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epoxide hydrolase 2 ; Rattus norvegicus







30 Article(s)
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1 35303234 Soluble epoxide hydrolase inhibition avoid formalin-induced inflammatory hyperalgesia in the temporomandibular joint. 2022 Jun 2
2 35344709 Adeno-associated virus-mediated in vivo suppression of expression of EPHX2 gene modulates the activity of paraventricular nucleus neurons in spontaneously hypertensive rats. 2022 May 28 3
3 32767848 Soluble epoxide hydrolase inhibition improves cognitive function and parenchymal artery dilation in a hypertensive model of chronic cerebral hypoperfusion. 2021 Jan 2
4 34794001 Further exploration of the structure-activity relationship of dual soluble epoxide hydrolase/fatty acid amide hydrolase inhibitors. 2021 Dec 1 1
5 32736189 Peripheral soluble epoxide hydrolase inhibition reduces hypernociception and inflammation in albumin-induced arthritis in temporomandibular joint of rats. 2020 Oct 2
6 33475089 Inhibition of soluble epoxide hydrolase offers protection against fructose-induced diabetes and related metabolic complications in rats. 2020 Oct 1
7 30644034 TPPU, a sEH Inhibitor, Attenuates Corticosterone-Induced PC12 Cell Injury by Modulation of BDNF-TrkB Pathway. 2019 Mar 1
8 30728778 Pharmacological Blockade of Soluble Epoxide Hydrolase Attenuates the Progression of Congestive Heart Failure Combined With Chronic Kidney Disease: Insights From Studies With Fawn-Hooded Hypertensive Rats. 2019 2
9 29529602 Combined Inhibition of Soluble Epoxide Hydrolase and Renin-Angiotensin System Exhibits Superior Renoprotection to Renin-Angiotensin System Blockade in 5/6 Nephrectomized Ren-2 Transgenic Hypertensive Rats with Established Chronic Kidney Disease. 2018 2
10 28002622 Inhibition of soluble epoxide hydrolase augments astrocyte release of vascular endothelial growth factor and neuronal recovery after oxygen-glucose deprivation. 2017 Mar 2
11 28332266 11,12-Epoxyeicosatrienoic acid induces vasodilator response in the rat perfused mesenteric vasculature. 2017 Jan 2
12 28741242 The weakening effect of soluble epoxide hydrolase inhibitor AUDA on febrile response to lipopolysaccharide and turpentine in rat. 2017 Nov 1
13 28822809 Inhibition of soluble epoxide hydrolase lowers portal hypertension in cirrhotic rats by ameliorating endothelial dysfunction and liver fibrosis. 2017 Jul 3
14 28827137 A novel mechanism of ascorbate direct modulation of soluble epoxide hydrolase. 2017 Jul 4
15 25663200 Soluble epoxide hydrolase inhibition provides multi-target therapeutic effects in rats after spinal cord injury. 2016 Apr 2
16 26545915 Epoxyeicosanoid Signaling Provides Multi-target Protective Effects on Neurovascular Unit in Rats After Focal Ischemia. 2016 Feb 2
17 24471737 Inhibition of soluble epoxide hydrolase is renoprotective in 5/6 nephrectomized Ren-2 transgenic hypertensive rats. 2014 Mar 2
18 24530032 Structure-based optimization of cyclopropyl urea derivatives as potent soluble epoxide hydrolase inhibitors for potential decrease of renal injury without hypotensive action. 2014 Mar 1 1
19 23039246 Antihypertensive action of soluble epoxide hydrolase inhibition in Ren-2 transgenic rats is mediated by suppression of the intrarenal renin-angiotensin system. 2013 Apr 2
20 23307303 Antihypertensive and renoprotective actions of soluble epoxide hydrolase inhibition in ANG II-dependent malignant hypertension are abolished by pretreatment with L-NAME. 2013 Feb 1
21 23967089 Aging, estrogen loss and epoxyeicosatrienoic acids (EETs). 2013 2
22 22155000 A soluble epoxide hydrolase inhibitor--8-HUDE increases pulmonary vasoconstriction through inhibition of K(ATP) channels. 2012 Feb 2
23 22155238 Soluble epoxide hydrolase inhibition improves myocardial perfusion and function in experimental heart failure. 2012 Mar 2
24 21039415 Cardioprotective effect of a dual acting epoxyeicosatrienoic acid analogue towards ischaemia reperfusion injury. 2011 Feb 2
25 21843605 Differential effect of amyloid β on the cytochrome P450 epoxygenase activity in rat brain. 2011 Oct 27 2
26 19226702 Inhibition of the soluble epoxide hydrolase attenuates monocrotaline-induced pulmonary hypertension in rats. 2009 Feb 4
27 19285984 Epoxyeicosatrienoic acids limit damage to mitochondrial function following stress in cardiac cells. 2009 Jun 2
28 19304946 Epoxyeicosanoids as mediators of neurogenic vasodilation in cerebral vessels. 2009 May 2
29 17639071 A novel role for P450 eicosanoids in the neurogenic control of cerebral blood flow in the rat. 2007 Jul 2
30 7840649 Metabolism of epoxyeicosatrienoic acids by cytosolic epoxide hydrolase: substrate structural determinants of asymmetric catalysis. 1995 Jan 10 1