| 1 |
33884520 | Pyrrolizidine alkaloids cause cell cycle and DNA damage repair defects as analyzed by transcriptomics in cytochrome P450 3A4-overexpressing HepG2 clone 9 cells. | 2022 Apr |
2 |
| 2 |
33685126 | Prenatal Exposure to Retrorsine Induces Developmental Toxicity and Hepatotoxicity of Fetal Rats in a Sex-Dependent Manner: The Role of Pregnane X Receptor Activation. | 2021 Mar 17 |
1 |
| 3 |
34638760 | Metabolic Toxification of 1,2-Unsaturated Pyrrolizidine Alkaloids Causes Human Hepatic Sinusoidal Obstruction Syndrome: The Update. | 2021 Sep 27 |
1 |
| 4 |
32469285 | Establishment of a novel CYP3A4-transduced human hepatic sinusoidal endothelial cell model and its application in screening hepatotoxicity of pyrrolizidine alkaloids. | 2020 |
7 |
| 5 |
32682830 | Female-specific activation of pregnane X receptor mediates sex difference in fetal hepatotoxicity by prenatal monocrotaline exposure. | 2020 Nov 1 |
1 |
| 6 |
32798647 | Evaluation of pyrrolizidine alkaloid-induced genotoxicity using metabolically competent TK6 cell lines. | 2020 Nov |
2 |
| 7 |
32910235 | Structure-dependent genotoxic potencies of selected pyrrolizidine alkaloids in metabolically competent HepG2 cells. | 2020 Dec |
1 |
| 8 |
31103741 | Human CYP3A4-mediated toxification of the pyrrolizidine alkaloid lasiocarpine. | 2019 Aug |
1 |
| 9 |
29665350 | PXR: Structure-specific activation by hepatotoxic pyrrolizidine alkaloids. | 2018 May 25 |
2 |
| 10 |
25651456 | In silico prediction of the site of oxidation by cytochrome P450 3A4 that leads to the formation of the toxic metabolites of pyrrolizidine alkaloids. | 2015 Apr 20 |
3 |
| 11 |
24836403 | Metabolic activation of pyrrolizidine alkaloids: insights into the structural and enzymatic basis. | 2014 Jun 16 |
2 |