Nelfinavir

cytochrome P450 family 3 subfamily A member 4 ; Homo sapiens







21 Article(s)
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1 33483427 Nelfinavir and Its Active Metabolite M8 Are Partial Agonists and Competitive Antagonists of the Human Pregnane X Receptor. 2021 Mar 1
2 25571293 Pharmacokinetic modeling of simvastatin, nelfinavir and their interaction in humans. 2014 1
3 21682753 Differential effects of ethanol on spectral binding and inhibition of cytochrome P450 3A4 with eight protease inhibitors antiretroviral drugs. 2011 Dec 2
4 19931478 Analysis of CYP3A4-HIV-1 protease drugs interactions by computational methods for Highly Active Antiretroviral Therapy in HIV/AIDS. 2010 Jan 1
5 20861742 Nuclear receptor-mediated induction of CYP450 by antiretrovirals: functional consequences of NR1I2 (PXR) polymorphisms and differential prevalence in whites and sub-Saharan Africans. 2010 Dec 15 1
6 20937259 Effect of ethanol on spectral binding, inhibition, and activity of CYP3A4 with an antiretroviral drug nelfinavir. 2010 Nov 5 2
7 19478134 Pregnancy does not increase CYP3A or P-glycoprotein activity in the non-human primate, Macaca nemestrina. 2009 Aug 1
8 19500085 The in vivo response of novel buprenorphine metabolites, M1 and M3, to antiretroviral inducers and inhibitors of buprenorphine metabolism. 2009 Sep 1
9 17922881 Effect of CYP2C19 polymorphism on nelfinavir to M8 biotransformation in HIV patients. 2008 Apr 1
10 18576910 Possible antiretroviral therapy-warfarin drug interaction. 2008 Jul 1
11 17639026 Cytochrome P450 enzymes and transporters induced by anti-human immunodeficiency virus protease inhibitors in human hepatocytes: implications for predicting clinical drug interactions. 2007 Oct 1
12 15657782 Variations of CYP3A activity induced by antiretroviral treatment in HIV-1 infected patients. 2005 Feb 3
13 16267764 Pharmacogenetics of long-term responses to antiretroviral regimens containing Efavirenz and/or Nelfinavir: an Adult Aids Clinical Trials Group Study. 2005 Dec 1 1
14 15060514 Nelfinavir and felodipine: a cytochrome P450 3A4-mediated drug interaction. 2004 Apr 1
15 12949438 Inhibition of cytochrome P450 3A: relevant drug interactions in gastroenterology. 2003 1
16 12189360 Effect of coadministration of nelfinavir, indinavir, and saquinavir on the pharmacokinetics of amprenavir. 2002 Aug 1
17 11302944 Induction of P-glycoprotein and cytochrome P450 3A by HIV protease inhibitors. 2001 May 1
18 10926350 Drug interactions with cisapride: clinical implications. 2000 Jul 1
19 10939550 Variability in activity of hepatic CYP3A4 in patients infected with HIV. 2000 Aug 1
20 9649346 Metabolism of amprenavir in liver microsomes: role of CYP3A4 inhibition for drug interactions. 1998 Jul 1
21 9660842 Characterization of the selectivity and mechanism of human cytochrome P450 inhibition by the human immunodeficiency virus-protease inhibitor nelfinavir mesylate. 1998 Jul 7