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32510630 | In vivo enrichment of genetically manipulated platelets for murine hemophilia B gene therapy. | 2021 Jan |
1 |
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19844954 | Effect of O6-chloroethylguanine DNA lesions on the kinetics and mechanism of micronucleus induction in vivo. | 2010 Apr |
3 |
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18076130 | Co-expression of MGMT(P140K) and alpha-L-iduronidase in primary hepatocytes from mucopolysaccharidosis type I mice enables efficient selection with metabolic correction. | 2008 Mar |
2 |
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17116724 | Role of O6-methylguanine-DNA methyltransferase in protecting from alkylating agent-induced toxicity and mutations in mice. | 2007 May |
2 |
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16927363 | Characterisation of a P140K mutant O6-methylguanine-DNA-methyltransferase (MGMT)-expressing transgenic mouse line with drug-selectable bone marrow. | 2006 Sep |
2 |
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16390267 | Hematopoietic stem cell transduction and amplification in large animal models. | 2005 Dec |
2 |
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15284838 | Hematopoietic stem cell gene therapy of murine protoporphyria by methylguanine-DNA-methyltransferase-mediated in vivo drug selection. | 2004 Nov |
1 |
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15308322 | Nuclear-localizing O6-benzylguanine-resistant GFP-MGMT fusion protein as a novel in vivo selection marker. | 2004 Aug |
1 |
| 9 |
12965075 | Drug selection of mutant methylguanine methyltransferase from different oncoretroviral backbones results in multilineage hematopoietic transgene expression in primary and secondary recipients. | 2003 Aug |
1 |
| 10 |
14506174 | Sensitization of pancreatic tumor xenografts to carmustine and temozolomide by inactivation of their O6-Methylguanine-DNA methyltransferase with O6-benzylguanine or O6-benzyl-2'-deoxyguanosine. | 2003 Sep 1 |
2 |
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14707273 | Hematopoietic expression of O(6)-methylguanine DNA methyltransferase-P140K allows intensive treatment of human glioma xenografts with combination O(6)-benzylguanine and 1,3-bis-(2-chloroethyl)-1-nitrosourea. | 2003 Dec |
7 |
| 12 |
12439597 | Toxicity of intracranial and intraperitoneal O6-benzyl guanine in combination with BCNU delivered locally in a mouse model. | 2002 Nov |
2 |
| 13 |
11553261 | Protection of hematopoietic cells from O(6)-alkylation damage by O(6)-methylguanine DNA methyltransferase gene transfer: studies with different O(6)-alkylating agents and retroviral backbones. | 2001 Jul |
1 |
| 14 |
10647505 | Potentiation of BCNU antitumor efficacy by 9-substituted O6-benzylguanines. Effect of metabolism. | 2000 |
3 |
| 15 |
10807772 | Limiting numbers of G156A O(6)-methylguanine-DNA methyltransferase-transduced marrow progenitors repopulate nonmyeloablated mice after drug selection. | 2000 May 15 |
1 |
| 16 |
10188873 | Influence of O6-benzylguanine on the anti-tumour activity and normal tissue toxicity of 1,3-bis(2-chloroethyl)-1-nitrosourea and molecular combinations of 5-fluorouracil and 2-chloroethyl-1-nitrosourea in mice. | 1999 Mar |
1 |
| 17 |
10375003 | DNA repair methyltransferase (Mgmt) knockout mice are sensitive to the lethal effects of chemotherapeutic alkylating agents. | 1999 May |
1 |
| 18 |
8993023 | Reversal of 1,3-bis(2-chloroethyl)-1-nitrosourea-induced severe immunodeficiency by transduction of murine long-lived hemopoietic progenitor cells using O6-methylguanine DNA methyltransferase complementary DNA. | 1997 Jan 15 |
3 |
| 19 |
9293904 | Human alkyltransferase-transduced murine myeloid progenitors are enriched in vivo by BCNU treatment of transplanted mice. | 1997 Sep |
2 |
| 20 |
9371508 | Selection for G156A O6-methylguanine DNA methyltransferase gene-transduced hematopoietic progenitors and protection from lethality in mice treated with O6-benzylguanine and 1,3-bis(2-chloroethyl)-1-nitrosourea. | 1997 Nov 15 |
1 |
| 21 |
8552605 | Increasing DNA repair methyltransferase levels via bone marrow stem cell transduction rescues mice from the toxic effects of 1,3-bis(2-chloroethyl)-1-nitrosourea, a chemotherapeutic alkylating agent. | 1996 Jan 9 |
4 |
| 22 |
9816307 | Retroviral-mediated gene transduction of human alkyltransferase complementary DNA confers nitrosourea resistance to human hematopoietic progenitors. | 1996 Aug |
2 |
| 23 |
7780976 | Retrovirus-mediated expression of a DNA repair protein in bone marrow protects hematopoietic cells from nitrosourea-induced toxicity in vitro and in vivo. | 1995 Jun 15 |
4 |
| 24 |
7923129 | Metabolism of O6-benzylguanine, an inactivator of O6-alkylguanine-DNA alkyltransferase. | 1994 Oct 1 |
1 |
| 25 |
1537073 | O6-methylguanine-DNA methyltransferase activity and induction of novel immunogenicity in murine tumor cells treated with methylating agents. | 1992 |
1 |