 cells by complex pathways leading to ceramide accumulation. | 2014 Dec |
3 |
| 37 |
25428807 | Exosome-mediated transfer of miR-10b promotes cell invasion in breast cancer. | 2014 Nov 26 |
3 |
| 38 |
25521388 | Neutral sphingomyelinase in physiological and measles virus induced T cell suppression. | 2014 Dec |
3 |
| 39 |
23563653 | Lung cancer and lung injury: the dual role of ceramide. | 2013 |
5 |
| 40 |
23651497 | A signaling cascade mediated by ceramide, src and PDGFRβ coordinates the activation of the redox-sensitive neutral sphingomyelinase-2 and sphingosine kinase-1. | 2013 Aug |
3 |
| 41 |
23889969 | Neutral sphingomyelinase 2 modulates cytotoxic effects of protopanaxadiol on different human cancer cells. | 2013 Jul 27 |
3 |
| 42 |
24183051 | [Advance in research on regulatory mechanism and functions of neutral sphingomyelinse 2]. | 2013 Oct |
2 |
| 43 |
22074919 | Neutral sphingomyelinase 2 activity and protein stability are modulated by phosphorylation of five conserved serines. | 2012 Jan 2 |
2 |
| 44 |
22258513 | Increased ceramide in brains with Alzheimer's and other neurodegenerative diseases. | 2012 |
1 |
| 45 |
22452947 | Off-target function of the Sonic hedgehog inhibitor cyclopamine in mediating apoptosis via nitric oxide-dependent neutral sphingomyelinase 2/ceramide induction. | 2012 May |
3 |
| 46 |
22532571 | Astrocytes secrete exosomes enriched with proapoptotic ceramide and prostate apoptosis response 4 (PAR-4): potential mechanism of apoptosis induction in Alzheimer disease (AD). | 2012 Jun 15 |
2 |
| 47 |
22899568 | Hyperosmolarity-induced lipid droplet formation depends on ceramide production by neutral sphingomyelinase 2. | 2012 Nov |
2 |
| 48 |
22974251 | Expression of ceramide-metabolising enzymes in subcutaneous and intra-abdominal human adipose tissue. | 2012 Sep 13 |
1 |
| 49 |
23046545 | Evidence for coordination of lysosomal (ASMase) and plasma membrane (NSMase2) forms of sphingomyelinase from mutant mice. | 2012 Nov 16 |
1 |
| 50 |
20448054 | Neutral sphingomyelinase 2: a novel target in cigarette smoke-induced apoptosis and lung injury. | 2011 Mar |
3 |